THE EFFECT OF TUBERCLE BACILLI ON THE POLYMORPHONUCLEAR LEUCOCYTES OF NORMAL ANIMALS

A description is given of a slide cell whereby the rate of migration of very small amounts of leucocytes can be followed and measured. The migration of polymorphonuclear leucocytes was found to be inhibited by virulent tubercle bacilli pathogenic for the class of animal (mammal or bird) from which the leucocytes were obtained; it was not affected by the avirulent variants of these microorganisms, or by bacilli pathogenic for animals of the other class. Tests failed to disclose that the inhibition of leucocytic migration resulted from any gross damage caused by the bacilli to the leucocytes.

• Publication year

  1950

• Venue

  Journal of Experimental Medicine

• Publication date

  1950-03-31

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/JEM.91.4.381PMID 19871714PMCID 2135969
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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