The family-specific K-loop influences the microtubule on-rate but not the superprocessivity of kinesin-3 motors

The kinesin-3 family–specific, positively charged insert, the K-loop, in loop 12 of the motor domain plays a critical role in cargo transport by enhancing the initial interaction of cargo-bound dimeric motors with the microtubule. The replacement of the K-loop, however, does not abolish the superprocessive motion of this class of kinesin motors.

• Publication year

  2014

• Venue

  Molecular Biology of the Cell

• Publication date

  2014-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E14-01-0696PMID 24850887PMCID 4091829
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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