The Effect of a Computer-Assisted Cognitive Remediation on Improving Cognitive Functions in Patients with Schizophrenia: A Before-After Study

Background: Cognitive impairment is a chronic and disabling manifestation of schizophrenia. Objectives: This before-after study was conducted to examine the effect of a short course computer-assisted cognitive remediation on improving cognitive functions of patients with schizophrenia. Materials and Methods: Twenty patients with schizophrenia were enrolled into the study. The intervention consisted of 10 onehour sessions held 2-3 times a week, using the Cogpack software that includes tasks to improve attention, memory, and executive function. The patients’ cognitive functioning was assessed before and after the remediation, using tests in the CANTAB battery, including stop signal task (SST) and choice reaction time (CRT) to assess attention levels, pattern recognition memory (PRM) and Paired associate learning (PAL) to examine memory, and stocking of Cambridge (SOC) and intra-extra dimensional task (IED) to evaluate executive function. Results: IED and SOC revealed a statistically significant improvement in executive function after the intervention. PAL revealed a significant improvement in memory functioning in most aspects after the intervention, while PRM did not. CRT showed a significant improvement in some aspects of attention and concentration after the intervention, while SST did not. Conclusions: This before-after study revealed that a relatively short course of a computer-assisted cognitive remediation can be applied to improve several aspects of cognitive functioning in patients with schizophrenia. A randomized controlled trial is required to establish the effectiveness of the intervention.

• Publication year

  2016

• Venue

  Iranian journal of psychiatry and behavioral sciences

• Publication date

  2016-10-24

• Fields of study

  Medicine, Computer Science, Psychology

• Identifiers
  DOI 10.17795/IJPBS-5132
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Kaplan & Sadock's synopsis of psychiatry : behavioral science/clinical psychiatry

  2014cited by this paper
• Cognitive remediation for schizophrenia: current status, biological correlates and predictors of response

  2012cited by this paper
• A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia.

  2011cited by this paper
• THE EFFICACY OF GROUP COGNITIVE-REMEDIATION THERAPY FOR PATIENTS WITH SCHIZOPHRENIA WITH LONGITUDINAL COURSE

  2011influential reference
• Cognitive Remediation for Psychological Disorders: Therapist Guide

  2009cited by this paper
• Computerised Assessment of Visuo-spatial Cognition in Schizophrenia - An Exploratory Meta-analysis of CANTAB Findings

  2008cited by this paper
• Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modelling

  2007cited by this paper
• Cognitive remediation therapy for outpatients with chronic schizophrenia: a controlled and randomized study.

  2006cited by this paper
• Computerized cognitive remediation improves verbal learning and processing speed in schizophrenia.

  2005cited by this paper
• Cognitive predictors of psychosocial functioning outcome in schizophrenia: a follow-up study of subjects participating in a rehabilitation program.

  2005influential reference
• Reliability and validity of DSM-IV axis V.

  2000cited by this paper
• Semantic priming in schizophrenia: an examination of spreading activation using word pronunciation and multiple SOAs.

  1996cited by this paper
• Integrated Psychological Therapy for Schizophrenic Patients (IPT)

  1996cited by this paper
• integrated Psychological Therapy for Schizophrenic Patients (ipt) .

  1996cited by this paper
• THE MEASUREMENT OF ADULT INTELLIGENCE

  1939cited by this paper

• Acceptability and impact of computerised cognitive training on mental health and cognitive skills in schizophrenia: a double-blind controlled trial

  2025cites this paper
• Eficacia del programa gradior para la estimulación cognitiva de personas con alzheimer (Effectiveness of Gradior software and cognitive stimulation in people with alzheimer’s disease)

  2022cites this paper
• Title: A Short Course Computer-Based Cognitive Remediation in Patients With Schizophrenia Spectrum Disorders: A Randomized Clinical Trial

  2021cites this paper
• A Short Course Computer-assisted Cognitive Remediation in Patients with Schizophrenia Spectrum Disorders: A Randomized Clinical Trial

  2021cites this paper