Antibacterial efficacy of inhaled squalamine in a rat model of chronic Pseudomonas aeruginosa pneumonia.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Antimicrobial Chemotherapy

• Publication date

  2012-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/jac/dks230PMID 22744759
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A rat model of chronic respiratory infection with Pseudomonas aeruginosa.

  2015cited by this paper
• Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential

  2011cited by this paper
• Squalamine ointment for Staphylococcus aureus skin decolonization in a mouse model.

  2011cited by this paper
• Discovery research: the scientific challenge of finding new antibiotics.

  2011cited by this paper
• Suitability of a new antimicrobial aminosterol formulation for aerosol delivery in cystic fibrosis.

  2011cited by this paper
• Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution

  2011cited by this paper
• New treatment options against gram-negative organisms

  2011cited by this paper
• Nebulized ceftazidime and amikacin in ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

  2011cited by this paper
• Inhaled antibiotic therapy for ventilator-associated tracheobronchitis and ventilator-associated pneumonia: an Update

  2011cited by this paper
• New insights into the antibacterial mechanism of action of squalamine.

  2010cited by this paper
• Squalamine as an example of a new potent antimicrobial agents class: a critical review.

  2010cited by this paper
• Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa

  2010cited by this paper
• In vitro antifungal activity of aminosterols against moulds isolated from cystic fibrosis patients.

  2010cited by this paper
• In vitro antibacterial activity of aminosterols against multidrug-resistant bacteria from patients with cystic fibrosis.

  2009cited by this paper
• Intratracheal colistin sulfate for BALB/c mice with early pneumonia caused by carbapenem-resistant Acinetobacter baumannii

  2009cited by this paper
• Role of old antibiotics in multidrug resistant bacterial infections.

  2009cited by this paper
• Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections.

  2008cited by this paper
• Squalamine: An Appropriate Strategy against the Emergence of Multidrug Resistant Gram-Negative Bacteria?

  2008cited by this paper
• Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE.

  2008cited by this paper
• Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit*

  2008cited by this paper
• In Vivo Growth of Pseudomonas aeruginosa Strains PAO1 and PA14 and the Hypervirulent Strain LESB58 in a Rat Model of Chronic Lung Infection

  2007cited by this paper
• In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery.

  2006cited by this paper
• Toxicity of polymyxins: a systematic review of the evidence from old and recent studies

  2006cited by this paper
• Squalamine: a polyvalent drug of the future?

  2005cited by this paper
• Disposition of instilled versus nebulized tobramycin and imipenem in ventilated intensive care unit (ICU) patients.

  2004cited by this paper
• A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.

  2003cited by this paper
• Nebulized Antibiotics in Cystic Fibrosis

  2002cited by this paper
• Lung deposition and efficiency of nebulized amikacin during Escherichia coli pneumonia in ventilated piglets.

  2002cited by this paper
• Characterization of an animal model of ventilator-acquired pneumonia.

  1999cited by this paper
• Relationship of microbiologic diagnostic criteria to morbidity and mortality in patients with ventilator-associated pneumonia.

  1998cited by this paper
• Relationship of Microbiologic Diagnostic Criteria to Morbidity and Mortality in Patients With Ventilator-Associated Pneumonia

  1997cited by this paper
• Efficacy of prophylactic aerosol amphotericin B lipid complex in a rat model of pulmonary aspergillosis

  1997cited by this paper
• Aerosol amphotericin B is effective for prophylaxis and therapy in a rat model of pulmonary aspergillosis

  1988cited by this paper

• Animal Models of Pseudomonas aeruginosa Lung Infection

  2024cites this paper
• Antimicrobial, Cytotoxic and Phytochemical Analysis of Chloroform Extracts of Andrographis paniculata Root (Burm.F) and Parquetina nigrescens (Afzel) Aerial Part

  2024cites this paper
• Squalamine and Its Aminosterol Derivatives: Overview of Biological Effects and Mechanisms of Action of Compounds with Multiple Therapeutic Applications

  2022cites this paper
• From Marine Metabolites to the Drugs of the Future: Squalamine, Trodusquemine, Their Steroid and Triterpene Analogues

  2022cites this paper
• New Classes of Broad-Spectrum Antibiotics and New Mechanisms of Delivery

  2021cites this paper
• Azithromycin Exhibits Activity Against Pseudomonas aeruginosa in Chronic Rat Lung Infection Model

  2021cites this paper
• Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic.

  2021cites this paper
• Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening

  2021cites this paper
• Synthesis and Biological Activities of Natural Functionalized Polyamines: An Overview.

  2020cites this paper
• Ultraviolet Radiation From a Plant Perspective: The Plant-Microorganism Context

  2020cites this paper
• Characterization of Crude Extracts from Cassia alata Linn. against Cellulitis Causing Agent Staphylococcus aureus

  2019cites this paper
• The Biological Activity of Natural Alkaloids against Herbivores, Cancerous Cells and Pathogens

  2019cites this paper
• Interactions between Aspergillus fumigatus and Pulmonary Bacteria: Current State of the Field, New Data, and Future Perspective

  2019cites this paper
• Fibromyalgia Symptoms – A Review

  2018cites this paper
• Antimicrobial activity of newly synthesized thienoquinolizidines derivatives: inspired by natural plant alkaloids

  2017cites this paper
• Natural Products as Promising Pharmacological Tools for the Management of Fibromyalgia Symptoms – A Review

  2017cites this paper
• Animal Models to Evaluate Anti-infective Pharmacodynamics

  2016cites this paper
• Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents.

  2016cites this paper
• Bacteriophage-based therapy in cystic fibrosis-associated Pseudomonas aeruginosa infections: rationale and current status

  2015cites this paper
• Animal models of polymicrobial pneumonia

  2015cites this paper
• DRUGS FROM THE SEA: A REVIEW OF MARINE DRUGS IN THE PIPELINE AND THE CHALLENGES FACED BY RESEARCHERS IN MARINE DRUG DEVELOPMENT.

  2015cites this paper
• Anti-­Infective Agents from Marine Sources

  2015cites this paper
• Bactericidal Activities of Cathelicidin LL-37 and Select Cationic Lipids against the Hypervirulent Pseudomonas aeruginosa Strain LESB58

  2015cites this paper
• Bacteriophage-based therapy in cystic fibrosis-associated Pseudomonas aeruginosa infections: rationale and current status

  2015cites this paper
• Bacteriophage-based therapy in cystic fibrosis-associated Pseudomonas aeruginosa infections: rationale and current status

  2015cites this paper
• Pneumoniabaumannii in a Rat Model of Colistin-Resistant Clinical Isolate of Impaired Virulence and Fitness of a

  2014cites this paper
• Non-Genotoxic Assessment of a Natural Antimicrobial Agent: Squalamine

  2014cites this paper
• Evaluation de stratégies thérapeutiques dans des modèles murins de pneumonie

  2014cites this paper
• Inhaled Lactonase Reduces Pseudomonas aeruginosa Quorum Sensing and Mortality in Rat Pneumonia

  2014cites this paper
• Alkaloids: an overview of their antibacterial, antibiotic-enhancing and antivirulence activities.

  2014influential citation
• Promises of the Unprecedented Aminosterol Squalamine

  2014cites this paper
• A Lung Segmental Model of Chronic Pseudomonas Infection in Sheep

  2013cites this paper
• Clinical experimentation with aerosol antibiotics: current and future methods of administration

  2013cites this paper
• Impaired Virulence and Fitness of a Colistin-Resistant Clinical Isolate of Acinetobacter baumannii in a Rat Model of Pneumonia

  2013cites this paper
• In Silico Molecular Docking of Marine Drugs Against Cancer Proteins

  2013cites this paper
• New insights in the production of aerosol antibiotics. Evaluation of the optimal aerosol production system for ampicillin-sulbactam, meropenem, ceftazidime, cefepime and piperacillin-tazobactam.

  2013cites this paper
• Marine-Derived Angiogenesis Inhibitors for Cancer Therapy

  2013cites this paper