H5N1 influenza viruses: Facts, not fear

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2012-01-25

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1073/pnas.1121297109PMID 22308474PMCID PMC3289294
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011cited by this paper
• Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus

  2010cited by this paper
• Seroprevalence of anti-H5 antibody in rural Cambodia, 2007.

  2010cited by this paper
• Kinetics of Neutralizing Antibodies in Patients Naturally Infected by H5N1 Virus

  2010cited by this paper
• Receptor Specificity and Transmission of H2N2 Subtype Viruses Isolated from the Pandemic of 1957

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• Influenza A (H5N1) Viruses from Pigs, Indonesia

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• Ferrets develop fatal influenza after inhaling small particle aerosols of highly pathogenic avian influenza virus A/Vietnam/1203/2004 (H5N1)

  2010cited by this paper
• The mouse model is suitable for the study of viral factors governing transmission and pathogenesis of highly pathogenic avian influenza (HPAI) viruses in mammals

  2010cited by this paper
• Animal models for the preclinical evaluation of candidate influenza vaccines

  2010cited by this paper
• Pathogenesis and Transmission of Triple-Reassortant Swine H1N1 Influenza Viruses Isolated before the 2009 H1N1 Pandemic

  2010cited by this paper
• In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

  2009cited by this paper
• Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air

  2009cited by this paper
• An early 'classical' swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice.

  2009cited by this paper
• Polymorphisms of methylenetetrahydrofolate reductase and methionine synthase genes and bladder cancer risk: a case–control study with meta-analysis

  2009cited by this paper
• Avian influenza A H5N1 infections in Bali province, Indonesia: a behavioral, virological and seroepidemiological study

  2009cited by this paper
• Aerosol transmission of influenza A virus: a review of new studies

  2009cited by this paper
• Use of animal models to understand the pandemic potential of highly pathogenic avian influenza viruses.

  2009cited by this paper
• Seroprevalence of Antibodies to Avian Influenza Virus A (H5N1) among Residents of Villages with Human Cases, Thailand, 2005

  2009cited by this paper
• Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice

  2009cited by this paper
• Prevalence of Antibodies against Avian Influenza A (H5N1) Virus among Cullers and Poultry Workers in Ho Chi Minh City, 2005

  2009cited by this paper
• Antibodies against H5 and H9 avian influenza among poultry workers in China.

  2009cited by this paper
• Risk factors associated with subclinical human infection with avian influenza A (H5N1) virus--Cambodia, 2006.

  2009cited by this paper
• Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

  2009cited by this paper
• Live attenuated vaccines for pandemic influenza.

  2009cited by this paper
• Potential infections of H5N1 and H9N2 avian influenza do exist in Guangdong populations of China.

  2008cited by this paper
• Pathogenesis of Avian Influenza (H7) Virus Infection in Mice and Ferrets: Enhanced Virulence of Eurasian H7N7 Viruses Isolated from Humans

  2007cited by this paper
• Reports of Avian Influenza H5N1 in Cats and Dogs

  2007cited by this paper
• Identification of H2N3 influenza A viruses from swine in the United States

  2007cited by this paper
• Scientific barriers to developing vaccines against avian influenza viruses

  2007cited by this paper
• Cases of swine influenza in humans: a review of the literature.

  2007cited by this paper
• Inefficient Transmission of H5N1 Influenza Viruses in a Ferret Contact Model

  2007cited by this paper
• Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

  2006cited by this paper
• The guinea pig as a transmission model for human influenza viruses.

  2006cited by this paper
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  2006cited by this paper
• Lack of transmission of H5N1 avian–human reassortant influenza viruses in a ferret model

  2006cited by this paper
• Characterization of the 1918 influenza virus polymerase genes

  2005influential reference
• Avian Influenza (H5N1) Viruses Isolated from Humans in Asia in 2004 Exhibit Increased Virulence in Mammals

  2005cited by this paper
• Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus

  2005influential reference
• Avian influenza A(H5N1)--situation (poultry) in Asia as at 2 March 2004: need for a long-term response, comparison with previous outbreaks.

  2004cited by this paper
• Avian H5N1 Influenza in Cats

  2004cited by this paper
• Pathogenesis of Avian Influenza A (H5N1) Viruses in Ferrets

  2002cited by this paper
• Risk of influenza A (H5N1) infection among poultry workers, Hong Kong, 1997-1998.

  2002cited by this paper
• Receptor specificity of influenza virus influences severity of illness in ferrets.

  1995cited by this paper
• Comparisons of virulence of influenza virus recombinants in ferrets in relation to their behaviour in man and their genetic constitution.

  1979cited by this paper

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• Agent-Based Models of Dual-Use Research Restrictions

  2020cites this paper
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  2020cites this paper
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  2019cites this paper
• Inferring determinants of viral transmission using short-read sequence data

  2019cites this paper
• Peculiarities of the influenza viruses circulation and their properties during 2018-2019 epidemic season in Russia and countries of the Northern Hemisphere

  2019cites this paper
• Особенности циркуляции и свойств вирусов гриппа в эпидемическом сезоне 2018-2019 гг. в России и странах Северного полушария

  2019cites this paper
• Why Do Exceptionally Dangerous Gain-of-Function Experiments in Influenza?

  2018cites this paper
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  2018cites this paper
• A novel framework for inferring parameters of transmission from viral sequence data

  2018cites this paper
• Identification of novel inhibitor against endonuclease subunit of Influenza pH1N1 polymerase: A combined molecular docking, molecular dynamics, MMPBSA, QMMM and ADME studies to combat influenza A viruses

  2018cites this paper
• A fragile assemblage: Mutant bird flu and the limits of risk assessment

  2017cites this paper
• Functional Proteomic Studies of Lycorine-treated MDCK Cells on Highly Pathogenic Avian Influenza H5N1 Virus Infection

  2017cites this paper
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  2017cites this paper
• Does influenza pandemic preparedness and mitigation require gain‐of‐function research?

  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
• Host-adaptive mechanism of H5N1 avian influenza virus hemagglutininn.

  2015cites this paper
• Studies on Influenza Virus Transmission between Ferrets: the Public Health Risks Revisited

  2015cites this paper
• Dual-use research and the H5N1 bird flu: Is restricting publication the solution to biosecurity issues?

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  2014cites this paper
• Ethical Alternatives to Experiments with Novel Potential Pandemic Pathogens

  2014cites this paper
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  2013cites this paper
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  2013cites this paper
• Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis

  2013cites this paper
• H5N1 vaccines in humans.

  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
• Emerging Antiviral Strategies to Interfere with Influenza Virus Entry

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  2013cites this paper
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• Avian influenza A H5N1 virus: a continuous threat to humans

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