Molecular neurobiological clues to the pathogenesis of bipolar disorder

Highlights • Bipolar disorder has a large genetic component, with many loci involved.• Leading genes include CACNA1C and ANK3.• There is genetic convergence on calcium signalling and other pathways.• Genetic mouse models, and stem cells, are shedding light on pathogenesis.• The advances have potential therapeutic benefits, but these remain distant.

• Publication year

  2016

• Venue

  Current Opinion in Neurobiology

• Publication date

  2016-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.conb.2015.07.002PMID 26210959PMCID 4779149
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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