Endothelial hyper‐permeability and cardiomyocyte dysfunction following Coronary Artery Bypass Grafting

M. Velten,G. Duerr,M. Hamiko,S. Frede,L. Rogers,G. Baumgarten,A. Hoeft,T. Hilbert

Published 2016 in The FASEB Journal

ABSTRACT

Ischemia Reperfusion Injury (IRI) is contributing to morbidity and mortality in various cardiac diseases including coronary artery bypass graft surgery (CABG). We hypothesized that CABG induced IRI is resulting in capillary leakage due to Angiopoietins (ANG) and cardiomyocytes dysfunction affecting perioperative morbidity after CABG.

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