Regulation of parathyroid hormone-related protein gene expression by epidermal growth factor-family ligands in primary human keratinocytes.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Endocrinology

• Publication date

  2004-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1677/JOE.0.1810179PMID 15072578
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003influential reference
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  1998influential reference
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  1992influential reference
• Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes. Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion.

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  1989influential reference
• Parathyroid hormone‐related protein: Immunohistochemical localization in cancers and in normal skin

  1989influential reference
• Expression of transcripts encoding a parathyroid hormone-related peptide in abnormal human parathyroid tissues.

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• Humoral Hypercalcemia of Cancer

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  1988cited by this paper
• Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis.

  1986cited by this paper
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  1986cited by this paper
• Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups.

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