Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Cancer Research

• Publication date

  2002-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12414623
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair*

  2002cited by this paper
• Functional analysis of MSH6 mutations linked to kindreds with putative hereditary non-polyposis colorectal cancer syndrome.

  2002cited by this paper
• Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer

  2002cited by this paper
• Molecular interactions of human Exo1 with DNA.

  2002cited by this paper
• The Interaction of DNA Mismatch Repair Proteins with Human Exonuclease I*

  2001cited by this paper
• Genome maintenance mechanisms for preventing cancer

  2001cited by this paper
• Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms.

  2001cited by this paper
• HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLα and hMLH1–hEXO1 complexes

  2001cited by this paper
• Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae.

  2001cited by this paper
• exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair

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• Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae

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• EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae.

  2000cited by this paper
• Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis.

  2000cited by this paper
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  1999cited by this paper
• The RAD2 Domain of Human Exonuclease 1 Exhibits 5′ to 3′ Exonuclease and Flap Structure-specific Endonuclease Activities*

  1999cited by this paper
• Human Exonuclease 1 Functionally Complements Its Yeast Homologues in DNA Recombination, RNA Primer Removal, and Mutation Avoidance*

  1999cited by this paper
• Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1

  1998cited by this paper
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  1998cited by this paper
• Partial Functional Deficiency of E160D Flap Endonuclease-1 Mutantin Vitro and in Vivo Is Due to Defective Cleavage of DNA Substrates*

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• Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy

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• Identification of novel biomarkers and small molecule drugs in human colorectal cancer by microarray and bioinformatics analysis

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• Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

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• An Integrated in Silico Approach to Analyze the Involvement of Single Amino Acid Polymorphisms in FANCD1/BRCA2-PALB2 and FANCD1/BRCA2-RAD51 Complex

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  2014influential citation
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  2013influential citation
• The mechanism of DNA double-strand break (DSB) resection in human cells

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