Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Neuron

• Publication date

  2013-12-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.neuron.2013.10.007PMID 24360543
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• EphrinB3/EphA4-mediated guidance of ascending and descending spinal tracts.

  2013cited by this paper
• BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord

  2012cited by this paper
• RabGDI controls axonal midline crossing by regulating Robo1 surface expression

  2012cited by this paper
• Propriospinal pathways in the dorsal horn (laminae I-IV) of the rat lumbar spinal cord.

  2012cited by this paper
• Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

  2012cited by this paper
• SnapShot: spinal cord development.

  2011cited by this paper
• VEGF Signaling through Neuropilin 1 Guides Commissural Axon Crossing at the Optic Chiasm

  2011cited by this paper
• Further tales of the midline.

  2011cited by this paper
• VEGF mediates commissural axon chemoattraction through its receptor Flk1.

  2011cited by this paper
• Neuronal circuitry for pain processing in the dorsal horn

  2010cited by this paper
• A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

  2010cited by this paper
• Collaborative and Specialized Functions of Robo1 and Robo2 in Spinal Commissural Axon Guidance

  2010cited by this paper
• Motor and Dorsal Root Ganglion Axons Serve as Choice Points for the Ipsilateral Turning of dI3 Axons

  2010cited by this paper
• Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling

  2009cited by this paper
• Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1

  2009influential reference
• Unidirectional startle responses and disrupted left–right co‐ordination of motor behaviors in robo3 mutant zebrafish

  2009cited by this paper
• Specificity and Sufficiency of EphB1 in Driving the Ipsilateral Retinal Projection

  2009cited by this paper
• Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms

  2008cited by this paper
• A molecular program for contralateral trajectory: Rig-1 control by LIM homeodomain transcription factors.

  2008cited by this paper
• Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.

  2008cited by this paper
• Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons

  2006cited by this paper
• A role for Nr-CAM in the patterning of binocular visual pathways.

  2006cited by this paper
• Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes

  2005influential reference
• Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn

  2005cited by this paper
• Mutations in a Human ROBO Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis

  2004cited by this paper
• Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding.

  2004cited by this paper
• The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.

  2004cited by this paper
• `Eph'ective signaling: forward, reverse and crosstalk

  2003cited by this paper
• Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.

  2003cited by this paper
• Zic2 patterns binocular vision by specifying the uncrossed retinal projection.

  2003cited by this paper
• Role of EphA4 and EphrinB3 in Local Neuronal Circuits That Control Walking

  2003cited by this paper
• Zic2 is required for neural crest formation and hindbrain patterning during mouse development.

  2003cited by this paper
• Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system.

  2002cited by this paper
• Mechanisms and functions of eph and ephrin signalling

  2002cited by this paper
• Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord.

  2002cited by this paper
• Pathfinding and error correction by retinal axons: the role of astray/robo2.

  2002cited by this paper
• The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord.

  2002cited by this paper
• Proprioceptor pathway development is dependent on Math1.

  2001cited by this paper
• astray, a Zebrafish roundabout Homolog Required for Retinal Axon Guidance

  2001cited by this paper
• Development of the human spinal cord : an interpretation based on experimental studies in animals

  2001cited by this paper
• Zic2 regulates the kinetics of neurulation.

  2000cited by this paper
• Lbx1 is required for muscle precursor migration along a lateral pathway into the limb.

  2000cited by this paper
• Neuronal specification in the spinal cord: inductive signals and transcriptional codes

  2000cited by this paper
• Retinal Ganglion Cell Axon Guidance in the Mouse Optic Chiasm: Expression and Function of Robos and Slits

  2000cited by this paper
• Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.

  1999cited by this paper
• Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching.

  1999cited by this paper
• Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired

  1998cited by this paper
• Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube

  1998cited by this paper
• Progenitors of dorsal commissural interneurons are defined by MATH1 expression.

  1998cited by this paper
• The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an essential role for Zic genes in body pattern formation.

  1997cited by this paper
• Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.

  1996cited by this paper
• Neurogenesis of ascending supraspinal projection neurons: ipsi- versus contralateral projections.

  1991cited by this paper
• Neurobiology: Cross-section of the spinal cord

  1984cited by this paper
• The development of the cervical spinal cord of the mouse embryo. II. A Golgi analysis of sensory, commissural, and association cell differentiation

  1984cited by this paper
• Cross-section of the spinal cord.

  1984cited by this paper
• Some effects of disconnecting the cerebral hemispheres.

  1982cited by this paper
• Neuronal and synaptic arrangement in the substantia gelatinosa rolandi

  1964cited by this paper

• ZIC2 drives colorectal cancer progression by regulating QPRT-mediated cell migration

  2026cites this paper
• Ontogeny of the spinal cord dorsal horn

  2026cites this paper
• Temporal control of axonal floor plate crossing through a combination of incoherent feedforward and feedback loops of gene regulatory network regulating Robo3 expression

  2025cites this paper
• Molecular landscape, subtypes, and therapeutic vulnerabilities of central nervous system solitary fibrous tumors

  2025cites this paper
• Novel insights into the mechanisms of growth cone dynamics during axon pathfinding.

  2025cites this paper
• Ontogeny of the spinal cord dorsal horn

  2025cites this paper
• From neural tube to spinal cord: The dynamic journey of the dorsal neuroepithelium.

  2024cites this paper
• ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial to mesenchymal transition in cranial neural crest lineage commitment

  2024cites this paper
• Novel aspects of signal processing in lamina I.

  2024cites this paper
• Genome binding properties of Zic transcription factors underlie their changing functions during neuronal maturation

  2024cites this paper
• EphA4 Mediates EphrinB1-Dependent Adhesion in Retinal Ganglion Cells

  2024cites this paper
• ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification

  2024cites this paper
• Neural progenitor–derived Apelin controls tip cell behavior and vascular patterning

  2024cites this paper
• Development of the Binocular Circuit

  2024cites this paper
• Genome binding properties of Zic transcription factors underlie their changing functions during neuronal maturation

  2024cites this paper
• Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture.

  2023cites this paper
• FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway

  2023cites this paper
• Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections.

  2023cites this paper
• Transcriptional Control of Axon Guidance at Midline Structures

  2022influential citation
• Editorial-Friedrich Bonhoeffer (1932-2021).

  2022cites this paper
• Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections

  2022influential citation
• Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding

  2022cites this paper
• Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin

  2021cites this paper
• Axonal Projection Patterns of the Dorsal Interneuron Populations in the Embryonic Hindbrain

  2021cites this paper
• Artesunate-induced Cellular Effects Are Mediated by Specific EPH Receptors and Ephrin Ligands in Breast Carcinoma Cells

  2021cites this paper
• Transcriptional regulation of neuronal identity

  2021cites this paper
• With the Permission of Microtubules: An Updated Overview on Microtubule Function During Axon Pathfinding

  2021cites this paper
• A protocol for in ovo electroporation of chicken and snake embryos to study forebrain development

  2021cites this paper
• A Zic2-regulated switch in a noncanonical Wnt/βcatenin pathway is essential for the formation of bilateral circuits

  2020cites this paper
• ZIC2 promotes cancer stem cell traits via up-regulating OCT4 expression in lung adenocarcinoma cells

  2020cites this paper
• Ephrin/Eph signaling in axon guidance

  2020cites this paper
• Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements.

  2019influential citation
• Shared and differential features of Robo3 expression pattern in amniotes

  2019cites this paper
• Roles of axon guidance molecules in neuronal wiring in the developing spinal cord

  2019cites this paper
• Commissural axon guidance in the developing spinal cord: from Cajal to the present day

  2019cites this paper
• Zic2 abrogates an alternative Wnt signaling pathway to convert axon attraction into repulsion

  2019influential citation
• Construction and reconstruction of brain circuits: normal and pathological axon guidance

  2019cites this paper
• Presynaptic inhibition of cutaneous afferents prevents chronic itch

  2019cites this paper
• Mechanistic characterization of ZIC2 function during brain patterning

  2019cites this paper
• Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels

  2018cites this paper
• Cranial Pair II: The Optic Nerves

  2018cites this paper
• Role of the Glycogen Synthase Kinase 3 for the Retinal Development and Homeostasis

  2018cites this paper
• Rodent Zic Genes in Neural Network Wiring.

  2018cites this paper
• Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.

  2018cites this paper
• Differential Expression Patterns of Eph Receptors and Ephrin Ligands in Human Cancers

  2018cites this paper
• The Robo3 receptor, a key player in the development, evolution, and function of commissural systems

  2017cites this paper
• Implication of retinal epha4 in refinement of collicular visual maps

  2017influential citation
• Identification of molecular markers distinguishing adult neural stem cells in the subventricular and subcallosal zones

  2017cites this paper
• Time‐Lapse Imaging and Cell Tracking of Migrating Cells in Slices and Flattened Telencephalic Vesicles

  2017cites this paper
• Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis.

  2017cites this paper
• Zic-Proteins Are Repressors of Dopaminergic Forebrain Fate in Mice and C. elegans

  2017cites this paper
• Guidance of retinal axons in mammals.

  2017cites this paper
• Corticospinal circuit plasticity in motor rehabilitation from spinal cord injury.

  2017cites this paper
• Spinal RacGAP α-Chimaerin Is Required to Establish the Midline Barrier for Proper Corticospinal Axon Guidance

  2017cites this paper
• Rostro-Caudal and Caudo-Rostral Migrations in the Telencephalon: Going Forward or Backward?

  2017cites this paper
• Recurrent DCC gene losses during bird evolution

  2017cites this paper
• The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells.

  2016cites this paper
• Mechanisms of ephrin–Eph signalling in development, physiology and disease

  2016cites this paper
• Regulation of axon guidance receptor expression and activity during neuronal morphogenesis

  2016cites this paper
• Context-Dependent Gait Choice Elicited by EphA4 Mutation in Lbx1 Spinal Interneurons.

  2016cites this paper
• Transient ipsilateral retinal ganglion cell projections to the brain: Extent, targeting, and disappearance

  2015cites this paper
• Zic2 Controls the Migration of Specific Neuronal Populations in the Developing Forebrain

  2015cites this paper
• Neurons in the lateral part of the lumbar spinal cord show distinct novel axon trajectories and are excited by short propriospinal ascending inputs

  2015cites this paper
• The Eph Receptor Family

  2015cites this paper
• Zic2 is an enhancer-binding factor required for embryonic stem cell specification

  2015cites this paper
• Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3

  2015cites this paper
• Axon Guidance Molecules and Neural Circuit Remodeling After Spinal Cord Injury

  2015cites this paper
• Connecting the Retina to the Brain

  2014influential citation
• Development and plasticity of commissural circuits: from locomotion to brain repair.

  2014cites this paper
• Transcription factors and effectors that regulate neuronal morphology

  2014influential citation
• Role of EphA4 in spinal circuits controlling locomotion

  2014cites this paper
• DEV110817 4667..4680

  2014influential citation
• Ephrin signalling in the developing nervous system.

  2014cites this paper
• EphrinB3/EphA4-mediated guidance of ascending and descending spinal tracts.

  2013cites this paper