Rapid phosphotransfer to CheY from a CheA protein lacking the CheY-binding domain.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Biochemistry

• Publication date

  2000-10-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/BI001100KPMID 11052668
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• FEBS Lett

  2000cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1980cited by this paper
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  year unknowncited by this paper

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