Riluzole enhances the anti-seizure action of conventional antiepileptic drugs against pentetrazole-induced convulsions in mice.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Polish Journal of Pharmacology

• Publication date

  2004-03-01

• Fields of study

  Medicine

• Identifiers
  PMID 15156069
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Potential in Amyotrophic Lateral Sclerosis

  2012cited by this paper
• Influence of SIB 1893, a selective mGluR5 receptor antagonist, on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy.

  2003cited by this paper
• Sib 1893 possesses pro- and anticonvulsant activity in the electroshock seizure threshold test in mice.

  2002cited by this paper
• Effect of riluzole on the acquisition and expression of amygdala kindling.

  2001cited by this paper
• The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK.

  2000cited by this paper
• NMDA and AMPA/kainate receptors are involved in the anticonvulsant activity of riluzole in DBA/2 mice.

  2000cited by this paper
• The Neuroprotective Agent Riluzole Activates the Two P Domain K+ Channels TREK-1 and TRAAK

  2000cited by this paper
• Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex.

  2000cited by this paper
• Effect of riluzole on the neurological and neuropathological changes in an animal model of cardiac arrest-induced movement disorder.

  1999cited by this paper
• Electrophysiology of the neuroprotective agent riluzole on striatal spiny neurons.

  1998cited by this paper
• LY 300164, a novel antagonist of AMPA/kainate receptors, potentiates the anticonvulsive activity of antiepileptic drugs.

  1998cited by this paper
• Riluzole, a glutamate release inhibitor, and motor behavior

  1998influential reference
• Riluzole Does Not Attenuate Increases in Hippocampal Glutamate Concentrations in a Rabbit Model of Repeated Transient Global Cerebral Ischemia

  1998cited by this paper
• Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons.

  1998cited by this paper
• Glutamate in CNS disorders as a target for drug development: an update.

  1998cited by this paper
• Riluzole. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis.

  1996cited by this paper
• Interaction of Calcium Channel Blockers and Excitatory Amino Acid Antagonists with Conventional Antiepileptic Drugs

  1996cited by this paper
• A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Potential in Amyotrophic Lateral Sclerosis

  1996cited by this paper
• Inhibition by riluzole of glycinergic postsynaptic currents in rat hypoglossal motoneurones

  1995cited by this paper
• The non-competitive AMPA/kainate receptor antagonist, GYKI 52466, potentiates the anticonvulsant activity of conventional antiepileptics.

  1995cited by this paper
• Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission.

  1995cited by this paper
• Prevention of HIV coat protein (gp120) toxicity in cortical cell cultures by riluzole.

  1994cited by this paper
• Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole.

  1994cited by this paper
• Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices.

  1994cited by this paper
• The competitive NMDA antagonist, D-CPP-ene, potentiates the anticonvulsant activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.

  1994cited by this paper
• Riluzole, a novel antiglutamate, blocks GABA uptake by striatal synaptosomes.

  1994influential reference
• Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics.

  1993cited by this paper
• Modulation of the seizure threshold for excitatory amino acids in mice by antiepileptic drugs and chemoconvulsants.

  1993cited by this paper
• Competitive antagonists of NMDA receptors, CGP 37849 and CGP 39551, enhance the anticonvulsant activity of valproate against electroconvulsions in mice.

  1993cited by this paper
• 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline enhances the protective activity of common antiepileptic drugs against maximal electroshock-induced seizures in mice.

  1993cited by this paper
• Effects of riluzole (2‐amino‐6‐trifluoromethoxy benzothiazole) on striatal neurochemical markers in the rat, with special reference to the dopamine, choline, GABA and glutamate synaptosomal high affinity uptake systems

  1992cited by this paper
• Influence of MK-801 on the anticonvulsant activity of antiepileptics.

  1991cited by this paper
• Riluzole prevents hyperexcitability produced by the mast cell degranulating peptide and dendrotoxin I in the rat.

  1991cited by this paper
• The competitive NMDA receptor antagonists CGP 37849 and CGP 39551 are potent, orally-active anticonvulsants in rodents

  1990cited by this paper
• Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations.

  1988cited by this paper
• Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks

  1986cited by this paper
• 2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--I. Anticonvulsant properties.

  1985cited by this paper
• Une nouvelle méthode simple pour explorer l’action «tranquillisante»: le test de la cheminée

  1960cited by this paper
• A simplified method of evaluating dose-effect experiments.

  1948cited by this paper

• Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation

  2024cites this paper
• Riluzole attenuates acute neural injury and reactive gliosis, hippocampal-dependent cognitive impairments and spontaneous recurrent generalized seizures in a rat model of temporal lobe epilepsy

  2024cites this paper
• Neuroprotective effects of riluzole in Alzheimer's disease: A comprehensive review

  2023cites this paper
• An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists

  2023cites this paper
• The Role of Glutamate Receptors in Epilepsy

  2023cites this paper
• Riluzole and novel naphthalenyl substituted aminothiazole derivatives prevent acute neural excitotoxic injury in a rat model of temporal lobe epilepsy

  2022cites this paper
• Role of glutamate excitotoxicity and glutamate transporter EAAT2 in epilepsy: opportunities for novel therapeutics development.

  2021cites this paper
• Riluzole attenuates the efficacy of glutamatergic transmission by interfering with the size of the readily releasable neurotransmitter pool

  2018cites this paper
• The effect of riluzole alone and in combination with sodium valproate on pentylenetetrazole induced seizures in swiss-albino rats

  2016cites this paper
• Are big potassium-type Ca2+-activated potassium channels a viable target for the treatment of epilepsy?

  2015cites this paper
• A Synopsis of Nano-Technological Approaches Toward Anti-Epilepsy Therapy: Present and Future Research Implications.

  2015cites this paper
• Riluzole prevents soluble Aβ1–42 oligomers-induced perturbation of spontaneous discharge in the hippocampal CA1 region of rats

  2015cites this paper
• Riluzole: validation of stability-indicating HPLC, D1 and DD1 spectrophotometric assays.

  2014cites this paper
• Riluzole attenuates the effects of chemoconvulsants acting on glutamatergic and GABAergic neurotransmission in the planarian Dugesia tigrina.

  2013cites this paper
• The NMDA receptor complex as a therapeutic target in epilepsy: a review.

  2011cites this paper
• Riluzole in the Treatment of Mood and Anxiety Disorders

  2008cites this paper
• In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates

  2005cites this paper
• Valproic acid alters chromatin structure by regulation of chromatin modulation proteins.

  2005cites this paper