Severe Sepsis and Septic Shock Associated with Chikungunya Virus Infection, Guadeloupe, 2014

During a 2014 outbreak, 450 patients with confirmed chikungunya virus infection were admitted to the University Hospital of Pointe-à-Pitre, Guadeloupe. Of these, 110 were nonpregnant adults; 42 had severe disease, and of those, 25 had severe sepsis or septic shock and 12 died. Severe sepsis may be a rare complication of chikungunya virus infection.

• Publication year

  2016

• Venue

  Emerging Infectious Diseases

• Publication date

  2016-05-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.3201/eid2205.151449PMID 27088710PMCID 4861514
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• Severe sepsis may be a rare complication of chikungunya virus infection.

  Confidence 0.90

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• Of the severe adult cases, 25 had severe sepsis or septic shock and 12 died.

  Confidence 0.97

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• Among 110 nonpregnant adults, 42 had severe disease.

  Confidence 0.96

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• 450 patients with confirmed chikungunya virus infection were admitted to the University Hospital of Pointe-à-Pitre in Guadeloupe during the 2014 outbreak.

  Confidence 0.98

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review

• 2014 outbreak

  event

  The epidemic period in 2014 during which the hospitalized chikungunya cases were observed.

  Aliases: outbreak

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• chikungunya virus infection

  infectious disease

  An infection caused by chikungunya virus, used here as the confirmed diagnosis in the hospitalized cohort.

  Aliases: CHIKV infection

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• death

  outcome

  A fatal outcome reported among the severe adult cases in the cohort.

  Aliases: died, mortality

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• guadeloupe

  location

  The Caribbean island territory where the 2014 outbreak occurred.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• nonpregnant adults

  patient group

  Adult patients without pregnancy status who were included in the severe-disease subset analyzed in the report.

  Aliases: adult nonpregnant patients

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• septic shock

  clinical syndrome

  A shock state associated with sepsis that was recorded among the severe adult cases.

  Aliases: shock

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• severe disease

  clinical condition

  A clinically severe form of illness among the hospitalized chikungunya patients.

  Aliases: severe chikungunya disease

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• severe sepsis

  clinical syndrome

  A severe systemic infectious syndrome considered among the serious complications in affected adults.

  Aliases: sepsis

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review
• university hospital of pointe-à-pitre

  hospital

  The hospital in Guadeloupe where the confirmed chikungunya cases were admitted.

  Aliases: Pointe-à-Pitre University Hospital

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAnonymous (12632b8b5f) reviewq (76h6bfydm6) review

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