Time‐dependent traction force microscopy for cancer cells as a measure of invasiveness

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Cytoskeleton

• Publication date

  2013-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/cm.21100PMID 23444002
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Spatial coordination between cell and nuclear shape within micropatterned endothelial cells

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• 3D Traction Forces in Cancer Cell Invasion

  2012cited by this paper
• Cellular Traction Stresses Increase with Increasing Metastatic Potential

  2012influential reference
• Unravelling cerebellar pathways with high temporal precision targeting motor and extensive sensory and parietal networks

  2012cited by this paper
• Inverse problems for the determination of traction forces by cells on a substrate: a comparison of two methods

  2012cited by this paper
• Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces

  2011cited by this paper
• ImageJ, U.S. National Institutes of Health, Bethesda, Maryland, USA

  2011cited by this paper
• An in vitro correlation of mechanical forces and metastatic capacity

  2011cited by this paper
• Spatiotemporal constraints on the force-dependent growth of focal adhesions.

  2011influential reference
• Initial dynamics of cell spreading are governed by dissipation in the actin cortex.

  2011cited by this paper
• Optimization of traction force microscopy for micron-sized focal adhesions

  2010cited by this paper
• 4D traction force microscopy reveals asymmetric cortical forces in migrating Dictyostelium cells.

  2010cited by this paper
• Tumor cell/endothelial cell tight contact upregulates endothelial adhesion molecule expression mediated by NFkappaB: differential role of the shear stress.

  2010cited by this paper
• Force transmission in migrating cells

  2010cited by this paper
• Breakdown of cell-collagen networks through collagen remodeling

  2010cited by this paper
• Measurement of mechanical tractions exerted by cells in three-dimensional matrices

  2010influential reference
• Form and function in cell motility: from fibroblasts to keratocytes.

  2010cited by this paper
• Computational model for cell morphodynamics.

  2010cited by this paper
• Quantifying cellular traction forces in three dimensions

  2009cited by this paper
• Substrate topography induces a crossover from 2D to 3D behavior in fibroblast migration.

  2009cited by this paper
• Critical stresses for cancer cell detachment in microchannels

  2009cited by this paper
• A critical stress to detach cancer cells in microchannels

  2009cited by this paper
• Review: Rheological properties of biological materials

  2009cited by this paper
• The shape of motile cells.

  2009cited by this paper
• Traction patterns of tumor cells

  2009influential reference
• Propagation of mechanical stress through the actin cytoskeleton toward focal adhesions: model and experiment.

  2008cited by this paper
• Secreted CXCL1 Is a Potential Mediator and Marker of the Tumor Invasion of Bladder Cancer

  2008cited by this paper
• Anomalous dynamics of cell migration

  2008influential reference
• Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

  2008cited by this paper
• Mechanism of shape determination in motile cells

  2008cited by this paper
• Contractile forces in tumor cell migration.

  2008cited by this paper
• High resolution traction force microscopy based on experimental and computational advances.

  2008cited by this paper
• Traction forces and rigidity sensing regulate cell functions

  2008cited by this paper
• Lamellipodial actin mechanically links myosin activity with adhesion-site formation.

  2007cited by this paper
• Morphological analysis of tumor cell/endothelial cell interactions under shear flow.

  2007cited by this paper
• Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates

  2007cited by this paper
• Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration.

  2006cited by this paper
• Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis.

  2006cited by this paper
• Cellular Traction as an Inverse Problem

  2006cited by this paper
• Tissue Cells Feel and Respond to the Stiffness of Their Substrate

  2005influential reference
• ReviewCellular Motility Driven by Assembly and Disassembly of Actin Filaments to decipher

  2003cited by this paper
• Cellular motility driven by assembly and disassembly of actin filaments.

  2003cited by this paper
• Cells lying on a bed of microneedles: An approach to isolate mechanical force

  2003cited by this paper
• Traction fields, moments, and strain energy that cells exert on their surroundings.

  2002cited by this paper
• Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization.

  2002influential reference
• The relationship between force and focal complex development

  2002cited by this paper
• Influence of the microenvironment on the invasiveness of human bladder carcinoma cell lines.

  2002cited by this paper
• Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

  2001influential reference
• Influence of the microenvironment on invasiveness of human bladder carcinoma cell lines

  2001cited by this paper
• Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement

  2001cited by this paper
• Traction force microscopy of migrating normal and H-ras transformed 3T3 fibroblasts.

  2001influential reference
• Cell movement is guided by the rigidity of the substrate.

  2000influential reference
• Stresses at the cell-to-substrate interface during locomotion of fibroblasts.

  1999influential reference
• High resolution detection of mechanical forces exerted by locomoting fibroblasts on the substrate.

  1999cited by this paper
• Keratocytes generate traction forces in two phases.

  1999cited by this paper
• Cell migration: regulation of force on extracellular-matrix-integrin complexes.

  1998cited by this paper
• Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

  1997influential reference
• Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages.

  1997cited by this paper
• Traction forces of cytokinesis measured with optically modified elastic substrata

  1997cited by this paper
• Théorie de l"élasticité

  1990cited by this paper
• Experimental metastatic ability of H-ras-transformed NIH3T3 cells.

  1985cited by this paper
• Silicone rubber substrata: a new wrinkle in the study of cell locomotion.

  1980cited by this paper
• Contrôle optimal de systèmes gouvernés par des équations aux dérivées partielles

  1968cited by this paper
• between Integrin and the ECM in Focal Adhesions under Myosin II Tension

  year unknowncited by this paper

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  2025cites this paper
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  2025cites this paper
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  2022cites this paper
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  2022influential citation
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  2022cites this paper
• Efficient deformation mechanisms enable invasive cancer cells to migrate faster in 3D collagen networks

  2022cites this paper
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  2022influential citation
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  2021cites this paper
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