Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells

Thushara P. Abeyweera,Ernesto Merino,M. Huse

Published 2011 in Journal of Cell Biology

ABSTRACT

Signaling from immunotyrosine-based inhibitory motifs (ITIMs) neutralizes activating signals by inducing a retraction of NK cells from the surface of stimulatory cells.

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