Metabolite Profiling: A Tool for the Biochemical Characterisation of Mycobacterium sp.

Over the last decades, the prevalence of drug-resistance in Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, has increased. These findings have rekindled interest in elucidating the unique adaptive molecular and biochemistry physiology of Mycobacterium. The use of metabolite profiling independently or in combination with other levels of “-omic” analyses has proven an effective approach to elucidate key physiological/biochemical mechanisms associated with Mtb throughout infection. The following review discusses the use of metabolite profiling in the study of tuberculosis, future approaches, and the technical and logistical limitations of the methodology.

• Publication year

  2019

• Venue

  Microorganisms

• Publication date

  2019-05-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.3390/microorganisms7050148PMID 31130621PMCID 6560386
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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