Bryostatin-1 attenuates TNF-induced epithelial barrier dysfunction: role of novel PKC isozymes.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  American Journal of Physiology - Gastrointestinal and Liver Physiology

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPGI.00214.2002PMID 12505880
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protein kinase C regulates endocytosis and recycling of E-cadherin.

  2002cited by this paper
• Protein Kinase C Signaling Regulates ZO-1 Translocation and Increased Paracellular Flux of T84 Colonocytes Exposed toClostridium difficile Toxin A*

  2002cited by this paper
• Intracellular transport mechanisms of signal transducers.

  2002cited by this paper
• Phorbol 12-myristate 13-Acetate Inhibits Death Receptor-mediated Apoptosis in Jurkat Cells by Disrupting Recruitment of Fas-associated Polypeptide with Death Domain*

  2002cited by this paper
• Protein Kinase C (cid:2) Is Required for Macrophage Activation and Defense Against Bacterial Infection

  2001cited by this paper
• Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

  2001cited by this paper
• Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

  2001cited by this paper
• Roles of tumor necrosis factor p55 and p75 receptors in TNF-alpha-induced vascular permeability.

  2001cited by this paper
• Anti-tumor necrosis factor monoclonal antibody therapy for gastrointestinal Behçet's disease: a case report.

  2001cited by this paper
• Protein Kinase Cε Is Required for Macrophage Activation and Defense Against Bacterial Infection

  2001cited by this paper
• Urogenital distribution of a mouse membrane-associated prostaglandin E(2) synthase.

  2001cited by this paper
• Interleukin-2 Receptor β Subunit-dependent and -independent Regulation of Intestinal Epithelial Tight Junctions*

  2001cited by this paper
• Protein Kinase C Regulates the Phosphorylation and Cellular Localization of Occludin*

  2001cited by this paper
• Protein kinase epsilon dampens the secretory response of model intestinal epithelia during ischemia.

  2001cited by this paper
• Roles of tumor necrosis factor p55 and p75 receptors in TNF-α-induced vascular permeability

  2001influential reference
• The role of protein kinase C isozymes in TNF-α-induced cytotoxicity to a rat intestinal epithelial cell line

  2001cited by this paper
• Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial.

  2001cited by this paper
• Regulation of epithelial transport and barrier function by distinct protein kinase C isoforms.

  2001cited by this paper
• The role of protein kinase C isozymes in TNF-alpha-induced cytotoxicity to a rat intestinal epithelial cell line.

  2001cited by this paper
• Gastroesophageal reflux disease in monozygotic and dizygotic twins.

  2001cited by this paper
• Protein kinase ϵ dampens the secretory response of model intestinal epithelia during ischemia

  2001cited by this paper
• Transmembrane TNF-α, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease

  2001cited by this paper
• Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets.

  2000cited by this paper
• Organization of choroid plexus epithelial and endothelial cell tight junctions and regulation of claudin‐1, ‐2 and ‐5 expression by protein kinase C

  2000cited by this paper
• Effect of TNF alpha and IFN gamma on epithelial barrier function in rat rectum in vitro.

  2000cited by this paper
• Claudins regulate the intestinal barrier in response to immune mediators.

  2000cited by this paper
• Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway

  2000cited by this paper
• Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-alpha (TNF-alpha ) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-alpha.

  2000cited by this paper
• Protein kinase C-alpha mediates endothelial barrier dysfunction induced by TNF-alpha.

  2000cited by this paper
• Serine phosphorylation of p60 tumor necrosis factor receptor by PKC-delta in TNF-alpha-activated neutrophils.

  2000cited by this paper
• Functional Dichotomy of Protein Kinase C (PKC) in Tumor Necrosis Factor-α (TNF-α) Signal Transduction in L929 Cells

  2000cited by this paper
• Protein kinase C-α mediates endothelial barrier dysfunction induced by TNF-α

  2000cited by this paper
• Serine phosphorylation of p60 tumor necrosis factor receptor by PKC-δ in TNF-α-activated neutrophils

  2000cited by this paper
• Synergistic effects of interferon gamma and tumour necrosis factor alpha on T84 cell function.

  1999cited by this paper
• Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.

  1999cited by this paper
• Synergistic e V ects of interferon ã and tumour necrosis factor á on T 84 cell function

  1999cited by this paper
• PKC-dependent regulation of transepithelial resistance : roles of MLC and MLC kinase

  1999cited by this paper
• TNF-α Induces Actin Cytoskeleton Reorganization in Glomerular Epithelial Cells Involving Tyrosine Phosphorylation of Paxillin and Focal Adhesion Kinase

  1999cited by this paper
• Protein kinase C activation downregulates the expression and function of the basolateral Na+/K+/2Cl− cotransporter

  1999cited by this paper
• Resistance to TNF-α cytotoxicity can be achieved through different signaling pathways in rat mesangial cells.

  1999cited by this paper
• TNF-aInducesActinCytoskeleton Reorganization inGlomerularEpithelial Cells Involving Tyrosine Phosphorylation ofPaxillin andFocalAdhesionKinase

  1999cited by this paper
• PKC-ε regulates basolateral endocytosis in human T84 intestinal epithelia: role of F-actin and MARCKS.

  1999cited by this paper
• Evidence That Protein Kinase Cε Mediates Phorbol Ester Inhibition of Calphostin C- and Tumor Necrosis Factor-α-induced Apoptosis in U937 Histiocytic Lymphoma Cells*

  1998cited by this paper
• Secretion imbalance between tumour necrosis factor and its inhibitor in inflammatory bowel disease

  1998cited by this paper
• Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2, but not TIMP-1, inhibit shedding of tumor necrosis factor-alpha receptors in a human colon adenocarcinoma (Colo 205) cell line.

  1998cited by this paper
• Evidence that protein kinase Cepsilon mediates phorbol ester inhibition of calphostin C- and tumor necrosis factor-alpha-induced apoptosis in U937 histiocytic lymphoma cells.

  1998cited by this paper
• Phorbol 12-myristate 13-acetate down-regulates Na,K-ATPase independent of its protein kinase C site: decrease in basolateral cell surface area.

  1997cited by this paper
• Protein Kinase C-α Activity Modulates Transepithelial Permeability and Cell Junctions in the LLC-PK1 Epithelial Cell Line*

  1997cited by this paper
• Superantigen activation of immune cells evokes epithelial (T84) transport and barrier abnormalities via IFN-gamma and TNF alpha: inhibition of increased permeability, but not diminished secretory responses by TGF-beta2.

  1997cited by this paper
• Stimulation of protein kinase C activity by tumor necrosis factor-α in bovine bronchial epithelial cells.

  1997cited by this paper
• Regulation of Tight Junction Resistance in T84 Monolayers by Elevation in Intracellular Ca2+: A Protein Kinase C Effect

  1996cited by this paper
• Regulated assembly of tight junctions by protein kinase C.

  1995cited by this paper
• Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

  1995cited by this paper
• Reversible disassembly of an intestinal epithelial monolayer by prolonged exposure to phorbol ester.

  1994cited by this paper
• Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor forms.

  1994cited by this paper
• Tumor necrosis factor receptor-mediated signaling pathways

  1994cited by this paper
• Na(+)-K(+)-2Cl- cotransport and Cl- secretion evoked by heat-stable enterotoxin is microfilament dependent in T84 cells.

  1993cited by this paper
• Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

  1992cited by this paper
• Mobilizable intracellular pool of p55 (type I) tumor necrosis factor receptors in human neutrophils

  1992cited by this paper
• Protein kinase C activity of colonic mucosa in ulcerative colitis.

  1992cited by this paper
• Effect of tumor necrosis factor on epithelial tight junctions and transepithelial permeability.

  1990cited by this paper
• Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. Enhancement of TNF receptor synthesis by protein kinase A and transmodulation of receptors by protein kinase C

  1989cited by this paper
• Tumor necrosis factor receptors and cytocidal activity are down-regulated by activators of protein kinase C.

  1988cited by this paper
• Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha.

  1987cited by this paper
• Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators

  1987cited by this paper

• Bryostatins 1 and 3 inhibit TRPM8 and modify TRPM8- and TRPV1-mediated lung epithelial cell responses to a proinflammatory stimulus via protein kinase C

  2025cites this paper
• Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation

  2022cites this paper
• Neutrophils and Platelets: Immune Soldiers Fighting Together in Stroke Pathophysiology

  2021cites this paper
• Regulation of Death Receptor Signaling by S-Palmitoylation and Detergent-Resistant Membrane Micro Domains—Greasing the Gears of Extrinsic Cell Death Induction, Survival, and Inflammation

  2021cites this paper
• Protective effects of lactic acid bacteria on gut epithelial barrier dysfunction are Toll like receptor 2 and protein kinase C dependent.

  2020cites this paper
• Lessons in Modeling, Preventing, and Treating Neural Injury: Improving Bench-to- Bedside Translation

  2013cites this paper
• A simple reporter assay for screening claudin-4 modulators.

  2012cites this paper
• Bryostatin-1 promotes long-term potentiation via activation of PKCα and PKCε in the hippocampus.

  2012cites this paper
• Tight Junctions and the Intestinal Barrier

  2012cites this paper
• Increase in the Tight Junction Protein Claudin-1 in Intestinal Inflammation

  2011cites this paper
• Paracellular permeability is increased by basal lipopolysaccharide in a primary culture of colonic epithelial cells; an effect prevented by an activator of Toll-like receptor-2

  2011cites this paper
• TNF-α potentiates lysophosphatidic acid-induced COX-2 expression via PKD in human colonic myofibroblasts.

  2011cites this paper
• Physiological determinants of the pulmonary filtration coefficient.

  2008cites this paper
• Endothelial PKCδ activation attenuates neutrophil transendothelial migration

  2008cites this paper
• Opposing regulation of the tight junction protein claudin-2 by interferon-gamma and interleukin-4.

  2008cites this paper
• Opposing Regulation of the Tight Junction Protein Claudin-2 by Interferon-γ and Interleukin-4

  2008cites this paper
• Association for Academic Surgery, 2006 Opposing Regulation of the Tight Junction Protein Claudin-2 by Interferon- and Interleukin-4 1

  2008cites this paper
• Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.

  2007cites this paper
• Probiotics and commensals reverse TNF-alpha- and IFN-gamma-induced dysfunction in human intestinal epithelial cells.

  2006cites this paper
• CHAPTER 61 – Tight Junctions and the Intestinal Barrier

  2006cites this paper
• θ Isoform of Protein Kinase C Alters Barrier Function in Intestinal Epithelium through Modulation of Distinct Claudin Isotypes: A Novel Mechanism for Regulation of Permeability

  2005influential citation
• Role of protein kinase C in intestinal ischemic preconditioning.

  2005cites this paper
• Role of protein kinase C in intestinal ischemic preconditioning1,2

  2005cites this paper
• Thin and strong! The bioengineering dilemma in the structural and functional design of the blood-gas barrier.

  2005cites this paper
• Interferon-γ and Tumor Necrosis Factor-α Synergize to Induce Intestinal Epithelial Barrier Dysfunction by Up-Regulating Myosin Light Chain Kinase Expression

  2005cites this paper
• Interferon- (cid:1) and Tumor Necrosis Factor- (cid:2) Synergize to Induce Intestinal Epithelial Barrier Dysfunction by Up-Regulating Myosin Light Chain Kinase Expression

  2005cites this paper
• Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression.

  2005cites this paper
• Theta-isoform of PKC is required for alterations in cytoskeletal dynamics and barrier permeability in intestinal epithelium: a novel function for PKC-theta.

  2004cites this paper
• oll-Like Receptor 2 Enhances ZO-1 – Associated Intestinal pithelial Barrier Integrity Via Protein Kinase C

  2004cites this paper
• θ-Isoform of PKC is required for alterations in cytoskeletal dynamics and barrier permeability in intestinal epithelium: a novel function for PKC-θ

  2004cites this paper
• Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C.

  2004cites this paper
• Increased epithelial uptake of protein antigens in the ileum of Crohn’s disease mediated by tumour necrosis factor α

  2004cites this paper
• Thoughts on the pulmonary blood-gas barrier.

  2003cites this paper
• Thickness of the blood-gas barrier in premature and 1-day-old newborn rabbit lungs.

  2003cites this paper
• Induction of cIAP-2 in Human Colon Cancer Cells through PKCδ/NF-κB*

  2003cites this paper
• Probiotics and Commensals Reverse TNF-α– and IFN-γ–Induced Dysfunction in Human Intestinal Epithelial Cells

  2003cites this paper
• Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B.

  2003cites this paper
• Intestinal barrier function

  2002cites this paper