Differential Outcome of Tolerance Induction in Naive versus Activated Theiler's Virus Epitope-Specific CD8+ Cytotoxic T Cells

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Virology

• Publication date

  2007-04-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.00008-07PMID 17428853PMCID PMC1900084
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Multiple Sclerosis

  2007cited by this paper
• Interferon γ: a crucial role in the function of induced regulatory T cells in vivo

  2006cited by this paper
• Interferon gamma: a crucial role in the function of induced regulatory T cells in vivo.

  2006cited by this paper
• Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology.

  2006influential reference
• Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis.

  2005cited by this paper
• Antigen-Specific CD8+ T Cells Mediate a Peptide-Induced Fatal Syndrome1

  2005cited by this paper
• Cytotoxic T lymphocytes and autoimmunity

  2005cited by this paper
• Immunology of multiple sclerosis.

  2005cited by this paper
• Antibody response is required for protection from Theiler's virus-induced encephalitis in C57BL/6 mice in the absence of CD8+ T cells.

  2005cited by this paper
• Increased CD8+ Cytotoxic T Cell Responses to Myelin Basic Protein in Multiple Sclerosis1

  2004cited by this paper
• Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide

  2003cited by this paper
• Disease-modifying therapies in multiple sclerosis: an update on recent and ongoing trials and future strategies

  2003cited by this paper
• Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes

  2003cited by this paper
• Profound increase in sensitivity to glutamatergic‐ but not cholinergic agonist‐induced seizures in transgenic mice with astrocyte production of IL‐6

  2003cited by this paper
• Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

  2002cited by this paper
• Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

  2002cited by this paper
• Capsid-Specific Cytotoxic T Lymphocytes Recognize Three Distinct H-2Db-Restricted Regions of the BeAn Strain of Theiler's Virus and Exhibit Different Cytokine Profiles

  2002cited by this paper
• Multiple sclerosis.

  2002cited by this paper
• De Novo Central Nervous System Processing of Myelin Antigen Is Required for the Initiation of Experimental Autoimmune Encephalomyelitis1

  2002cited by this paper
• Theiler's virus infection of the mouse, or: of the importance of studying animal models.

  2002cited by this paper
• Enhanced susceptibility to Theiler's virus-induced demyelinating disease in perforin-deficient mice.

  2001cited by this paper
• Roles of the H-2D(b) and H-K(b) genes in resistance to persistent Theiler's murine encephalomyelitis virus infection of the central nervous system.

  2001cited by this paper
• Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial

  2000cited by this paper
• Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

  2000cited by this paper
• Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial. The Altered Peptide Ligand in Relapsing MS Study Group.

  2000cited by this paper
• Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

  2000cited by this paper
• H-2Db−/− Mice Are Susceptible to Persistent Infection by Theiler's Virus

  2000cited by this paper
• Shaping the repertoire of cytotoxic T-lymphocyte responses: explanation for the immunodominance effect whereby cytotoxic T lymphocytes specific for immunodominant antigens prevent recognition of nondominant antigens.

  1999cited by this paper
• Genetics of susceptibility to Theiler's virus infection

  1998cited by this paper
• On the mechanisms of immunodominance in cytotoxic T lymphocyte responses to minor histocompatibility antigens

  1997cited by this paper
• Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha.

  1995cited by this paper
• Mutation of a major histocompatibility class I locus, H-2D, leads to an increased virus burden and disease susceptibility in Theiler's virus-induced demyelinating disease.

  1995cited by this paper
• Theiler's virus infection of beta 2-microglobulin-deficient mice

  1993cited by this paper
• Class I‐deficient resistant mice intracerebrally inoculated with Theiler's virus show an increased T cell response to viral antigens and susceptibility to demyelination

  1993cited by this paper
• Abrogation of resistance to Theiler's virus-induced demyelination in H-2b mice deficient in beta 2-microglobulin.

  1993cited by this paper
• Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

  1993cited by this paper
• Theiler's VirusInfection ofP2-Microglobulin -Deficient Mice

  1993cited by this paper
• Cytokine‐related syndrome following injection of anti‐CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation

  1990cited by this paper
• Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides.

  1990cited by this paper
• Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction.

  1990cited by this paper
• Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells.

  1989cited by this paper
• Susceptibility to Theiler's virus-induced demyelination. Mapping of the gene within the H-2D region

  1986influential reference
• Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity.

  1985cited by this paper
• Demyelination induced by Theiler's virus: influence of the H-2 haplotype.

  1985influential reference
• [Immunology of multiple sclerosis].

  1982cited by this paper
• The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells

  1979cited by this paper
• Roles of the H-2 Db and HKb genes in resistance to persistent Theiler ’ s murine encephalomyelitis virus infection of the central nervous system

  year unknowncited by this paper

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  2021cites this paper
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  2019cites this paper
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  2018cites this paper
• Induced pluripotent stem cell technology: A window for studying the pathogenesis of acquired aplastic anemia and possible applications.

  2017cites this paper
• Virus infection, antiviral immunity, and autoimmunity

  2013cites this paper
• This information is current as Tolerance Induction Exploiting Apoptosis for Therapeutic

  2013cites this paper
• Exploiting Apoptosis for Therapeutic Tolerance Induction

  2013cites this paper
• Targeting the B7 Family of Co-Stimulatory Molecules

  2012cites this paper
• Virus expanded regulatory T cells control disease severity in the Theiler's virus mouse model of MS.

  2011cites this paper
• Current landscape for T-cell targeting in autoimmunity and transplantation.

  2011cites this paper
• A critical role for virus-specific CD8(+) CTLs in protection from Theiler's virus-induced demyelination in disease-susceptible SJL mice.

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2008cites this paper
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