Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Neuroscience

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.NEUROSCIENCE.2006.02.067PMID 16600521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neuroscience

  2008cited by this paper
• The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines

  2007cited by this paper
• Conditioned locomotor activity but not conditioned place preference following intra-accumbens infusions of cocaine

  2005cited by this paper
• Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons.

  2005cited by this paper
• Dopamine Receptor Stimulation Modulates AMPA Receptor Synaptic Insertion in Prefrontal Cortex Neurons

  2005cited by this paper
• Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.

  2005cited by this paper
• Behavioral Sensitization to Cocaine Is Associated with Increased AMPA Receptor Surface Expression in the Nucleus Accumbens

  2005cited by this paper
• Effect of MS-153, a glutamate transporter activator, on the conditioned rewarding effects of morphine, methamphetamine and cocaine in mice.

  2005cited by this paper
• Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: Localization to and within dendritic spines

  2004cited by this paper
• Psychomotor stimulants and neuronal plasticity.

  2004cited by this paper
• The identification of a second actin-binding region in spinophilin/neurabin II.

  2004cited by this paper
• Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity.

  2004cited by this paper
• DARPP-32: an integrator of neurotransmission.

  2004cited by this paper
• Subcellular distribution of neurabin immunolabeling in primate prefrontal cortex: comparison with spinophilin.

  2004cited by this paper
• Therapeutic doses of L-dopa reverse hypersensitivity of corticostriatal D2-dopamine receptors and glutamatergic overactivity in experimental parkinsonism.

  2004cited by this paper
• D1 dopamine receptor stimulation increases the rate of AMPA receptor insertion onto the surface of cultured nucleus accumbens neurons through a pathway dependent on protein kinase A

  2004cited by this paper
• Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F‐actin in dendritic spines

  2004cited by this paper
• Homer proteins regulate sensitivity to cocaine.

  2004cited by this paper
• Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton.

  2004cited by this paper
• Potentiation of NMDA receptor currents by dopamine D1 receptors in prefrontal cortex.

  2004cited by this paper
• Learning mechanisms in addiction: synaptic plasticity in the ventral tegmental area as a result of exposure to drugs of abuse.

  2004cited by this paper
• It could be habit forming: drugs of abuse and striatal synaptic plasticity.

  2003cited by this paper
• Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists.

  2003cited by this paper
• Dopamine receptor-interacting proteins: the Ca(2+) connection in dopamine signaling.

  2003cited by this paper
• Receptor Subtypes Involved in the Presynaptic and Postsynaptic Actions of Dopamine on Striatal Interneurons

  2003cited by this paper
• Spinophilin Stabilizes Cell Surface Expression of α2B-Adrenergic Receptors*

  2003cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Phosphorylation of Spinophilin Modulates Its Interaction with Actin Filaments*

  2003cited by this paper
• Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors.

  2003cited by this paper
• RGS9 modulates dopamine signaling in the basal ganglia.

  2003cited by this paper
• Segregation of Amphetamine Reward and Locomotor Stimulation between Nucleus Accumbens Medial Shell and Core

  2003cited by this paper
• Distinct Roles of D1 and D5 Dopamine Receptors in Motor Activity and Striatal Synaptic Plasticity

  2003influential reference
• Regulated interactions of the alpha 2A adrenergic receptor with spinophilin, 14-3-3zeta, and arrestin 3.

  2002cited by this paper
• Regulated Interactions of the α2A Adrenergic Receptor with Spinophilin, 14-3-3ζ, and Arrestin 3*

  2002cited by this paper
• D1 dopamine receptor stimulation increases GluR1 surface expression in nucleus accumbens neurons

  2002cited by this paper
• The Mouse Brain in Stereotaxic Coordinates

  2001cited by this paper
• A cellular mechanism of reward-related learning

  2001cited by this paper
• Regulation of synaptic strength by protein phosphatase 1.

  2001cited by this paper
• Dopaminergic control of synaptic plasticity in the dorsal striatum

  2001cited by this paper
• Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin.

  2001cited by this paper
• Agonist-regulated Interaction between α2-Adrenergic Receptors and Spinophilin*

  2001cited by this paper
• Dopamine and cAMP-Regulated Phosphoprotein 32 kDa Controls Both Striatal Long-Term Depression and Long-Term Potentiation, Opposing Forms of Synaptic Plasticity

  2000cited by this paper
• Spinophilin regulates the formation and function of dendritic spines.

  2000cited by this paper
• Regulation of Phosphorylation of the GluR1 AMPA Receptor in the Neostriatum by Dopamine and Psychostimulants In Vivo

  2000cited by this paper
• Addiction, Dopamine, and the Review Molecular Mechanisms of Memory

  2000cited by this paper
• Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.

  1999cited by this paper
• Association of the D2 Dopamine Receptor Third Cytoplasmic Loop with Spinophilin, a Protein Phosphatase-1-interacting Protein*

  1999cited by this paper
• Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.

  1999cited by this paper
• Construction of gene targeting vectors from lambda KOS genomic libraries.

  1999cited by this paper
• Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP–32 and spinophilin

  1999cited by this paper
• Construction of Gene Targeting Vectors from λKOS Genomic Libraries

  1999cited by this paper
• A Dopamine/D1 Receptor/Protein Kinase A/Dopamine- and cAMP-Regulated Phosphoprotein (Mr 32 kDa)/Protein Phosphatase-1 Pathway Regulates Dephosphorylation of the NMDA Receptor

  1998cited by this paper
• NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus.

  1998cited by this paper
• Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression.

  1998cited by this paper
• Neurabin-II/Spinophilin

  1998cited by this paper
• Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas.

  1997cited by this paper
• Neurabin: A Novel Neural Tissue–specific Actin Filament–binding Protein Involved in Neurite Formation

  1997cited by this paper
• Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines.

  1997cited by this paper
• Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit.

  1996cited by this paper
• Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

  1994cited by this paper
• Isolation rearing enhances the locomotor response to cocaine and a novel environment, but impairs the intravenous self-administration of cocaine

  1994cited by this paper
• The basolateral amygdala-ventral striatal system and conditioned place preference: further evidence of limbic-striatal interactions underlying reward-related processes.

  1991cited by this paper
• Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

  1987cited by this paper
• Concluding Summary

  1976cited by this paper
• Behavioral/systems/cognitive Behavioral Sensitization to Cocaine Is Associated with Increased Ampa Receptor Surface Expression in the Nucleus Accumbens

  year unknowncited by this paper

• Proteomic Characterization of Striatal Neurabin Interactome and its Sex Specific Impact on Motor Behavior

  2025cites this paper
• Striatal spinophilin enhances dopamine D2 receptor (D2R) interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression.

  2025cites this paper
• Proximity labeling and orthogonal nanobody pulldown (ID-oPD) approaches to map the spinophilin interactome uncover a putative role for spinophilin in protein homeostasis

  2025cites this paper
• Striatal spinophilin enhances D2R interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression

  2025cites this paper
• Proximity interactome mapping furthers a role for spinophilin in protein homeostasis

  2025cites this paper
• Mechanisms of spinophilin-dependent pancreas dysregulation in obesity

  2024cites this paper
• Spinophilin‐dependent regulation of GluN2B‐containing NMDAR‐dependent calcium influx, GluN2B surface expression, and cleaved caspase expression

  2023cites this paper
• Mechanisms of spinophilin-dependent pancreas dysregulation underlying diabesity

  2023cites this paper
• SIPA1L1/SPAR1 Interacts with the Neurabin Family of Proteins and is Involved in GPCR Signaling

  2022cites this paper
• A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer’s model

  2022cites this paper
• Spinophilin limits metabotropic glutamate receptor 5 scaffolding to the postsynaptic density and cell type-specifically mediates excessive grooming

  2022cites this paper
• The phospho-landscape of the survival of motoneuron protein (SMN) protein: relevance for spinal muscular atrophy (SMA)

  2022cites this paper
• Spinophilin limits GluN2B-containing NMDAR activity and sequelae associated with excessive hippocampal NMDAR function

  2021cites this paper
• Modulation of dendritic spines by protein phosphatase-1.

  2021influential citation
• Modulated Start-Up Mode of Cancer Cell Migration Through Spinophilin-Tubular Networks

  2021cites this paper
• Role of the Holoenzyme PP1-SPN in the Dephosphorylation of the RB Family of Tumor Suppressors During Cell Cycle

  2021cites this paper
• SIPA1L1/SPAR1 is a non-PSD protein involved in GPCR signaling

  2021cites this paper
• Palmitoylated prolactin-releasing peptide reduced Aβ plaques and microgliosis in the cerebellum: APP/PS1 mice study.

  2021cites this paper
• Regulation of Synaptic Transmission and Plasticity by Protein Phosphatase 1

  2021cites this paper
• Spinophilin-deficient Mice are Protected from Diet-induced Obesity and Insulin Resistance.

  2020cites this paper
• Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation

  2019cites this paper
• Spinophilin regulates phosphorylation and interactions of the GluN2B subunit of the N‐methyl‐d‐aspartate receptor

  2019cites this paper
• cAMP regulation of protein phosphatases PP1 and PP2A in brain.

  2019cites this paper
• Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

  2018cites this paper
• Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics

  2018cites this paper
• Mechanisms Regulating the Association of Protein Phosphatase 1 with Spinophilin and Neurabin.

  2018cites this paper
• The association of spinophilin with disks large‐associated protein 3 (SAPAP3) is regulated by metabotropic glutamate receptor (mGluR) 5

  2018influential citation
• Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin / NeurofilamentMedium Interaction

  2017influential citation
• Altered learning, memory, and social behavior in type 1 taste receptor subunit 3 knock-out mice are associated with neuronal dysfunction

  2017cites this paper
• Age-dependent differential regulation of anxiety- and depression-related behaviors by neurabin and spinophilin

  2017cites this paper
• Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction

  2017cites this paper
• Regulation of Striatal Signaling by Protein Phosphatases

  2017cites this paper
• Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity*

  2016cites this paper
• Loss of the tumor suppressor spinophilin (PPP1R9B) increases the cancer stem cell population in breast tumors

  2016cites this paper
• PDZ Protein Regulation of G Protein–Coupled Receptor Trafficking and Signaling Pathways

  2015cites this paper
• Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.

  2015cites this paper
• Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

  2015cites this paper
• Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)

  2015cites this paper
• Spinophilin-Targeted Protein Phosphatase-1 Alleviated Inflammatory Pain by Negative Control of MEK/ERK Signaling in Spinal Cord Dorsal Horn of Rats

  2015cites this paper
• Dendritic spine morphology and dynamics in health and disease

  2015cites this paper
• Biological substrates of addiction.

  2014cites this paper
• What does genetics tell us about imprinting and the placenta connection?

  2014cites this paper
• The tumour suppressor function of the scaffolding protein spinophilin

  2014cites this paper
• Hippocampal Y2 receptor-mediated mossy fiber plasticity is implicated in nicotine abstinence-related social anxiety-like behavior in an outbred rat model of the novelty-seeking phenotype.

  2014cites this paper
• Phenotypic outcomes of imprinted gene models in mice: elucidation of pre- and postnatal functions of imprinted genes.

  2014cites this paper
• Neuroplasticity, axonal guidance and micro‐RNA genes are associated with morphine self‐administration behavior

  2013cites this paper
• Constitutive knockout of the membrane cytoskeleton protein beta adducin decreases mushroom spine density in the nucleus accumbens but does not prevent spine remodeling in response to cocaine

  2013cites this paper
• Low expression of the putative tumour suppressor spinophilin is associated with higher proliferative activity and poor prognosis in patients with hepatocellular carcinoma

  2013cites this paper
• Dopamine D1 sensitivity in the prefrontal cortex predicts general cognitive abilities and is modulated by working memory training

  2013cites this paper
• Differential association of postsynaptic signaling protein complexes in striatum and hippocampus

  2013cites this paper
• signaling dependent - SHP-1, modulates platelet activation by regulating G protein A newly identified complex of spinophilin and the tyrosine phosphatase,

  2013cites this paper
• The Synaptic Adhesion Molecule SynCAM 1 Contributes to Cocaine Effects on Synapse Structure and Psychostimulant Behavior

  2013cites this paper
• Characterization of the Rho-GEF Kalirin-7 in the Mouse Brain: Evidence for a Role in Learning and Addictive-Like Behaviors, as Well as Neuronal Morphology and NMDA Receptor Signaling.

  2013cites this paper
• Dopaminergic sensitivity in the prefrontal cortex is associated with variations in general cognitive abilities and is a target for working memory training

  2012cites this paper
• Neurabin Scaffolding of Adenosine Receptor and RGS4 Regulates Anti-Seizure Effect of Endogenous Adenosine

  2012cites this paper
• [When the curtain goes up on spinophilin's tumor suppressor function].

  2012cites this paper
• Selective interactions of spinophilin with the C-terminal domains of the δ- and μ-opioid receptors and G proteins differentially modulate opioid receptor signaling.

  2012cites this paper
• Spinophilin: a new tumor suppressor at 17q21.

  2012cites this paper
• A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling.

  2012cites this paper
• Protein Phosphatase 1γ Isoforms Linked Interactions in the Brain

  2012cites this paper
• Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation.

  2012cites this paper
• Modulation of monoamine receptors by adaptor proteins and lipid rafts: role in some effects of centrally acting drugs and therapeutic agents.

  2011cites this paper
• Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice

  2011cites this paper
• Molecular mechanisms underlying sexual reward.

  2011cites this paper
• Multiscale imaging characterization of dopamine transporter knockout mice reveals regional alterations in spine density of medium spiny neurons.

  2011cites this paper
• The Role of the Anterior Cingulate Cortex and Neurabin in Anxiety- and Depression-like Behaviours

  2010influential citation
• Identification and Validation of Novel Spinophilin-associated Proteins in Rodent Striatum Using an Enhanced ex Vivo Shotgun Proteomics Approach*

  2010cites this paper
• Spinophilin directs Protein Phosphatase 1 specificity by blocking substrate binding sites

  2010cites this paper
• Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat.

  2010cites this paper
• Dendritic Protein Phosphatase Complexes

  2010cites this paper
• Δ FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters

  2009cites this paper
• Genetik und Pathobiochem

  2009cites this paper
• PPP1R9B (Neurabin 2): Involvement and dynamics in the NK immunological synapse

  2009cites this paper
• From promiscuity to precision: protein phosphatases get a makeover.

  2009cites this paper
• Actin and Actin-Binding Proteins: Masters of Dendritic Spine Formation, Morphology, and Function.

  2009cites this paper
• Dopamine D1 receptor activation induces tau phosphorylation via cdk5 and GSK3 signaling pathways.

  2009cites this paper
• Spinophilin participates in information transfer at immunological synapses

  2008cites this paper
• Influenza A Virus Infection and NMDA receptor function

  2008cites this paper
• Influenza A virus infection and NMDA receptor function : A behavioral and molecular study of relevance for schizophrenia

  2008cites this paper
• Association of Protein Phosphatase 1γ1 with Spinophilin Suppresses Phosphatase Activity in a Parkinson Disease Model*

  2008cites this paper
• Synaptic plasticity in the basal ganglia: a similar code for physiological and pathological conditions.

  2008cites this paper
• Structure–function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin

  2008cites this paper
• A sensitizing d‐amphetamine regimen induces long‐lasting spinophilin protein upregulation in the rat striatum and limbic forebrain

  2008cites this paper
• Selective targeting of the 1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin

  2008cites this paper
• Dendritic spine dynamics--a key role for kalirin-7.

  2008cites this paper
• Multiple actions of spinophilin regulate mu opioid receptor function.

  2008cites this paper
• Neurabin Contributes to Hippocampal Long-Term Potentiation and Contextual Fear Memory

  2008cites this paper
• Postsynaptic targeting of protein kinases and phosphatases

  2008cites this paper
• Structural characterization of the neurabin sterile alpha motif domain

  2007cites this paper
• [Actin cytoskeleton in dendritic spine].

  2007cites this paper
• Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration.

  2007cites this paper
• Differential Regulation of AMPA Receptor Trafficking by Neurabin-Targeted Synaptic Protein Phosphatase-1 in Synaptic Transmission and Long-Term Depression in Hippocampus

  2007cites this paper
• Spinophilin/neurabin reciprocally regulate signaling intensity by G protein‐coupled receptors

  2007influential citation
• Neuronal polarity is regulated by a direct interaction between a scaffolding protein, Neurabin, and a presynaptic SAD-1 kinase in Caenorhabditis elegans

  2007influential citation
• Dopamine-dependent long term potentiation in the dorsal striatum is reduced in the R6/2 mouse model of Huntington's disease.

  2007cites this paper
• Genomewide suggestive linkage of opioid dependence to chromosome 14q.

  2007cites this paper
• More than just synaptic building blocks: scaffolding proteins of the post‐synaptic density regulate dendritic patterning

  2007cites this paper
• Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory.

  2006cites this paper