A Potential Role for Glucose Transporters in the Evolution of Human Brain Size

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Brain, Behavior and Evolution

• Publication date

  2011-10-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000329852PMID 21986508PMCID PMC3237107
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Pipeline to Determine RT-QPCR Control Genes for Evolutionary Studies: Application to Primate Gene Expression across Multiple Tissues

  2010cited by this paper
• Evolving gene expression: from G to E to GxE.

  2009cited by this paper
• The environmental contribution to gene expression profiles

  2008cited by this paper
• Regulation of Expression of the Region 3 Promoter of the Escherichia coli K5 Capsule Gene Cluster Involves H-NS, SlyA, and a Large 5′ Untranslated Region

  2008cited by this paper
• Patterns of Positive Selection in Six Mammalian Genomes

  2008cited by this paper
• A Genome-Wide Gene Expression Signature of Environmental Geography in Leukocytes of Moroccan Amazighs

  2008cited by this paper
• Human and Chimpanzee Gene Expression Differences Replicated in Mice Fed Different Diets

  2008cited by this paper
• Genetic basis of human brain evolution.

  2008cited by this paper
• Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution

  2008cited by this paper
• The selfish brain: Competition for energy resources

  2008cited by this paper
• Fibre type dependent expression of glucose transporters in human skeletal muscles.

  2007cited by this paper
• qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

  2007cited by this paper
• The GLUT4 glucose transporter.

  2007cited by this paper
• Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution

  2007influential reference
• Chimpanzee locomotor energetics and the origin of human bipedalism

  2007cited by this paper
• Effects of brain evolution on human nutrition and metabolism.

  2007cited by this paper
• GLUT1 deficiency syndrome – 2007 update

  2007cited by this paper
• 5′‐UTRs and Regulation

  2007cited by this paper
• Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony.

  2006cited by this paper
• Costs of encephalization: the energy trade-off hypothesis tested on birds.

  2006cited by this paper
• Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression.

  2006cited by this paper
• Conservation and evolution of gene coexpression networks in human and chimpanzee brains

  2006cited by this paper
• Evolution of the Size and Functional Areas of the Human Brain

  2006cited by this paper
• Response to Comment on "Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens" and "Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans"

  2006cited by this paper
• A mouse model for Glut-1 haploinsufficiency.

  2006cited by this paper
• A mouse model for Glut1 haploinsufficiency

  2006cited by this paper
• Evidence for Widespread Degradation of Gene Control Regions in Hominid Genomes

  2005cited by this paper
• Branching out

  2005cited by this paper
• A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees

  2005cited by this paper
• Dating of the human-ape splitting by a molecular clock of mitochondrial DNA

  2005cited by this paper
• Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS).

  2005cited by this paper
• USE OF GLUT‐4 NULL MICE TO STUDY SKELETAL MUSCLE GLUCOSE UPTAKE

  2005cited by this paper
• Microcephalin, a Gene Regulating Brain Size, Continues to Evolve Adaptively in Humans

  2005cited by this paper
• Evaluation of an improved branch-site likelihood method for detecting positive selection at the molecular level.

  2005cited by this paper
• Ongoing Adaptive Evolution of ASPM, a Brain Size Determinant in Homo sapiens

  2005cited by this paper
• Bayes empirical bayes inference of amino acid sites under positive selection.

  2005influential reference
• Detecting Selection in Noncoding Regions of Nucleotide Sequences

  2004cited by this paper
• The SLC2 family of facilitated hexose and polyol transporters

  2004cited by this paper
• The SLC2 family of facilitated hexose and polyol transporters

  2004cited by this paper
• Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles.

  2004cited by this paper
• The selfish brain: competition for energy resources.

  2004cited by this paper
• Metabolic correlates of hominid brain evolution.

  2003influential reference
• Elevated gene expression levels distinguish human from non-human primate brains

  2003cited by this paper
• Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins

  2003cited by this paper
• Intronic sequences flanking alternatively spliced exons are conserved between human and mouse.

  2003cited by this paper
• Peroxisome Proliferator-activated Receptor-γ Represses GLUT4 Promoter Activity in Primary Adipocytes, and Rosiglitazone Alleviates This Effect*

  2003cited by this paper
• Inferring Nonneutral Evolution from Human-Chimp-Mouse Orthologous Gene Trios

  2003cited by this paper
• Age-related changes in cerebral blood flow and glucose metabolism in conscious rhesus monkeys.

  2002cited by this paper
• Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

  2002cited by this paper
• dbSNP: the NCBI database of genetic variation

  2001cited by this paper
• Autosomal dominant Glut‐1 deficiency syndrome and familial epilepsy

  2001cited by this paper
• A new mathematical model for relative quantification in real-time RT-PCR.

  2001cited by this paper
• Glucose transporter expression in human skeletal muscle fibers.

  2000cited by this paper
• Direct evidence of fiber type-dependent GLUT-4 expression in human skeletal muscle.

  2000cited by this paper
• Three-dimensional stereotactic surface projection analysis of macaque brain PET: development and initial applications.

  2000cited by this paper
• Comparison of regional cerebral blood flow and glucose metabolism in the normal brain: effect of aging.

  2000cited by this paper
• Primer3 on the WWW for general users and for biologist programmers.

  2000cited by this paper
• Mutational analysis of GLUT1 (SLC2A1) in Glut‐1 Deficiency Syndrome

  2000cited by this paper
• Amplification of gene expression using both 5'- and 3'-untranslated regions of GLUT1 glucose transporter mRNA.

  1999cited by this paper
• Motor correlates of occipital glucose hypometabolism in Parkinson’s disease without dementia

  1999cited by this paper
• Metabolic and therapeutic lessons from genetic manipulation of GLUT4

  1998cited by this paper
• Neighboring-nucleotide effects on the rates of germ-line single-base-pair substitution in human genes.

  1998cited by this paper
• GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes

  1997cited by this paper
• The Expensive-Tissue Hypothesis: The Brain and the Digestive System in Human and Primate Evolution

  1995influential reference
• Glucose transporter proteins in brain

  1994cited by this paper
• Defective glucose transport across the blood-brain barrier as a cause of persistent hypoglycorrhachia, seizures, and developmental delay.

  1991cited by this paper
• Brain Size and Its Relation to the Rate of Metabolism in Mammals

  1989cited by this paper
• Body Composition and Energy Needs during Growth

  1978cited by this paper
• THE GENERAL METABOLISM OF THE BRAIN IN VIVO

  1957cited by this paper
• Open Access Research Article Evolutionary Ancestry and Novel Functions of the Mammalian Glucose Transporter (glut) Family

  year unknowncited by this paper
• Mutational Analysis of GLUT 1 ( SLC 2 A 1 ) in Glut1 Deficiency Syndrome

  year unknowncited by this paper
• BIOINFORMATICS APPLICATIONS

  year unknowncited by this paper

• Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment.

  2026cites this paper
• Micronutrients and the evolution of the human brain

  2023cites this paper
• Is obesity the next step in evolution through brain changes?

  2023cites this paper
• Extensive Non-Coding Sequence Divergence Between the Major Human Pathogen Aspergillus fumigatus and its Relatives

  2022influential citation
• Food made us human: Recent genetic variability and its relevance to the current distribution of macronutrients.

  2022cites this paper
• Extensive sequence divergence of non-coding regions between Aspergillus fumigatus, a major fungal pathogen of humans, and its relatives

  2021influential citation
• The Selfish Immune System when the Immune System Overrides the ‘Selfish’ Brain

  2020cites this paper
• A bigger brain for a more complex environment

  2020cites this paper
• Genetics of human brain evolution.

  2019cites this paper
• Life history changes accompany increased numbers of cortical neurons: A new framework for understanding human brain evolution.

  2019cites this paper
• Behavioral Economics, Evolution, and the Human Brain

  2018cites this paper
• A molecularly-imprinted-electrochemical-sensor modified with nano-carbon-dots with high sensitivity and selectivity for rapid determination of glucose.

  2018cites this paper
• Inflammation: a highly conserved, Janus-like phenomenon—a gastroenterologist’ perspective

  2018cites this paper
• Pathogenesis of Inflammatory Bowel Disease: Basic Science in the Light of Real-World Epidemiology

  2018cites this paper
• Paragraph 2.1. Physical Activity Protects the Human Brain against Metabolic Stress Induced by a Postprandial and Chronic Inflammation. Pruimboom

  2017cites this paper
• Energetic evolution of cellular Transportomes

  2017cites this paper
• Holocarboxylase Synthetase: A Moonlighting Transcriptional Coregulator of Gene Expression and a Cytosolic Regulator of Biotin Utilization.

  2017cites this paper
• Human Brain Expansion during Evolution Is Independent of Fire Control and Cooking

  2016cites this paper
• Physical Activity Protects the Human Brain against Metabolic Stress Induced by a Postprandial and Chronic Inflammation

  2015cites this paper
• Unraveling the Tangled Skein: The Evolution of Transcriptional Regulatory Networks in Development.

  2015cites this paper
• Neurodevelopmental LincRNA Microsyteny Conservation and Mammalian Brain Size Evolution

  2015cites this paper
• Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmission.

  2015influential citation
• Der Weg zum Homo sapiens

  2015cites this paper
• Genetically engineered mouse models of breast carcinoma: a translational resource for highlighting human breast subtype etiology and developing personalized therapeutic approaches

  2015cites this paper
• Genetic comparisons yield insight into the evolution of enamel thickness during human evolution.

  2014cites this paper
• The appropriation of glucose through primate neurodevelopment.

  2014cites this paper
• Transcriptomic insights into human brain evolution: acceleration, neutrality, heterochrony.

  2014cites this paper
• Gene Evolution and Human Adaptation

  2013cites this paper
• Rates of Evolution of Hominoid Seminal Proteins are Correlated with Function and Expression, Rather than Mating System

  2013cites this paper
• Evolution of genetic and genomic features unique to the human lineage

  2012cites this paper
• Metabolic constraint imposes tradeoff between body size and number of brain neurons in human evolution

  2012cites this paper