Isolation of cells that retain differentiated functions in vitro: properties of clonally isolated type II alveolar pneymonocytes.

We have isolated byclonal culture techniques a diploid cell strain (L-2) from adult rat lung. These cells appear to retain differentiated functions that are present in type II alveolar epithelial cells of intact lung. The L-2 cells are diploid, epithelial cells, they contain osmiophilic lamellar bodies in their cytoplasm and they synthesize lecithin by the same de novo pathways as whole lung. ImagesFIGURE 1.

• Publication year

  1976

• Venue

  Environmental Health Perspectives

• Publication date

  1976-08-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1289/EHP.761683PMID 797569PMCID 1475225
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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