Kinetics of GATA‐3 gene expression in early polarizing and committed human T cells

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Immunology

• Publication date

  2001-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1365-2567.2001.01168.xPMID 11260316PMCID PMC1783167
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• T Helper Type 2 Cell Differentiation Occurs in the Presence of Interleukin 12 Receptor β2 Chain Expression and Signaling

  2000cited by this paper
• Gata-3 Induces T Helper Cell Type 2 (Th2) Cytokine Expression and Chromatin Remodeling in Committed Th1 Cells

  2000cited by this paper
• Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.

  2000cited by this paper
• Upregulation of the transcription factor GATA-3 in upper airway mucosa after in vivo and in vitro allergen challenge.

  2000cited by this paper
• GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels.

  1999cited by this paper
• Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3.

  1999cited by this paper
• Gene expression of the GATA-3 transcription factor is increased in atopic asthma.

  1999cited by this paper
• Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation.

  1999cited by this paper
• The IL-4 receptor: signaling mechanisms and biologic functions.

  1999cited by this paper
• Transcriptional regulation of T lymphocyte development and function.

  1999cited by this paper
• GATA-3-dependent enhancer activity in IL-4 gene regulation.

  1998cited by this paper
• The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation.

  1998cited by this paper
• Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism.

  1998cited by this paper
• Cytokines induce the development of functionally heterogeneous T helper cell subsets.

  1998cited by this paper
• T lymphocyte differentiation in the periphery.

  1998cited by this paper
• Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3.

  1998cited by this paper
• Characterization of cis-regulatory elements and nuclear factors conferring Th2-specific expression of the IL-5 gene: a role for a GATA-binding protein.

  1998cited by this paper
• The Th1/Th2 paradigm.

  1997cited by this paper
• Th1 and Th2 CD4+ Cells in the Pathogenesis of Allergic Diseases

  1997cited by this paper
• Selective Expression of an Interleukin-12 Receptor Component by Human T Helper 1 Cells

  1997cited by this paper
• Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype.

  1997cited by this paper
• Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches.

  1997cited by this paper
• The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells.

  1997cited by this paper
• Cryo-electron microscopy reveals ordered domains in the immature HIV-1 particle.

  1997cited by this paper
• Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene*

  1997cited by this paper
• T-cell subsets: transcriptional control in the Th1/Th2 decision.

  1997cited by this paper
• Transcription factor GATA-3 is required for development of the T-cell lineage

  1996cited by this paper
• Functional diversity of helper T lymphocytes

  1996cited by this paper
• Reversibility of T helper 1 and 2 populations is lost after long-term stimulation

  1996cited by this paper
• Th1 and Th2 in human diseases.

  1996cited by this paper
• T-cell subsets. Who does the polarizing?

  1995cited by this paper
• T-Cell Subsets: Who does the polarizing?

  1995cited by this paper
• Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.

  1995cited by this paper
• Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

  1995cited by this paper
• Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

  1995cited by this paper
• Developmental commitment to the Th2 lineage by extinction of IL-12 signaling.

  1995cited by this paper
• GATA transcription factors: key regulators of hematopoiesis.

  1995cited by this paper
• Acquisition of lymphokine-producing phenotype by CD4+ T cells.

  1994cited by this paper
• Acquisition of lymphokine-producing phenotype by CD4+ T cells.

  1994cited by this paper
• Role of T Cells and T‐Cell‐Derived Cytokines in the Pathogenesis of Allergic Diseases

  1994cited by this paper
• Lymphocyte responses and cytokines.

  1994cited by this paper
• Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles

  1994cited by this paper
• Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages.

  1993cited by this paper
• Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequences

  1993cited by this paper
• DNA-binding specificity of GATA family transcription factors

  1993cited by this paper
• Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells.

  1993cited by this paper
• Transcriptional regulation of T cell receptor genes.

  1993cited by this paper
• Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent

  1993cited by this paper
• Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

  1993cited by this paper
• Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent.

  1993cited by this paper
• Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma.

  1992cited by this paper
• Human GATA‐3: a lineage‐restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

  1991cited by this paper
• Myeloma based expression system for production of large mammalian proteins.

  1991cited by this paper
• Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer

  1991cited by this paper
• IL-4 directs the development of Th2-like helper effectors.

  1990cited by this paper
• TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.

  1989cited by this paper
• Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

  1986cited by this paper
• Antigen-specific interaction between T and B cells

  1985cited by this paper

• Th cell transcription factors: Sequence characteristics and expression profiles in Epinephelus coioides after Cryptocaryon irritans infection

  2022cites this paper
• Human immunology and immunotherapy: main achievements and challenges

  2020cites this paper
• Taxifolin attenuates IMQ-induced murine psoriasis-like dermatitis by regulating T helper cell responses via Notch1 and JAK2/STAT3 signal pathways.

  2019cites this paper
• Ustekinumab treats psoriasis by suppressing RORC and T-box but its suppression of GATA restrains its efficacy

  2018cites this paper
• Exposure of Human CD8+ T Cells to Type-2 Cytokines Impairs Division and Differentiation and Induces Limited Polarization

  2018cites this paper
• The Single-Cell Phenotypic Identity of Human CD8+ and CD4+ T Cells.

  2018cites this paper
• Lipocalin‐2 is expressed by activated granulocytes and keratinocytes in affected skin and reflects disease activity in acne inversa/hidradenitis suppurativa

  2017cites this paper
• Integrative analyses reveal biological pathways and key genes in psoriasis

  2017cites this paper
• What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast

  2016cites this paper
• Trichloroethylene-induced hypersensitivity dermatitis was associated with hepatic metabolic enzyme genes and immune-related genes.

  2016cites this paper
• Investigating the immunoregulatory role of betaglycan

  2016cites this paper
• PAMPering immune responses : spotlight on helper cells for dendritic cell vaccination

  2015cites this paper
• T cell immune responses in psoriasis.

  2014cites this paper
• Effects of Th1 and Th2 cells balance in pulmonary injury induced by nano titanium dioxide.

  2014cites this paper
• Early Time-Dependent Dynamic Changes of TBET and GATA3 mRNA Expressions in Patients with Acute Coronary Syndrome

  2013cites this paper
• The CD4-centered universe of human T cell subsets.

  2013cites this paper
• Circulating leukocyte TBET and GATA3 mRNA in patients with acute coronary syndrome.

  2012cites this paper
• Profound tumor-specific Th2 bias in patients with malignant glioma

  2012cites this paper
• Immune regulation and modulation of allergy and inflammatory diseases

  2012cites this paper
• Suppressing GATA3 Th2 Commitment and Stability by Cutting Edge: Type I IFN Reverses Human

  2010cites this paper
• Expression of Th1 and Th2 cytokine-associated transcription factors, T-bet and GATA-3, in peripheral blood mononuclear cells and skin lesions of patients with psoriasis vulgaris

  2010cites this paper
• Current and emerging strategies for the treatment and management of systemic lupus erythematosus based on molecular signatures of acute and chronic inflammation

  2010cites this paper
• Cutting Edge: Type I IFN Reverses Human Th2 Commitment and Stability by Suppressing GATA3

  2010cites this paper
• Human Invariant NKT Cells Driven by IL-7 Innate-Like Effector Differentiation of Casorati Aiuti

  2008cites this paper
• Innate-Like Effector Differentiation of Human Invariant NKT Cells Driven by IL-71

  2008cites this paper
• Inflammatory immune reactivity to cereal proteins in type 1 diabetes

  2007cites this paper
• Expression of T-bet, a type 1 T-helper cell transcription factor, in the urinary sediment of lupus patients predicts disease flare.

  2007cites this paper
• REGULATORY MECHANISMS INVOLVED IN TH2 CELL DIFFERENTIATION

  2007cites this paper
• Th1, Th2 and Treg associated factors in relation to allergy

  2006cites this paper
• Imbalance of Th1/Th2 transcription factors in patients with lupus nephritis.

  2006cites this paper
• T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

  2006cites this paper
• Imbalance of Th 1 / Th 2 transcription factors in patients with lupus nephritis

  2006cites this paper
• IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells.

  2005cites this paper
• CXCR3-mediated opposite effects of CXCL10 and CXCL4 on TH1 or TH2 cytokine production.

  2005cites this paper
• IL‐12 up‐regulates T‐bet independently of IFN‐γ in human CD4+ T cells

  2005cites this paper
• Expression Factor for Regulating Human NKG 2 A Gene GATA-3 Is an Important Transcription Borrego and

  2005cites this paper
• GATA-3 Is an Important Transcription Factor for Regulating Human NKG2A Gene Expression

  2005cites this paper
• Graft-vs.-Host Disease as a Th1-Type Process: Regulation by Th2-Type Cells

  2004cites this paper
• Advances in the clinical laboratory assessment of urinary sediment.

  2004cites this paper
• Th1 and Th2 cytokine production is suppressed at the level of transcriptional regulation in Kawasaki disease

  2004cites this paper
• Differential Regulation of Th1/Th2 Cytokine Responses by Placental Protein 141

  2004cites this paper
• T-bet/GATA-3 ratio as a measure of the Th1/Th2 cytokine profile in mixed cell populations: predominant role of GATA-3.

  2003cites this paper
• Dexamethasone inhibits the binding of nuclear factors to the IL-5 promoter in human CD4 T cells.

  2001cites this paper
• The Journal of Experimental Medicine

  2000cites this paper