Antigen processing and presentation: Evolution from a bird's eye view☆

Highlights ► Single MHC molecules in chicken versus multiple MHC molecules in mammals. ► Single MHC molecules in chicken strongly determine immune response. ► Single chicken class I due to co-evolution with polymorphic antigen processing genes. ► Co-evolution in chicken MHC due to different genomic organisation. ► Chicken MHC like ancestral MHC, with inversion in lineage to mammals.

• Publication year

  2013

• Venue

  Molecular Immunology

• Publication date

  2013-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.molimm.2012.10.030PMID 23182425PMCID 3878743
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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