Ether lipid 1-O-octadecyl-2-O-methyl-3-glycero-phosphocholine inhibits cell-cell adhesion through translocation and clustering of E-cadherin and episialin in membrane microdomains.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Oncology Report

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.3892/OR.19.1.123PMID 18097585
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clustering of monosialyl-Gb5 initiates downstream signalling events leading to invasion of MCF-7 breast cancer cells.

  2007cited by this paper
• Clustering of monosialyl-Gb 5 initiates downstream signalling events leading to invasion of MCF-7 breast cancer cells

  2007cited by this paper
• Rafts defined: a report on the Keystone symposium on lipid rafts and cell function Published, JLR Papers in Press, April 27, 2006.

  2006cited by this paper
• ET-18-OCH3 inhibits the phosphorylation and activation of p70 S6 kinase in MCF-7 cells.

  2005cited by this paper
• N-cadherin association with lipid rafts regulates its dynamic assembly at cell-cell junctions in C2C12 myoblasts.

  2005cited by this paper
• Role of early plasma membrane events in chemotherapy-induced cell death.

  2005cited by this paper
• ET‐18‐O‐CH3‐induced apoptosis is causally linked to COX‐2 upregulation in H‐ras transformed human breast epithelial cells

  2005cited by this paper
• ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor.

  2004cited by this paper
• Monosialyl‐Gb5 organized with cSrc and FAK in GEM of human breast carcinoma MCF‐7 cells defines their invasive properties

  2002cited by this paper
• The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells.

  2001cited by this paper
• A guide to monoclonal antibodies directed to glycotopes.

  2001influential reference
• Alkyl‐lysophospholipid 1‐O‐octadecyl‐2‐O‐methyl‐ glycerophosphocholine induces invasion through episialin‐mediated neutralization of E‐cadherin in human mammary MCF‐7 cells in vitro

  2001cited by this paper
• Lipid rafts and signal transduction

  2000cited by this paper
• The Role of E-Cadherin-Catenin Complex: More Than an Intercellular Glue?

  2000cited by this paper
• Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts*

  2000cited by this paper
• New insights in glycosphingolipid function: "glycosignaling domain," a cell surface assembly of glycosphingolipids with signal transducer molecules,involved in cell adhesion coupled with signaling.

  1998cited by this paper
• GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells*

  1998cited by this paper
• Expression of Globo‐series Gangliosides in Human Renal Cell Carcinoma

  1997cited by this paper
• A close association of GM3 with c-Src and Rho in GM3-enriched microdomains at the B16 melanoma cell surface membrane: a preliminary note.

  1997cited by this paper
• Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism.

  1996cited by this paper
• Revisiting the fluid mosaic model of membranes.

  1995cited by this paper
• Common tetrasaccharide epitope NeuAc alpha 2-->3Gal beta 1-->3(Neu-Ac alpha 2-->6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities.

  1994cited by this paper
• Changes in glycolipids in human renal‐cell carcinoma and their clinical significance

  1991cited by this paper
• Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro.

  1991influential reference
• Application of the MTT assay to human prostate cancer cell lines in vitro: Establishment of test conditions and assessment of hormone‐stimulated growth and drug‐induced cytostatic and cytotoxic effects

  1988cited by this paper

• 1-O-octadecyl-2-O-methylglycero-3-phosphocholine (Edelfosine) and cancer cell invasion: a short review.

  2014cites this paper
• Lipid rafts enriched in monosialylGb5Cer carrying the stage-specific embryonic antigen-4 epitope are involved in development of mouse preimplantation embryos at cleavage stage

  2011cites this paper
• Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane

  2010cites this paper