Protein kinase C activity and multidrug resistance in MOLT-3 human lymphoblastic leukemia cells resistant to trimetrexate.

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Cancer Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 1824824
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Multidrug resistance in human cancer.

  1992cited by this paper
• Multidrug resistance in a human leukemic cell line selected for resistance to trimetrexate.

  1989cited by this paper
• Protein kinase C in adriamycin action and resistance in mouse sarcoma 180 cells.

  1989cited by this paper
• The protein kinase C family: heterogeneity and its implications.

  1989cited by this paper
• Multidrug resistance.

  1988cited by this paper
• The molecular heterogeneity of protein kinase C and its implications for cellular regulation

  1988cited by this paper
• Role of protein kinase C in phosphorylation of vinculin in adriamycin-resistant HL-60 leukemia cells.

  1988cited by this paper
• Phorbol esters induce multidrug resistance in human breast cancer cells.

  1988cited by this paper
• Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action.

  1988cited by this paper
• Phosphorylation of the Mr 170,000 to 180,000 glycoprotein specific to multidrug-resistant tumor cells: effects of verapamil, trifluoperazine, and phorbol esters.

  1987cited by this paper
• Decreased phorbol ester receptor and protein kinase C in P388 murine leukemic cells resistant to etoposide.

  1987cited by this paper
• Effects of phorbol ester on translocation and down-regulation of protein kinase C and phosphorylation of endogenous proteins in human acute myeloid leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.

  1987cited by this paper
• Enhancement of voltage-gated Na+ channel current associated with multidrug resistance in human leukemia cells.

  1987cited by this paper
• Transient protection of cultured human cells against antitumor agents by 12-O-tetradecanoylphorbol-13-acetate.

  1987cited by this paper
• Time-dependent changes in protein kinase C distribution and disappearance in phorbol ester-treated human osteosarcoma cells.

  1987cited by this paper
• TPA induces subcellular translocation and subsequent down-regulation of both phorbol ester binding and protein kinase C activities in MCF-7 cells.

  1987cited by this paper
• Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60.

  1987cited by this paper
• Multiple-drug resistance in human cancer.

  1987cited by this paper
• Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats.

  1986cited by this paper
• Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine.

  1986cited by this paper
• Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase.

  1986cited by this paper
• Calcium, calmodulin, and protein content of adriamycin-resistant and -sensitive murine leukemic cells.

  1986cited by this paper
• Evolution of methotrexate resistance of human acute lymphoblastic leukemia cells in vitro.

  1985cited by this paper
• Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C.

  1984cited by this paper
• Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

  1983cited by this paper
• Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines.

  1983cited by this paper
• Enhancement of sensitivity to adriamycin in resistant P388 leukemia by the calmodulin inhibitor trifluoperazine.

  1983cited by this paper
• Phorbol diester receptor copurifies with protein kinase C.

  1983cited by this paper
• Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

  1982cited by this paper
• Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

  1982cited by this paper
• Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

  1981cited by this paper
• Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.

  1980cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes.

  1972cited by this paper

• Effect of Phorbol 12-Myristate 13-Acetate on Function and Gene Expression of P-Glycoprotein in Adriamycin-Resistant K562/ADM Cells

  2013cites this paper
• PKC and Resistance to Chemotherapeutic Agents

  2010cites this paper
• Natural Agents That Can Sensitize Tumor Cells to Chemotherapy and Radiation Therapy

  2008cites this paper
• Leukemia Cell Line HL-60 Daunomycin with Sphinganine on the Differentiation of Human Interaction of Antileukemia Agents Adriamycin and Updated Version

  2006cites this paper
• From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

  2006cites this paper
• Inhibition of protein kinase C in multidrug-resistant cells by modulators of multidrug resistance

  2005cites this paper
• From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

  2005cites this paper
• Differential Effects of Dietary Fatty Acids on the Regulation of CYP2E1 and Protein Kinase C in Human Hepatoma HepG2 Cells

  2004cites this paper
• Modulation of protein kinase C in antitumor treatment.

  2001cites this paper
• Mechanisms of action of flavopiridol.

  2001cites this paper
• Protein Kinase C Isoform Expression and Activity Alter Paclitaxel Resistancein Vitro

  1999cites this paper
• Protein kinase C isoform expression and activity alter paclitaxel resistance in vitro.

  1999cites this paper
• Estrogenic xenobiotics affect the intracellular activation signal in mitogen-induced human peripheral blood lymphocytes: immunotoxicological impact.

  1998cites this paper
• Neurosurgery 1992-98 March 1995, Volume 36, Number 3 565 Effects of Protein Kinase C Modulators on Multidrug Resistance in Human Glioma Cells

  1998cites this paper
• Protein kinases and multidrug resistance

  1998cites this paper
• Sex hormones affect the intracellular activation signal in mitogen-stimulated human blood lymphocytes

  1998cites this paper
• Corosolic acid isolated from the fruit of Crataegus pinnatifida var. psilosa is a protein kinase C inhibitor as well as a cytotoxic agent.

  1998cites this paper
• Increase of nuclear phosphatidylinositol 4,5‐bisphosphate and phospholipase C β1 is not associated to variations of protein kinase C in multidrug‐resistant Saos‐2 cells

  1997cites this paper
• Expression, subcellular distribution and response to phorbol esters of protein kinase C (PKC) isozymes in drug-sensitive and multidrug-resistant KB cells evidence for altered regulation of PKC-alpha.

  1996cites this paper
• P-Glycoprotein, Multidrug Resistance and Protein Kinase C.

  1996cites this paper
• P‐Glycoprotein, Multidrug Resistance and Protein Kinase C

  1996cites this paper
• Effects of protein kinase C modulators on multidrug resistance in human glioma cells.

  1995cites this paper
• Evaluation of 2,6-Diamino-N-([1-(1-oxotridecyl)-2-piperidinyl]methyl) hexanamide (NPC 15437), a protein kinase C inhibitor, as a modulator of P-glycoprotein-mediated resistancein vitro

  1995cites this paper
• The role of protein kinase C in multidrug resistance.

  1994cites this paper
• Regulation of protein kinase C and role in cancer biology

  1994cites this paper
• Prognostic-significance of protein-kinase-C in newly-diagnosed childhood acute lymphoblastic-leukemia.

  1994cites this paper
• Induction of resistance to daunorubicin in drug-sensitive leukemia p388 cells - a role of pkc-Beta-I isozyme.

  1994cites this paper
• Comparative study of intracellular calcium and adenosine 3',5'-cyclic monophosphate levels in human breast carcinoma cells sensitive or resistant to Adriamycin: contribution to reversion of chemoresistance.

  1994cites this paper
• Effect of Calphostin C (PKC inhibitor) on daunorubicin resistance in P388/ADR and HL60/AR cells: reversal of drug resistance possibly via P-glycoprotein.

  1994cites this paper
• Phorbol 12-myristate 13-acetate (pma) induces neuroendocrine-like differentiation and reverses Doxorubicin-resistance of human colon-carcinoma cells in-vitro.

  1994cites this paper
• Human leukemia K562 cell mutant (K562/OA200) selected for resistance to okadaic acid (protein phosphatase inhibitor) lacks protein kinase C-epsilon, exhibits multidrug resistance phenotype, and expresses drug pump P-glycoprotein.

  1994cites this paper
• Expression of protein-kinase-C isozymes in multidrug-resistant murine leukemia p388/adr cells.

  1994cites this paper
• Effect of tamoxifen on the multidrug-resistant phenotype in human breast cancer cells: isobologram, drug accumulation, and M(r) 170,000 glycoprotein (gp170) binding studies.

  1994cites this paper
• GTP-stimulated phosphorylation of P-glycoprotein in transporting vesicles from KB-V1 multidrug resistant cells.

  1994cites this paper
• Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha.

  1993cites this paper
• The potential of protein kinase C as a target for anticancer treatment.

  1993cites this paper
• Multidrug resistance mediated by P-glycoprotein in haematological malignancies.

  1993cites this paper
• Interaction of antileukemia agents adriamycin and daunomycin with sphinganine on the differentiation of human leukemia cell line HL-60.

  1992cites this paper
• Effects of adriamycin and daunomycin on ornithine decarboxylase activity and DNA synthesis in mouse epidermal cells.

  1992cites this paper
• An overview of membrane, cytosolic and nuclear proteins associated with the expression of resistance to multiple drugs in vitro.

  1992cites this paper
• Stable expression of a cDNA encoding rat brain protein kinase C-beta I confers a multidrug-resistant phenotype on rat fibroblasts.

  1992cites this paper
• The role of protein kinase C and the phosphatidylinositol cycle in multidrug resistance in human ovarian cancer cells.

  1991cites this paper