Detection, characterization and biological activities of [bisphospho-thr3,9]ODN, an endogenous molecular form of ODN released by astrocytes.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Neuroscience

• Publication date

  2015-04-02

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.neuroscience.2015.01.045PMID 25639232
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Electrochemical methods for detection of post-translational modifications of proteins.

  2014cited by this paper
• The dual face of connexin-based astroglial Ca(2+) communication: a key player in brain physiology and a prime target in pathology.

  2014cited by this paper
• Endogenous positive allosteric modulation of GABA(A) receptors by diazepam binding inhibitor.

  2013cited by this paper
• Gliotransmission and Brain Glucose Sensing

  2013cited by this paper
• Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

  2012cited by this paper
• Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling.

  2012influential reference
• Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist.

  2012cited by this paper
• The Octadecaneuropeptide ODN Protects Astrocytes against Hydrogen Peroxide-Induced Apoptosis via a PKA/MAPK-Dependent Mechanism

  2012cited by this paper
• Protective effect of the octadecaneuropeptide on hydrogen peroxide‐induced oxidative stress and cell death in cultured rat astrocytes

  2011cited by this paper
• A closer look at the high affinity benzodiazepine binding site on GABAA receptors.

  2011cited by this paper
• Neuroanatomical characterization of two independent kisspeptin systems derived from evolutionary-ancient kiss genes in the brain of zebrafish

  2011cited by this paper
• Organization of two independent kisspeptin systems derived from evolutionary-ancient kiss genes in the brain of zebrafish.

  2011cited by this paper
• The complexity of the GABAA receptor shapes unique pharmacological profiles.

  2009cited by this paper
• Temperature and nitric oxide control spontaneous calcium transients in astrocytes.

  2008cited by this paper
• Acyl coenzyme A‐binding protein (ACBP) is phosphorylated and secreted by retinal Müller astrocytes following protein kinase C activation

  2008influential reference
• Pharmacological Characterization of the Receptor Mediating the Anorexigenic Action of the Octadecaneuropeptide: Evidence for an Endozepinergic Tone Regulating Food Intake

  2007cited by this paper
• Cell stem cell.

  2007cited by this paper
• Impact of subunit positioning on GABAA receptor function.

  2006cited by this paper
• In vivo action of a new octadecaneuropeptide antagonist on neuropeptide Y and corticotropin-releasing hormone mRNA levels in rat.

  2005cited by this paper
• Somatostatin down‐regulates the expression and release of endozepines from cultured rat astrocytes via distinct receptor subtypes

  2005cited by this paper
• Activity-Dependent Expression of Acyl-Coenzyme A-Binding Protein in Retinal Muller Glial Cells Evoked by Optokinetic Stimulation

  2004cited by this paper
• In vivo action of a new octadecaneuropeptide (ODN) antagonist on gonadotropin-releasing hormone gene expression in the male rat brain.

  2004cited by this paper
• The role of Ca2+ in the generation of spontaneous astrocytic Ca2+ oscillations.

  2003cited by this paper
• Effect of Intracerebroventricular Administration of the Octadecaneuropeptide on the Expression of Pro‐Opiomelanocortin, Neuropeptide Y and Corticotropin‐Releasing Hormone mRNAs in Rat Hypothalamus

  2003cited by this paper
• Subunit composition, distribution and function of GABA(A) receptor subtypes.

  2002cited by this paper
• Cellular localization of the diazepam binding inhibitor in glial cells with special reference to its coexistence with brain-type fatty acid binding protein.

  2002cited by this paper
• Effect of diazepam binding inhibitor (DBI) on the fluid intake, preference and the taste reactivity in mice.

  2001cited by this paper
• The octadecaneuropeptide [diazepam-binding inhibitor (33-50)] exerts potent anorexigenic effects in rodents.

  2001cited by this paper
• Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN. Design of a potent endozepine antagonist.

  2001cited by this paper
• The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central‐type benzodiazepine receptors

  2001cited by this paper
• Involvement of diazepam binding inhibitor and its fragment octadecaneuropeptide in social isolation stress-induced decrease in pentobarbital sleep in mice.

  1999cited by this paper
• Sequencing of peptides phosphorylated on serines and threonines by post-source decay in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  1999cited by this paper
• Protein phosphorylation and signal transduction.

  1999cited by this paper
• The endozepine ODN stimulates [3H]thymidine incorporation in cultured rat astrocytes.

  1999cited by this paper
• Reduction of pentylenetetrazol-induced convulsions by the octadecaneuropeptide ODN.

  1999cited by this paper
• The octadecaneuropeptide ODN induces anxiety in rodents: possible involvement of a shorter biologically active fragment.

  1998cited by this paper
• Structure-activity relationships of a series of analogues of the octadecaneuropeptide ODN on calcium mobilization in rat astrocytes.

  1998cited by this paper
• The stimulatory effect of the octadecaneuropeptide (ODN) on cytosolic Ca2+ in rat astrocytes is not mediated through classical benzodiazepine receptors.

  1997cited by this paper
• Signaling through scaffold, anchoring, and adaptor proteins.

  1997cited by this paper
• The endogenous benzodiazepine receptor ligand ODN increases cytosolic calcium in cultured rat astrocytes.

  1996cited by this paper
• The endozepine ODN stimulates polyphosphoinositide metabolism in rat astrocytes

  1995cited by this paper
• Diazepam binding inhibitor fragment 33–50 (octadecaneuropeptide) immunoreactivity in the cerebellar cortex is restricted to glial cells

  1994cited by this paper
• Extreme stability of Tyr-MIF-1 in CSF.

  1994cited by this paper
• Allosteric Modulation of the GABA‐Induced Chloride Current in Frog Melanotrophs a

  1993cited by this paper
• On target with a new mechanism for the regulation of protein phosphorylation.

  1993cited by this paper
• Ontogeny of diazepam-binding inhibitor-related peptides (endozepines) in the rat brain.

  1993cited by this paper
• Electrophysiological characterization of diazepam binding inhibitor (DBI) on GABAA receptors

  1991cited by this paper
• Structure of the macroglia of the retina: Sharing and division of labour between astrocytes and Müller cells

  1991cited by this paper
• Immunocytochemical localization of the endogenous benzodiazepine ligand octadecaneuropeptide (ODN) in the rat brain.

  1990cited by this paper
• Isolation and Characterization of a Rat Brain Triakontatetraneuropeptide, a Posttranslational Product of Diazepam Binding Inhibitor: Specific Action at the Ro 5‐4864 Recognition Site

  1989cited by this paper
• Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain.

  1986cited by this paper
• An octadecaneuropeptide (ODN) derived from diazepam binding inhibitor increases aggressive interactions in mice.

  1986cited by this paper
• A brain octadecaneuropeptide generated by tryptic digestion of DBI (diazepam binding inhibitor) functions as a proconflict ligand of benzodiazepine recognition sites.

  1984cited by this paper
• Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.

  1983cited by this paper
• Biological and radioimmunological evidence for melanocyte stimulating hormones (MSH) of extrapituitary origin in the rat brain.

  1978cited by this paper
• Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse.

  1957influential reference

• Octadecaneuropeptide promotes the migration of astrocyte via ODN metabotropic receptor and calcium signaling pathway.

  2025cites this paper
• Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis.

  2025cites this paper
• Dose-Dependent Dual Effect of the Endozepine ODN on Neuronal Spiking Activity

  2025cites this paper
• Benzodiazepines compromise the outcome of cancer immunotherapy

  2024cites this paper
• Peripheral gating of mechanosensation by glial diazepam binding inhibitor

  2024cites this paper
• Lactobacillus salivarius and Lactobacillus gasseri supplementation reduces stress-induced sugar craving in mice.

  2023cites this paper
• Peripheral gating of pain by glial endozepine

  2023cites this paper
• Concentration dependent dual effect of the endozepine ODN on neuronal spiking activity

  2022cites this paper
• Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

  2020cites this paper
• Endozepines and their receptors: Structure, functions and pathophysiological significance.

  2020cites this paper
• The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABAA Receptors, Boosts Functional Recovery after Stroke

  2020cites this paper
• Pharmacological characterisation of GABA receptors in potential spinal cord neural stem cells

  2019cites this paper
• Harmony and Distress: Humor, Culture, and Psychological Well-Being in South Korean Organizations

  2019cites this paper
• Endogenous Expression of ODN-Related Peptides in Astrocytes Contributes to Cell Protection Against Oxidative Stress: Astrocyte-Neuron Crosstalk Relevance for Neuronal Survival

  2018cites this paper
• “Probe, Sample, and Instrument (PSI)”: The Hat-Trick for Fluorescence Live Cell Imaging

  2018cites this paper
• Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson’s disease

  2018cites this paper
• Etude des mécanismes cellulaires et moléculaires impliqués dans les effets neuroprotecteurs du gliopeptide OctaDecaNeuropeptide (ODN) dans un model murin de la Maladie de Parkinson

  2017cites this paper