Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis.

B. Wajchenberg,M. Nery,M. Cunha,M. E. R. Silva

Published 2009 in Arquivos brasileiros de endocrinologia e metabologia

ABSTRACT

The authors analyze insulin resistance, the metabolic syndrome and endothelial dysfunction as consequence of a common antecedent, a low grade inflammation, indicating that in obesity there is a chronically activated inflammatory state of the adipose tissue. Furthermore, the inflammatory signaling is discussed according to the adipose tissue depot, visceral or subcutaneous.

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