Isolation of human antibodies against the central DNA binding domain of p53 from an individual with colorectal cancer using antibody phage display.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Clinical Cancer Research

• Publication date

  2001-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11555596
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A new prognostic indicator for head and neck cancer--p53 serum antibodies?

  1999cited by this paper
• Generation of anti-p53 Fab fragments from individuals with colorectal cancer using phage display.

  1999cited by this paper
• Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments

  1999cited by this paper
• Idiotypic immunization induces immunity to mutated p53 and tumor rejection

  1998cited by this paper
• Characterization of a new intrabody directed against the N-terminal region of human p53

  1998cited by this paper
• Immunity to p53 induced by an idiotypic network of anti-p53 antibodies: generation of sequence-specific anti-DNA antibodies and protection from tumor metastasis.

  1998cited by this paper
• Analysis of the molecular basis of synovial rheumatoid factors in rheumatoid arthritis.

  1997cited by this paper
• Anti-acetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies.

  1997cited by this paper
• Characteristics of human antibody repertoires following active immune responses in vivo.

  1996cited by this paper
• p53: puzzle and paradigm.

  1996cited by this paper
• Allosteric Regulation of the Thermostability and DNA Binding Activity of Human p53 by Specific Interacting Proteins (*)

  1996cited by this paper
• Characterisation and clinicopathological correlates of serum anti-p53 antibodies in breast and colon cancer

  1996cited by this paper
• Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insights into antibody-peptide interactions.

  1995cited by this paper
• Antibodies against p53 are associated with poor prognosis of colorectal cancer.

  1995cited by this paper
• Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein.

  1995cited by this paper
• Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways.

  1994cited by this paper
• Database of p53 gene somatic mutations in human tumors and cell lines.

  1994cited by this paper
• Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

  1994cited by this paper
• Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.

  1994cited by this paper
• The relationship between serum p53 autoantibodies and characteristics of human breast cancer.

  1994cited by this paper
• Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

  1994cited by this paper
• Prevalence of serum antibodies against the p53 tumor suppressor gene protein in various cancers

  1994cited by this paper
• Cloning and sequencing of human immunoglobulin λ. gene segments

  1993cited by this paper
• Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface.

  1993influential reference
• Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation.

  1992cited by this paper
• Human wild-type p53 adopts a unique conformational and phosphorylation state in vivo during growth arrest of glioblastoma cells.

  1992cited by this paper
• Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.

  1992cited by this paper
• A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia.

  1992cited by this paper
• The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot.

  1992cited by this paper
• Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.

  1991cited by this paper
• A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.

  1991cited by this paper
• Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning.

  1991cited by this paper
• Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.

  1990cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Presence of circulating antibodies against cellular protein p53 in a notable proportion of children with B‐cell lymphoma

  1987cited by this paper
• Development of primary and secondary immune responses to mouse monoclonal antibodies used in the diagnosis and therapy of malignant neoplasms.

  1986cited by this paper
• Detection of antibodies against the cellular protein p53 in sera from patients with breast cancer

  1982cited by this paper

• Recent developments in antibody derivatives against colorectal cancer; A review.

  2020cites this paper
• Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket

  2019cites this paper
• Characterization of sentinel node-derived antibodies from breast cancer patients.

  2018cites this paper
• Simultaneous Extraction of DNA and RNA from Hepatocellular Carcinoma (Hep G2) Based on Silica-Coated Magnetic Nanoparticles.

  2017cites this paper
• Phage-fused epitopes from Leishmania infantum used as immunogenic vaccines confer partial protection against Leishmania amazonensis infection

  2015cites this paper
• Mimotope-Based Vaccines of Leishmania infantum Antigens and Their Protective Efficacy against Visceral Leishmaniasis

  2014cites this paper
• Bacteriophage Vehicles for Phage Display: Biology, Mechanism, and Application

  2014cites this paper
• Phage display—A powerful technique for immunotherapy

  2012cites this paper
• Phage display—A powerful technique for immunotherapy

  2012cites this paper
• PRODUCTION OF PORCINE SINGLE CHAIN VARIABLE FRAGMENT (SCFV) SELECTED AGAINST A RECOMBINANT FRAGMENT OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS NON STRUCTURAL PROTEIN 2

  2011cites this paper
• Phase II trial of anti‐idiotypic p53 peptides (Pentrys) plus granulocyte‐macrophage colony‐stimulating factor in patients with hormone‐refractory prostate cancer

  2007cites this paper
• Combinatorial Phage Antibody Libraries

  2006cites this paper
• Antibody Libraries from Immunized Repertoires

  2005cites this paper
• Phase I clinical trial of a human idiotypic p53 vaccine in patients with advanced malignancy.

  2004cites this paper
• Receptor for the globular heads of C1q (gC1q‐R, p33, hyaluronan‐binding protein) is preferentially expressed by adenocarcinoma cells

  2004cites this paper