An important step towards completing the rheumatoid arthritis cycle

In the previous issue of Arthritis Research & Therapy data are presented showing that circulating immune complexes containing citrullinated fibrin(ogen) are present in anti-citrullinated protein antibody-positive rheumatoid arthritis patients, and that such immune complexes co-localize with complement factor C3 in the rheumatoid synovium. These results corroborate the idea that citrullination is intimately involved in the pathophysiology of rheumatoid arthritis and complete our model (the rheumatoid arthritis cycle) for the development and chronic nature of this disease.

• Publication year

  2008

• Venue

  Arthritis Research & Therapy

• Publication date

  2008-09-19

• Fields of study

  Medicine

• Identifiers
  DOI 10.1186/ar2504PMID 18828887PMCID 2592789
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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