Trace: Tennessee Research and Creative Exchange Microbiology Publications and Other Works Microbiology Cutting Edge: Persistent Viral Infection Prevents Tolerance Induction and Escapes Immune Control following Cd28/cd40 Blockade-based Regimen Recommended Citation

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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation.

  1995cited by this paper
• Differential T cell costimulatory requirements in CD28-deficient mice.

  1993cited by this paper
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  1984cited by this paper

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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
• Micromanaging alloimmunity.

  2016cites this paper
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  2015cites this paper
• Detection of Virus-Specific CD8+ T Cells With Cross-Reactivity Against Alloantigens: Potency and Flaws of Present Experimental Methods

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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
• T-cell activation and transplantation tolerance.

  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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  2011cites this paper
• Limiting the Amount and Duration of Antigen Exposure during Priming Increases Memory T Cell Requirement for Costimulation during Recall

  2011cites this paper
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  2011cites this paper
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  2011influential citation
• Dendritic cells as a tool to induce transplantation tolerance: obstacles and opportunities.

  2011cites this paper
• Cross-immune tolerance: conception and its potential significance on transplantation tolerance

  2010cites this paper
• Innate Pathways of Immune Activation in Transplantation

  2010cites this paper
• Mechanism of cellular rejection in transplantation

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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  2004influential citation
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  2004cites this paper
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