Four cases of facial discoid lupus erythematosus successfully treated with topical pimecrolimus or tacrolimus.

Discoid lupus erythematosus (DLE), which is a cutaneous form of lupus erythematosus (LE), is generally refractory to a wide range of topical or systemic therapies. Although the main treatment option for DLE is topical steroids, it is often ineffective or likely to produce long-term side effects. New drugs, including tacrolimus and pimecrolimus, have been developed to overcome the adverse effects of steroids and treat the lesions of DLE for a prolonged period. We herein report 4 cases of facial DLE successfully treated with therapeutic adjuvants, topical tacrolimus or pimecrolimus.

• Publication year

  2010

• Venue

  Annals of Dermatology

• Publication date

  2010-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.5021/ad.2010.22.3.307PMID 20711267PMCID PMC2917684
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Orphanet Journal of Rare Diseases BioMed Central Review

  2006cited by this paper
• Pimecrolimus 1% cream for the treatment of discoid lupus erythematosus.

  2005cited by this paper
• 0.1% tacrolimus ointment in the treatment of discoid lupus erythematosus.

  2005cited by this paper
• Pimecrolimus 1% cream for cutaneous lupus erythematosus.

  2004cited by this paper
• 0.1% Tacrolimus ointment in a patient with subacute cutaneous lupus erythematosus

  2004cited by this paper
• Treatment of chronic discoid lupus erythematosus with topical tacrolimus.

  2004cited by this paper
• Cutaneous Lupus Erythematosus

  2003cited by this paper
• Successful treatment of anogenital lichen sclerosus with topical tacrolimus.

  2003cited by this paper
• Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus

  2003influential reference
• Topical tacrolimus for repigmentation of vitiligo.

  2002cited by this paper
• Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents.

  2002cited by this paper
• The effect of topical tacrolimus on severe recalcitrant chronic discoid lupus erythematosus

  2002influential reference
• Topical FK506 (tacrolimus) therapy for facial erythematous lesions of cutaneous lupus erythematosus and dermatomyositis.

  2002cited by this paper
• Can morbidity and mortality of SLE be improved?

  2002cited by this paper
• First experience of topical SDZ ASM 981 in children with atopic dermatitis

  2001cited by this paper
• A novel anti‐inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: in vitro pharmacology

  1999cited by this paper
• Tacrolimus: the drug for the turn of the millennium?

  1999cited by this paper
• A short-term trial of tacrolimus ointment for atopic dermatitis. European Tacrolimus Multicenter Atopic Dermatitis Study Group.

  1997cited by this paper
• Systemic lupus erythematosus.

  1992cited by this paper
• TEXTBOOK OF GYNAECOLOGY

  1953cited by this paper

• Oral Discoid Lupus Erythematosus : A Case Effectively Managed and Differentiated with other Overlapping Diseases

  2018cites this paper
• A 13-year-old girl with a linear dark patch on her forehead: A case of scleroderma en coup de sabre in a child with skin of color presenting with a bruise-like appearance

  2018cites this paper
• Use and Misuse of Topical Corticosteroids in Hair and Scalp Disorders

  2018cites this paper
• Intense Pulsed Light and Q-Switched 1,064-nm Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment for the Scarring Lesion of Discoid Lupus Erythematosus

  2017cites this paper
• A Randomized, Double-Blinded Placebo Controlled Crossover Study Evaluating 0.03% Tacrolimus Ointment Monotherapy in the Treatment of Discoid Lupus Erythematosus in Dogs

  2017cites this paper
• Discoid lupus erythematosus: First clue to autoimmune haemolytic anaemia in a child

  2016cites this paper
• Tacrolimus 0.03% ointment in labial discoid lupus erythematosus: A randomized, controlled clinical trial

  2015cites this paper
• Treatment of Scarring Alopecia in Discoid Variant of Chronic Cutaneous Lupus Erythematosus With Tacrolimus Lotion, 0.3.

  2015cites this paper
• Topical Calcineurin Inhibitors: An Update on Their Use in Cutaneous Lupus Erythematosus

  2011cites this paper
• Update on the use of topical calcineurin inhibitors in cutaneous lupus erythematosus

  2011influential citation
• Disorders of Hair

  2010cites this paper