Keratin 8/18 Modulation of Protein Kinase C-mediated Integrin-dependent Adhesion and Migration of Liver Epithelial Cells

Hepatocyte and hepatoma cell IFs are made solely of keratins 8/18 (K8/K18). Cell adhesion and migration involve integrin interactions with focal adhesion kinase (FAK) and protein kinase C (PKC). Here we report a new regulatory function for K8/K18 IFs in the PKC-mediated integrin/FAK-dependent adhesion and migration of simple epithelial cells.

• Publication year

  2010

• Venue

  Molecular Biology of the Cell

• Publication date

  2010-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E09-05-0373PMID 20357007PMCID 2869376
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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