Understanding bovine trypanosomiasis and trypanotolerance: the promise of functional genomics.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Veterinary Immunology and Immunopathology

• Publication date

  2005-05-15

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/J.VETIMM.2005.02.004PMID 15808304
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Zebu-taurine variation in Y chromosomal DNA: a sensitive assay for genetic introgression in west African trypanotolerant cattle populations.

  2009cited by this paper
• Statistical design and the analysis of gene expression microarray data.

  2007cited by this paper
• Construction and application of a bovine immune-endocrine cDNA microarray.

  2004cited by this paper
• BLAST: at the core of a powerful and diverse set of sequence analysis tools

  2004cited by this paper
• Mechanisms for the elimination of potentially lytic complement-fixing variable surface glycoprotein antibody-complexes inTrypanosoma brucei

  2004cited by this paper
• Design and Analysis of DNA Microarray Investigations

  2004cited by this paper
• Generation of EST and cDNA Microarray Resources for the Study of Bovine Immunobiology*

  2003cited by this paper
• Antigenic variation and the African trypanosome genome.

  2003cited by this paper
• TM4: a free, open-source system for microarray data management and analysis.

  2003cited by this paper
• Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense.

  2003cited by this paper
• Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N'Dama and susceptible East African Boran cattle

  2003cited by this paper
• Identification of mechanisms of natural resistance to African trypanosomiasis in cattle.

  2002cited by this paper
• During Trypanosoma cruzi Infection CD1d-Restricted NK T Cells Limit Parasitemia and Augment the Antibody Response to a Glycophosphoinositol-Modified Surface Protein

  2002cited by this paper
• Design issues for cDNA microarray experiments

  2002cited by this paper
• Gene Expression Profiling of Peripheral Blood Mononuclear Cells from Cattle Infected with Mycobacterium paratuberculosis

  2002cited by this paper
• African Pastoralism: Genetic Imprints of Origins and Migrations

  2002cited by this paper
• Comparison of microarray designs for class comparison and class discovery

  2002cited by this paper
• Investing in animal health research to alleviate poverty.

  2002cited by this paper
• Bioinformatics and high throughput approach to create genomic resources for the study of bovine immunobiology.

  2002cited by this paper
• Statistical design and the analysis of gene expression microarray data.

  2001cited by this paper
• Immunisation of cattle with cysteine proteinases of Trypanosoma congolense: targetting the disease rather than the parasite.

  2001cited by this paper
• Trypanosomiasis control.

  2001cited by this paper
• Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays.

  2000cited by this paper
• Geographic distribution and frequency of a taurine Bos taurus and an indicine Bos indicus Y specific allele amongst sub‐Saharan African cattle breeds

  2000cited by this paper
• Impacts of trypanosomiasis on African agriculture.

  1999cited by this paper
• MEASURING THE COSTS OF AFRICAN ANIMAL TRYPANOSOMOSIS, THE POTENTIAL BENEFITS OF CONTROL AND RETURNS TO RESEARCH

  1999cited by this paper
• Breeding for Disease Resistance in Farm Animals

  1999cited by this paper
• The extended protein kinase C superfamily.

  1998cited by this paper
• A field guide for the diagnosis, treatment and prevention of African animal trypanosomosis

  1998cited by this paper
• Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus).

  1997cited by this paper
• The role of anti‐variable surface glycoprotein antibody responses in bovine trypanotolerance

  1996cited by this paper
• Signal transduction of phagocytosis.

  1995cited by this paper
• Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?

  1995cited by this paper
• Antibody responses to a 33 kDa cysteine protease of Trypanosoma congolense: relationship to ‘trypanotolerance’ in cattle

  1993cited by this paper
• Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection.

  1992cited by this paper
• Characterization and measurement of CD5+ B cells in normal and Trypanosoma congolense‐infected cattle

  1992cited by this paper
• Inhibition of macrophage protein kinase C-mediated protein phosphorylation by Leishmania donovani lipophosphoglycan.

  1992cited by this paper
• Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection

  1992cited by this paper
• Susceptibility of N'Dama and Boran cattle to sequential challenges with tsetse‐transmitted clones of Trypanosoma congolense

  1991influential reference
• Susceptibility of N'Dama and Boran cattle to tsetse‐transmitted primary and rechallenge infections with a homologous serodeme of Trypanosoma congolense

  1991cited by this paper
• Trypanosoma congolense: complement independent immobilization by a monoclonal antibody.

  1990cited by this paper
• Peripheral blood leucocytes subpopulation dynamics during Trypanosoma congolense infection in Boran and N'Dama cattle: an analysis using monoclonal antibodies and flow cytometry

  1987influential reference
• The role of antibody in natural resistance to African trypanosomiasis.

  1987cited by this paper
• Potential value of localized skin reactions (chancres) induced by Trypanosoma congolense transmitted by Glossina morsitans centralis for the analysis of metacyclic trypanosome populations

  1987cited by this paper
• Isolation and subfractionation of human peripheral blood mononuclear cells (PBMC) by density gradient centrifugation on Percoll.

  1984cited by this paper
• Cytotoxicity of monoclonal antibodies to Trypanosoma brucei.

  1984cited by this paper
• Resistance of cattle to tsetse-transmitted challenge with Trypanosoma brucei or Trypanosoma congolense after spontaneous recovery from syringe-passaged infections

  1984cited by this paper
• Phagocytosis of antibody-sensitized Trypanosoma brucei in vitro by bovine peripheral blood monocytes.

  1983cited by this paper
• Host susceptibility to African trypanosomiasis: trypanotolerance.

  1982cited by this paper
• A comparative evaluation of the parasitological techniques currently available for the diagnosis of African trypanosomiasis in cattle.

  1982cited by this paper
• The dynamics of the cellular reactions elicited in the skin of goats by Glossina morsitans morsitans infected with Trypanosoma (Nannomonas) congolense or T. (Duttonella) vivax.

  1981cited by this paper
• African trypanosomes.

  1981cited by this paper
• Bovine immune response to African trypanosomes: specific antibodies to variable surface glycoproteins of Trypanosoma brucei

  1981cited by this paper
• The immune response of zebu cattle infection with Trypanosoma congolense and T. vivax.

  1976cited by this paper
• Sleeping sickness survey in the Serengeti area (Tanzania) 1971. I. Examination of large mammals for trypanosomes.

  1973cited by this paper

• Functional genomics of trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense across multiple time points and tissues

  2025cites this paper
• Epidemiology and economic impact of bovine trypanosomosis in Jawi District, Northwest Ethiopia

  2025influential citation
• First detection of Trypanosoma vivax in dairy cattle from the northwest region of Minas Gerais, Brazil

  2023cites this paper
• The COMBAT project: controlling and progressively minimizing the burden of vector-borne animal trypanosomosis in Africa

  2022cites this paper
• Deciphering the Molecular Mechanism Underlying African Animal Trypanosomiasis by Means of the 1000 Bull Genomes Project Genomic Dataset

  2022cites this paper
• A one health investigation of pathogenic trypanosomes of cattle in Malawi.

  2021cites this paper
• Computational Identification of Master Regulators Influencing Trypanotolerance in Cattle

  2021cites this paper
• The impacts of diabetes mellitus on the pathogenicity of trypanosomosis in rodents

  2020cites this paper
• Genome Analysis Reveals Genetic Admixture and Signature of Selection for Productivity and Environmental Traits in Iraqi Cattle

  2019cites this paper
• Parasitological and immunological evaluation of cattle experimentally infected with Trypanosoma vivax.

  2018cites this paper
• African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

  2018cites this paper
• Characterization of Trypanosomes and Determination of Trypanosome Immunogenic Proteins in Cattle in Ghana

  2018cites this paper
• Characterisation of the Djallonke Sheep Breed in Ghana using Molecular Markers

  2017influential citation
• An Overview of Trypanosoma brucei Infections: An Intense Host–Parasite Interaction

  2016cites this paper
• Tropically adapted cattle of Africa: perspectives on potential role of copy number variations.

  2016cites this paper
• Combatting African Animal Trypanosomiasis (AAT) in livestock: The potential role of trypanotolerance.

  2016influential citation
• Effect of Peste des petits ruminants Vaccination on Clinico-haematological Parameters of West African Dwarf Sheep Experimentally Infected with Trypanosoma congolense

  2016cites this paper
• Investigation into the major surface proteases of African trypanosomes.

  2016cites this paper
• Genetic resistance: tolerance to vector-borne diseases and the prospects and challenges of genomics.

  2015cites this paper
• Exploiting genetic variation to discover genes involved in important disease phenotypes.

  2015cites this paper
• The effects of short term dietary restriction on haematological responses and leukocyte gene expression of anovulatory and ovulatory beef heifers.

  2015cites this paper
• The Quality of Methods Reporting in Parasitology Experiments

  2014cites this paper
• Data Mining Techniques in Grid Computing Environments

  2014cites this paper
• African Trypanosomiasis as Paradigm for Involvement of the Mononuclear Phagocyte System in Pathogenicity During Parasite Infection

  2014cites this paper
• African trypanosome control in the insect vector and mammalian host.

  2014cites this paper
• Trypanosomosis: a priority disease in tsetse-challenged areas of Burkina Faso

  2013cites this paper
• Functional expression of Trypanosoma congolense pyroglutamyl peptidase type 1 and development of reverse genetics tools.

  2013cites this paper
• Treatment Alleviates A Glycosylphosphatidylinositol-Based

  2013cites this paper
• Virulence in African Trypanosomes: Genetic and Molecular Approaches

  2013cites this paper
• Genomics and Potential Downstream Applications in the Developing World

  2012cites this paper
• Time Course of Gene Expression Profiling in the Liver of Experimental Mice Infected with Echinococcus multilocularis

  2011cites this paper
• Trypanosome genetics: populations, phenotypes and diversity.

  2011cites this paper
• The effects of diabetes mellitus on the pathogenicity of trypanosomosis in rats

  2011cites this paper
• Developing optimized cattle breeding schemes based on the demands and opportunities of poor livestock keepers in Eastern Africa with a special focus on Trypanosomiasis

  2010cites this paper
• Trypanosoma vivax Infections: Pushing Ahead with Mouse Models for the Study of Nagana. I. Parasitological, Hematological and Pathological Parameters

  2010cites this paper
• Etude des interactions hôte/parasite chez l’huître plate Ostrea edulis et son parasite Bonamia ostreae

  2010cites this paper
• Experimental Trypanosoma brucei infection at immediate post partum period: effects on dam and the offspring

  2010cites this paper
• Epidemiology, control and potential insect vectors of Trypanosoma evansi (surra) in village livestock in southern Philippines

  2010cites this paper
• Development of tools to improve the detection of Trypanosoma evansi in Australia

  2009cites this paper
• Human African trypanosomes: challenges posed to the human immune system.

  2009cites this paper
• Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility

  2009influential citation
• Review Paper: Gene Expression Profiling in Veterinary and Human Medicine: Overview of Applications and Proposed Quality Control Practices

  2009cites this paper
• Developing Optimized Cattle Breeding Schemes based on the Demands and Opportunities of Poor Livestock Keepers in Eastern Africa with a special Focus on Trypanosomiasis

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• Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle.

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• A review of gene expression profiling of human embryonic stem cell lines and their differentiated progeny.

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• Understanding the role of monocytic cells in liver inflammation using parasite infection as a model.

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• Host genetics in African trypanosomiasis.

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• Analysis of gene expression profiles in the liver and spleen of mice infected with Trypanosoma evansi by using a cDNA microarray

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  2007cites this paper
• STATE OF THE ART IN THE MANAGEMENT OF ANIMAL GENETIC RESOURCES

  2007cites this paper
• Gene expression profiling of peripheral mononuclear cells in lame dairy cows with foot lesions.

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• A systematic strategy for large-scale analysis of genotype–phenotype correlations: identification of candidate genes involved in African trypanosomiasis

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• Development and validation of a bovine macrophage specific cDNA microarray

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• Human African trypanosomiasis: connecting parasite and host genetics.

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• Current Research Status for Economically Important Candidate Genes and Microarray Studies in Cattle

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• Gene expression profiling in a mouse model for African trypanosomiasis

  2006cites this paper
• The expanding role of microarrays in the investigation of macrophage responses to pathogens.

  2005cites this paper
• Current Awareness on Comparative and Functional Genomics

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