Preferential amplification of the paternal allele of the N–myc gene in human neuroblastomas

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Nature Genetics

• Publication date

  1993-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/NG0693-191PMID 8102299
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N–myc amplification

  1993cited by this paper
• A complex single strand conformational polymorphism (SSCP) in the tumor necrosis factor receptor 2 (TNFR2) gene on chromosome 1p36.2.

  1993cited by this paper
• Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation.

  1993cited by this paper
• Wilms' tumor‐specific methylation pattern in 11p13 detected by PFGE

  1992cited by this paper
• Physical linkage of two mammalian imprinted genes, H19 and insulin–like growth factor 2

  1992cited by this paper
• Maternal but not paternal transmission of 15q11–13–linked nondeletion Angelman syndrome leads to phenotypic expression

  1992cited by this paper
• A DNA methylation imprint, determined by the sex of the parent, distinguishes the Angelman and Prader-Willi syndromes.

  1992cited by this paper
• Genetic analysis of genomic imprinting: an Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus.

  1992cited by this paper
• Parental origin of chromosomes involved in the translocation t(9;22)

  1992cited by this paper
• Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas.

  1992cited by this paper
• Isolation and structural analysis of a 1.2-megabase N-myc amplicon from a human neuroblastoma

  1992cited by this paper
• The polar-lethal Ovum mutant gene maps to the distal portion of mouse chromosome 11.

  1992cited by this paper
• Equivalent expression of paternally and maternally inherited WT1 alleles in normal fetal tissue and Wilms' tumours.

  1992cited by this paper
• Allele-specific hypermethylation of the retinoblastoma tumor-suppressor gene.

  1991cited by this paper
• Nonrandom distribution of N-myc oncogene genotypes in neuroblastoma.

  1991cited by this paper
• Uniparental paternal disomy in a genetic cancer-predisposing syndrome

  1991cited by this paper
• Neuroblastoma: clinical significance of genetic abnormalities.

  1990cited by this paper
• Genome imprinting, cellular mosaicism and carcinogenesis

  1990cited by this paper
• Preferential retention of paternal alleles in human retinoblastoma: evidence for genomic imprinting.

  1990cited by this paper
• Genomic imprinting: review and relevance to human diseases.

  1990cited by this paper
• Epigenetic control of transgene expression and imprinting by genotype-specific modifiers.

  1990cited by this paper
• Chromosomal destabilization during gene amplification

  1990cited by this paper
• Genetic imprinting suggested by maternal heterodisomy in nondeletion Prader-Willi syndrome.

  1989cited by this paper
• Maternal allele loss in Wilms' tumour.

  1989cited by this paper
• Molecular biology and genetics of human neuroblastoma.

  1989cited by this paper
• Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma

  1989cited by this paper
• Parental origin of mutations of the retinoblastoma gene

  1989cited by this paper
• Preferential germline mutation of the paternal allele in retinoblastoma

  1989cited by this paper
• Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome

  1989cited by this paper
• Genomic imprinting and genetic disorders in man.

  1989cited by this paper
• A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting.

  1989cited by this paper
• Epigenetic and genetic factors affect transgene methylation imprinting.

  1989cited by this paper
• The importance of circular DNA in mammalian gene amplification.

  1989cited by this paper
• Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: correlation with N-myc amplification.

  1989cited by this paper
• Recent progress in understanding mechanisms of mammalian DNA amplification.

  1989cited by this paper
• Principles and Practice of Pediatric Oncology

  1989cited by this paper
• A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting

  1989cited by this paper
• Double minute chromosomes can be produced from precursors derived from a chromosomal deletion

  1988cited by this paper
• AMPLIFIED ALLELE OF THE HUMAN N‐myc ONCOGENE IN NEUROBLASTOMAS

  1988cited by this paper
• Characterization of N-myc amplification units in human neuroblastoma cells

  1988cited by this paper
• Localized neuroblastoma treated by surgery: a Pediatric Oncology Group Study.

  1988cited by this paper
• Inheritance of allelic blueprints for methylation patterns.

  1988cited by this paper
• Restriction fragment length polymorphisms of the human N-myc gene: relationship to gene amplification.

  1987cited by this paper
• Genomic imprinting determines methylation of parental alleles in transgenic mice

  1987cited by this paper
• Degree of methylation of transgenes is dependent on gamete of origin

  1987cited by this paper
• Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors.

  1987cited by this paper
• A hypervariable repeated sequence on human chromosome 1p36

  1987cited by this paper
• Expression and function of CD4 in a murine T-cell hybridoma.

  1987cited by this paper
• Variable number of tandem repeat (VNTR) markers for human gene mapping.

  1987cited by this paper
• Expression and function of CD8 in a murine T cell hybridoma

  1987cited by this paper
• Human proto-oncogene N-myc encodes nuclear proteins that bind DNA

  1986cited by this paper
• Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage.

  1984cited by this paper
• Clinical Pediatric Oncology

  1978cited by this paper
• CELL-SURFACE CHARACTERISTICS IN HAIRY-CELL LEUKÆMIA

  1975cited by this paper

• MYC phase separation selectively modulates the transcriptome

  2024cites this paper
• A review of nemorosone: Chemistry and biological properties.

  2023cites this paper
• Crocin inhibits proliferation and induces apoptosis through suppressing MYCN expression in retinoblastoma

  2019cites this paper
• Neuroblastoma

  2018cites this paper
• MAPT (Tau) expression is a biomarker for an increased rate of survival in pediatric neuroblastoma

  2018cites this paper
• Identification of complex genomic rearrangements in cancers using CouGaR

  2017cites this paper
• Clinical Significance of Genes in the NeoTYPE Brain Tumor Profile

  2017cites this paper
• PD-L1, inflammation, non-coding RNAs, and neuroblastoma: Immuno-oncology perspective.

  2017cites this paper
• Identification & Evaluation of DNA Ligase Inhibitors: Predicting the Binding of Small Molecules to the DNA Binding Domain by Molecular Modeling

  2017cites this paper
• A miRNA catalogue and ncRNA annotation of the short-living fish Nothobranchius furzeri

  2017cites this paper
• miR‐34a inhibits the apoptosis of MDSCs by suppressing the expression of N‐myc

  2016cites this paper
• Berberine induces neuronal differentiation through inhibition of cancer stemness and epithelial-mesenchymal transition in neuroblastoma cells.

  2016cites this paper
• Clinical characteristics of infant neuroblastoma and a summary of treatment outcome.

  2016cites this paper
• Integrative Multi-omics Module Network Inference with Lemon-Tree

  2014cites this paper
• Genomic Imprinting and Uniparental Disomy

  2013cites this paper
• The Many Faces of MDM2 Binding Partners.

  2012cites this paper
• Retinoblastoma beyond RB1: recent advances in genetic biomarkers

  2010cites this paper
• Advances in Brief A Tumor Suppressor Gene on Chromosome Ip 32-pter Controls the Amplification of MYC Family Genes in Breast Cancer 1

  2006cites this paper
• Advances in Brief Search for Mutations and Examination of Allei ic Expression Imbalance of the p 73 Gene at Ip 36 . 33 in Human Lung Cancers 1

  2006cites this paper
• The Coamplification Pattern of the MYCN Amplicon Is an Invariable Attribute of Most MYCN-Amplified Human Neuroblastomas

  2006cites this paper
• Clinical value of alterations in p73 gene, related to p53 at 1p36, in human hepatocellular carcinoma.

  2004cites this paper
• Amplified MYCN in Human Neuroblastoma

  2002cites this paper
• Regulation of N-myc expression in development and disease.

  2002cites this paper
• Genetic parameters of neuroblastomas.

  2002cites this paper
• Chromosome bands 1p35–36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted

  2001cites this paper
• Analysis of genomic imprinting at 1p35-36 in neuroblastoma.

  2001cites this paper
• PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

  2001cites this paper
• Genomic defects and mRNA expression profiles in neuroblastoma

  2000cites this paper
• p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent

  1999cites this paper
• NEOPLASIA Loss of p 73 Gene Expression in Leukemias / Lymphomas Due to Hypermethylation

  1999cites this paper
• Genomic imprinting: concept and clinical consequences.

  1999cites this paper
• Genomic imprinting and cancer.

  1999cites this paper
• Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.

  1999cites this paper
• Localization of the gene coding for ROCK II/Rho kinase on human chromosome 2p24.

  1999cites this paper
• Lack of p73 mutations and late occurrence of p73 allelic deletions in melanoma tissues and cell lines

  1999cites this paper
• Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.

  1998cites this paper
• Neuroblastoma Cell Lines

  1998cites this paper
• Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers.

  1998cites this paper
• A catalogue of imprinted genes and parent-of-origin effects in humans and animals.

  1998cites this paper
• Genomic imprinting and carcinogenesis.

  1998cites this paper
• MYCN Is the only highly expressed gene from the core amplified domain in human neuroblastomas

  1998cites this paper
• Molecular and cellular pathology of intrinsic brain tumours

  1997cites this paper
• No preferential parent of origin for the isochromosome 17q in childhood primitive neuroectodermal tumor (medulloblastoma)

  1997cites this paper
• Biology and genetics of human neuroblastomas.

  1997cites this paper
• Loss of heterozygosity on chromosome 1 in human hepatoblastoma

  1996cites this paper
• Relaxation of imprinting in carcinogenesis.

  1996cites this paper
• Deletion of 1p36 in childhood endodermal sinus tumors by two-color fluorescence in situ hybridization: a pediatric oncology group study.

  1996cites this paper
• The role of DNA methylation in cancer genetic and epigenetics.

  1996cites this paper
• Genetic clinical markers of human neuroblastoma with special reference to N-myc oncogene: amplified or not amplified?--An overview.

  1996cites this paper
• Deletion of Ip36 in childhood endodermal sinus tumors by two‐color fluorescence in situ hybridization: A pediatric oncology group study

  1996cites this paper
• Genetic Abnormality at the 1p32 Locus in Metastasis of Lung Cancer.

  1996cites this paper
• Parental imprinting and human disease.

  1996cites this paper
• Report of the second international workshop on human chromosome 1 mapping 1995.

  1996cites this paper
• Genomic imprinting in tumours.

  1996cites this paper
• Genomic imprinting: significance in development and diseases and the molecular mechanisms.

  1996cites this paper
• Neuroblastomas presenting in the first year of life: epidemiological differences from those presenting at older ages.

  1996cites this paper
• Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus

  1996cites this paper
• Genomic instability in Ip and human malignancies

  1996cites this paper
• THE ROLE OF DNA METHYLATION IN CANCER GENETICS AND EPIGENETICS

  1996cites this paper
• 1p36: every subband a suppressor?

  1995cites this paper
• Maintenance of normal imprinting of H19 and IGF2 genes in neuroblastoma.

  1995cites this paper
• Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification.

  1995cites this paper
• Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma.

  1995cites this paper
• Balanced translocation in a neuroblastoma patient disrupts a cluster of small nuclear RNA UI and tRNA genes in chromosomal band Ip36

  1995cites this paper
• Characterisation of the chromosome breakpoints in a patient with a constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12) and neuroblastoma.

  1995cites this paper
• Cell cycle-related protein kinases and T cell death.

  1995cites this paper
• Are ABL and BCR imprinted? No definitive answers, but more questions.

  1995cites this paper
• Deletion of chromosome 1p loci and microsatellite instability in neuroblastomas analyzed with short-tandem repeat polymorphisms.

  1995cites this paper
• Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.

  1995cites this paper
• N-MYC Oncogene Amplification: A Consequence of Genomic Instability in Human Neuroblastoma

  1995cites this paper
• Genomic imprinting and cancer.

  1995cites this paper
• Genetics of embryonal tumours of childhood: retinoblastoma, Wilms' tumour and neuroblastoma.

  1995cites this paper
• Genomic imprinting: mechanism and role in human pathology.

  1994cites this paper
• Diagnosis and the new genetics.

  1994cites this paper
• A tumor suppressor gene on chromosome 1p32-pter controls the amplification of MYC family genes in breast cancer.

  1994cites this paper
• Molecular biology primer for the pediatric pathologist.

  1994cites this paper
• Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma

  1994cites this paper
• Molecular genetic analysis of a constitutional chromosome translocation in a patient with ganglioneuroblastoma.

  1994cites this paper
• Book Review: Embryo Experimentation. Ethical, Legal, and Social Issues

  1994cites this paper
• Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity.

  1994cites this paper
• Genomic imprinting and gene activation in cancer

  1993cites this paper
• Autosomal imbalance syndromes: genetic interactions and the origin of congenital malformations in aneuploidy syndromes.

  1993cites this paper
• A study of allelic imbalance in human breast cancer

  1993cites this paper
• Deletion of Chromosome ip Loci and Microsatellite Instability in Neuroblastomas Analyzed with Short-Tandem Repeat Polymorphisms 1

  year unknowncites this paper