Clustered DNA damage induced by heavy ion particles.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Uchū Seibutsu Kagaku

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.2187/BSS.18.206PMID 15858387
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks.

  2004cited by this paper
• Detection of endonuclease III- and 8-oxoguanine glycosylase-sensitive base modifications in gamma-irradiated DNA and cells by the aldehyde reactive probe (ARP) assay.

  2004cited by this paper
• Quantifying double-strand breaks and clustered damages in DNA by single-molecule laser fluorescence sizing.

  2003cited by this paper
• Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis.

  2003cited by this paper
• High efficiency detection of bi-stranded abasic clusters in -irradiated DNA by putrescine

  2002cited by this paper
• High efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescine.

  2002cited by this paper
• Clustered DNA damages induced in human hematopoietic cells by low doses of ionizing radiation.

  2002cited by this paper
• Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease.

  2002cited by this paper
• Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites.

  2002cited by this paper
• Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli

  2001cited by this paper
• Genome maintenance mechanisms for preventing cancer

  2001cited by this paper
• Human DNA Repair Genes

  2001cited by this paper
• Base excision repair processing of radiation-induced clustered DNA lesions.

  2001cited by this paper
• Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation.

  2000cited by this paper
• Clustered DNA Damage, Influence on Damage Excision by XRS5 Nuclear Extracts and Escherichia coli Nth and Fpg Proteins*

  2000cited by this paper
• DNA strand-break yields after post-irradiation incubation with base excision repair endonucleases implicate hydroxyl radical pairs in double-strand break formation.

  2000cited by this paper
• DNA damage and repair in individual cells: applications of the comet assay in radiobiology.

  1999influential reference
• Influence of radiation quality on the yield of DNA strand breaks in SV40 DNA irradiated in solution.

  1999cited by this paper
• In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites.

  1999cited by this paper
• A study of endonuclease III-sensitive sites in irradiated DNA: detection of alpha-particle-induced oxidative damage.

  1999cited by this paper
• Track structure in radiation biology: theory and applications.

  1998cited by this paper
• Multiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIII.

  1998cited by this paper
• Enzymatic processing of radiation-induced free radical damage in DNA.

  1998cited by this paper
• Image analysis of comet assay measurements.

  1997cited by this paper
• DNA double-strand break distributions in X-ray and alpha-particle irradiated V79 cells: evidence for non-random breakage.

  1997cited by this paper
• Dose-rate effect on radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line.

  1996cited by this paper
• Oxidative DNA damage through long-range electron transfer

  1996cited by this paper
• The difference that linear energy transfer makes to precursors of DNA strand breaks.

  1996cited by this paper
• Double strand breaks induced by low doses of gamma rays or heavy ions: quantitation in nonradioactive human DNA.

  1996cited by this paper
• Clusters of DNA damage induced by ionizing radiation: formation of short DNA fragments. II. Experimental detection.

  1996cited by this paper
• Detection of purine lesions in cellular DNA using single cell gel electrophoresis with Fpg protein.

  1995cited by this paper
• The action of Escherichia coli endonuclease III on multiply damaged sites in DNA.

  1995cited by this paper
• Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

  1994cited by this paper
• The complexity of DNA damage: relevance to biological consequences.

  1994cited by this paper
• Yield of strand breaks as a function of scavenger concentration and LET for SV40 irradiated with 4He ions.

  1993cited by this paper
• Detection of DNA double-strand breaks through the cell cycle after exposure to X-rays, bleomycin, etoposide and 125IdUrd.

  1993cited by this paper
• Single-cell gel technique supports hit probability calculations.

  1993cited by this paper
• Lethality of heavy ion-induced DNA double-strand breaks in mammalian cells.

  1993cited by this paper
• Application of pulsed field gel electrophoresis to determine gamma-ray-induced double-strand breaks in yeast chromosomal molecules.

  1993cited by this paper
• Model of DNA damage induced by radiations of various qualities.

  1992cited by this paper
• Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis.

  1991cited by this paper
• The formation of strand breaks in DNA after high-LET irradiation: a comparison of data from in vitro and cellular systems.

  1990cited by this paper
• In CHEF electrophoresis a linear induction of dsb corresponds to a nonlinear fraction of extracted DNA with dose.

  1990cited by this paper
• DNA double-strand break analysis by CHEF (clamped homogeneous electrical field) electrophoresis.

  1990cited by this paper
• DNA Double-strand Break Analysis by CHEF Electrophoresis

  1990cited by this paper
• Radiation biology in space: a critical review.

  1989cited by this paper
• DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability.

  1988cited by this paper
• High-resolution separation and accurate size determination in pulsed-field gel electrophoresis of DNA. 3. Effect of electrical field shape.

  1988cited by this paper
• The Chemical Basis of Radiation Biology

  1987cited by this paper
• Quantitation of radiation-, chemical-, or enzyme-induced single strand breaks in nonradioactive DNA by alkaline gel electrophoresis: application to pyrimidine dimers.

  1986cited by this paper
• Radiation-induced strand breaks in phi X174 replicative form DNA: an improved experimental and theoretical approach.

  1985cited by this paper
• Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis.

  1984cited by this paper
• Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells.

  1984cited by this paper
• Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis.

  1984cited by this paper
• Elemental and Isotopic Composition of the Galactic Cosmic Rays

  1983cited by this paper
• Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals.

  1981cited by this paper
• Quantitation of the repair of gamma-radiation-induced double-strand DNA breaks in human fibroblasts.

  1981cited by this paper
• Measurement of the kinetics of DNA double strand break repair in Ehrlich ascites tumour cells using the unwinding method.

  1980cited by this paper
• X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution.

  1979cited by this paper
• Fractionation of DNA from mammalian cells by alkaline elution.

  1976cited by this paper
• Estimation of life times and diffusion distances of radicals involved in x-ray-induced DNA strand breaks of killing of mammalian cells.

  1975influential reference
• The rate of strand separation in alkali of DNA of irradiated mammalian cells.

  1975cited by this paper
• Radiation induced strand breakage in DNA from mammalian cells. Strand separation in alkaline solution.

  1973cited by this paper
• Heavy-ion-induced single- and double-strand breaks in phiX-174 replicative form DNA.

  1972cited by this paper
• Linear energy transfer

  1970cited by this paper
• Tables for estimating sedimentation through linear concentration gradients of sucrose solution.

  1967cited by this paper
• Theory of RBE for heavy ion bombardment of dry enzymes and viruses.

  1967cited by this paper

• Comparison of mutation spectra induced by gamma-rays and carbon ion beams

  2024influential citation
• Deciphering repair pathways of clustered DNA damage in human TK6 cells: insights from atomic force microscopy direct visualization

  2024cites this paper
• Short Double-Stranded DNA (≤40-bp) Affects Repair Pathway Choice

  2023cites this paper
• Role of DNA repair pathways in the recovery of a dried, radioresistant cyanobacterium exposed to high-LET radiation: implications for the habitability of Mars

  2022cites this paper
• Formation of clustered DNA damage in vivo upon irradiation with ionizing radiation: Visualization and analysis with atomic force microscopy

  2022cites this paper
• Heavy-ion beam-induced reactive oxygen species and redox reactions

  2021cites this paper
• Insights into the Survival Capabilities of Cryomyces antarcticus Hydrated Colonies after Exposure to Fe Particle Radiation

  2021cites this paper
• High-Dose Irradiation Inhibits Motility and Induces Autophagy in Caenorhabditis elegans

  2021cites this paper
• Clustered DNA Damage: Electronic Properties and Their Influence on Charge Transfer. 7,8-Dihydro-8-Oxo-2′-Deoxyguaosine Versus 5′,8-Cyclo-2′-Deoxyadenosines: A Theoretical Approach

  2020cites this paper
• Neutron detection techniques from μeV to GeV

  2020cites this paper
• The Influence of Single, Tandem, and Clustered DNA Damage on the Electronic Properties of the Double Helix: A Theoretical Study

  2020cites this paper
• A novel Tissue Equivalent Proportional Counter for microdosimetry at nanometer scale

  2018cites this paper
• Comparison of human lung cancer cell radiosensitivity after irradiations with therapeutic protons and carbon ions

  2017cites this paper
• Title Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p 53-Null Cancer Cellsby Inducing Mitotic Catastrophe

  2017cites this paper
• Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin

  2017cites this paper
• The Effects of HZE Particles, γ and X-ray Radiation on the Survival and Genetic Integrity of Halobacterium salinarum NRC-1, Halococcus hamelinensis, and Halococcus morrhuae

  2017cites this paper
• G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.

  2016cites this paper
• Flavonoids of Rosa roxburghii Tratt exhibit radioprotection and anti-apoptosis properties via the Bcl-2(Ca2+)/Caspase-3/PARP-1 pathway

  2016cites this paper
• Carbon ion beam triggers both caspase-dependent and caspase-independent pathway of apoptosis in HeLa and status of PARP-1 controls intensity of apoptosis

  2015cites this paper
• The EGFR mutation status affects the relative biological effectiveness of carbon-ion beams in non-small cell lung carcinoma cells

  2015cites this paper
• Proton-induced direct and indirect damage of plasmid DNA

  2015cites this paper
• Effects of X-ray and carbon ion beam irradiation on membrane permeability and integrity in Saccharomyces cerevisiae cells

  2015cites this paper
• Radiosensitizing effect of carboplatin and paclitaxel to carbon-ion beam irradiation in the non-small-cell lung cancer cell line H460

  2015cites this paper
• Investigation of X-ray permeability of surgical gloves coated with different contrast agents

  2015cites this paper
• Contribution of indirect effects to clustered damage in DNA irradiated with protons.

  2015cites this paper
• Role of isolated and clustered DNA damage and the post-irradiating repair process in the effects of heavy ion beam irradiation

  2015cites this paper
• Impacts of X-ray irradiation on Saccharomyces cerevisiae cells growth and physiological-biochemical characteristic

  2015cites this paper
• Quantitative characteristics of clustered DNA damage in irradiated cells by heavy ion beams

  2014cites this paper
• Clustered DNA damage on subcellular level: effect of scavengers

  2014cites this paper
• Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p53-Null Cancer Cells by Inducing Mitotic Catastrophe

  2014cites this paper
• Clustered DNA damage induced by protons radiation in plasmid DNA

  2013cites this paper
• Characteristics of Myeloid Differentiation and Maturation Pathway Derived from Human Hematopoietic Stem Cells Exposed to Different Linear Energy Transfer Radiation Types

  2013cites this paper
• The AMERE project: Enabling real-time detection of radiation effects in individual cells in deep space

  2012cites this paper
• Limited Repair of Critical DNA Damage in Cells Exposed to Low Dose Radiation

  2012influential citation
• Functions of the MRE11-RAD50-NBS1 complex in DNA double strand break repair

  2012cites this paper
• Absolute measurements of radiation damage in nanometer-thick films.

  2012cites this paper
• Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.

  2012cites this paper
• The First Life Science Experiments in ISS: Reports of "Rad Gene"-Space Radiation Effects on Human Cultured Cells-

  2010cites this paper
• Study on DNA Damage Induced by Neon Beam Irradiation in Saccharomyces Cerevisiae

  2010cites this paper
• The influence of reduced glutathione on chromosome damage induced by X-rays or heavy ion beams of different LETs and on the interaction of DNA lesions induced by radiations and bleomycin.

  2010cites this paper
• A nanodosimetric model of radiation-induced clustered DNA damage yields

  2010cites this paper
• Assessment of γH2AX nuclear foci number and size in normal and repair-deficient cells irradiated with low and high linear energy transfer radiation

  2010cites this paper
• Ceramide induces myogenic differentiation and apoptosis in Drosophila Schneider cells.

  2009cites this paper
• Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

  2009cites this paper
• Scanning force microscopy studies of X-ray-induced double-strand breaks in plasmid DNA

  2009cites this paper
• Detection of space radiation-induced double strand breaks as a track in cell nucleus.

  2009cites this paper
• DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus.

  2008cites this paper
• High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase‐9 activation

  2008cites this paper
• High LET heavy ion radiation induces lower numbers of initial chromosome breaks with minimal repair than low LET radiation in normal human cells.

  2008cites this paper
• Quantitative analysis of isolated and clustered DNA damage induced by gamma-rays, carbon ion beams, and iron ion beams.

  2008cites this paper
• Formation of clustered DNA damage after high-LET irradiation: a review.

  2008cites this paper
• AFLP Analysis of Arabidopsis Thaliana Treated by Low-Energy Ion Beam

  2007cites this paper
• SFM studies of carbon ion induced damages in plasmid DNA

  2007cites this paper
• Radio-resistance induced by nitric oxide to heavy ion irradiation in A172 human glioma cells

  2007cites this paper
• High relative biologic effectiveness of carbon ion radiation on induction of rat mammary carcinoma and its lack of H-ras and Tp53 mutations.

  2007cites this paper
• The Rough Guide to the Moon and Mars

  2007cites this paper
• Generierung und Prozessierung oxidativer DNA-Schäden

  2006cites this paper
• Specificity of mutations induced by carbon ions in budding yeast Saccharomyces cerevisiae.

  2006cites this paper