Concerted action of Helios and Ikaros controls the expression of the inositol 5‐phosphatase SHIP

No abstract is available for this paper.

• Publication year

  2010

• Venue

  European Journal of Immunology

• Publication date

  2010-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/eji.200940002PMID 20602434
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Helios Deficiency Has Minimal Impact on T Cell Development and Function1

  2009cited by this paper
• Eos Mediates Foxp3-Dependent Gene Silencing in CD4+ Regulatory T Cells

  2009cited by this paper
• Ikaros and chromatin regulation in early hematopoiesis.

  2007cited by this paper
• Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

  2007cited by this paper
• Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

  2007cited by this paper
• Predominant Interaction of Both Ikaros and Helios with the NuRD Complex in Immature Thymocytes*

  2007cited by this paper
• Aiolos Controls Gene Conversion and Cell Death in DT40 B Cells

  2007cited by this paper
• Loss of Pax5 promotes plasma cell differentiation.

  2006cited by this paper
• DT40 mutants: a model to study transcriptional regulation of B cell development and function.

  2006cited by this paper
• Ikaros has a crucial role in regulation of B cell receptor signaling

  2006cited by this paper
• Transgenic Expression of Helios in B Lineage Cells Alters B Cell Properties and Promotes Lymphomagenesis1

  2005cited by this paper
• Avian Helios and Evolution of the Ikaros Family

  2004cited by this paper
• Survival of Resting Mature B Lymphocytes Depends on BCR Signaling via the Igα/β Heterodimer

  2004cited by this paper
• Chromatin Immunoprecipitation for Determining the Association of Proteins with Specific Genomic Sequences In Vivo

  2004cited by this paper
• Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer.

  2004cited by this paper
• B cell receptor signal strength determines B cell fate

  2004cited by this paper
• Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor.

  2003cited by this paper
• Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignancies

  2003cited by this paper
• Regulation of the phospholipase C-γ2 pathway in B cells

  2002cited by this paper
• Deletion of immunoglobulin β in developing B cells leads to cell death

  2002cited by this paper
• Deletion of immunoglobulin beta in developing B cells leads to cell death.

  2002cited by this paper
• Haematopoietic cell-fate decisions, chromatin regulation and ikaros

  2002cited by this paper
• Regulation of B-cell signal transduction by adaptor proteins

  2002cited by this paper
• Decision making in the immune system: Regulation of B-cell fate by antigen-receptor signals

  2002cited by this paper
• BLNK: molecular scaffolding through ‘cis’‐mediated organization of signaling proteins

  2002cited by this paper
• Ikaros is critical for B cell differentiation and function

  2002cited by this paper
• The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21.

  2001cited by this paper
• Mutant loxP vectors for selectable marker recycle and conditional knock-outs

  2001cited by this paper
• Bilevel control of B‐cell activation by the inositol 5‐phosphatase SHIP

  2000cited by this paper
• A Dual Role for Src Homology 2 Domain–Containing Inositol-5-Phosphatase (Ship) in Immunity

  2000cited by this paper
• Differential Regulation of B Cell Development, Activation, and Death by the Src Homology 2 Domain–Containing 5′ Inositol Phosphatase (Ship)

  2000cited by this paper
• Regulation of the phospholipase C‐γ2 pathway in B cells

  2000cited by this paper
• Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

  1999cited by this paper
• BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells.

  1999cited by this paper
• BLNK Required for Coupling Syk to PLCγ2 and Rac1-JNK in B Cells

  1999cited by this paper
• Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.

  1998cited by this paper
• Aiolos regulates B cell activation and maturation to effector state.

  1998cited by this paper
• SHIP modulates immune receptor responses by regulating membrane association of Btk.

  1998cited by this paper
• Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

  1998cited by this paper
• Role of the inositol phosphatase SHIP in B cell receptor-induced Ca2+ oscillatory response.

  1998cited by this paper
• Erratum: Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaos at centromeric heterochromatin (Genes and Development (1998) 12 (782-796))

  1998cited by this paper
• Activation of phospholipase Cγ by PI 3‐kinase‐induced PH domain‐mediated membrane targeting

  1998cited by this paper
• Phosphatidylinositol‐3,4,5‐trisphosphate (PtdIns‐3,4,5‐P3)/Tec kinase‐dependent calcium signaling pathway: a target for SHIP‐mediated inhibitory signals

  1998cited by this paper
• The Inositol Polyphosphate 5-Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling

  1998cited by this paper
• Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.

  1998cited by this paper
• Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5‐trisphosphate receptors in signal transduction through the B‐cell antigen receptor

  1997cited by this paper
• Zinc finger‐mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development.

  1996cited by this paper
• The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.

  1996cited by this paper
• A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2

  1996cited by this paper
• Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation.

  1996cited by this paper
• The Ikaros gene is required for the development of all lymphoid lineages.

  1994cited by this paper
• A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

  1991cited by this paper

• The Inositol-5-Phosphatase SHIP1: Expression, Regulation and Role in Acute Lymphoblastic Leukemia

  2025cites this paper
• Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway

  2024cites this paper
• INPP5D/SHIP1: Expression, Regulation and Roles in Alzheimer’s Disease Pathophysiology

  2023cites this paper
• Apigenin Targets MicroRNA-155, Enhances SHIP-1 Expression, and Augments Anti-Tumor Responses in Pancreatic Cancer

  2022cites this paper
• The Potential Function of Super Enhancers in Human Bone Marrow Mesenchymal Stem Cells during Osteogenic Differentiation

  2021cites this paper
• Ikaros-Associated Diseases: From Mice to Humans and Back Again

  2021cites this paper
• Coexpression of Helios in Foxp3+ Regulatory T Cells and Its Role in Human Disease

  2021cites this paper
• IRF4 modulates the response to BCR activation in chronic lymphocytic leukemia regulating IKAROS and SYK

  2021cites this paper
• Deregulation of Ikaros expression in B‐1 cells: New insights in the malignant transformation to chronic lymphocytic leukemia

  2019cites this paper
• Changes in bursal B cells in chicken during embryonic development and early life after hatching

  2018cites this paper
• The effect of PU.1 knockdown on gene expression and function of mast cells

  2018cites this paper
• Regulation of B cell development by transcription factors IRF4 and BACH2

  2017cites this paper
• Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif

  2016cites this paper
• The Continuing Flight of Ikaros

  2016cites this paper
• The Ikaros family of zinc-finger proteins

  2016cites this paper
• Rôle des facteurs de transcription Eos et Helios dans la biologie des cellules T régulatrices

  2015cites this paper
• IRF4 Deficiency Leads to Altered BCR Signalling Revealed by Enhanced PI3K Pathway, Decreased SHIP Expression and Defected Cytoskeletal Responses

  2015cites this paper
• Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings

  2014cites this paper
• Master transcription factors and mediator establish super-enhancers at key cell identity genes.

  2013cites this paper
• Phenotypic and Functional Properties of Helios+ Regulatory T Cells

  2012cites this paper
• Phosphoinositide phosphatases: just as important as the kinases.

  2012cites this paper
• A novel strategy for modulation of MDSC to enhance cancer immunotherapy

  2012cites this paper
• Ikaros in B cell development and function.

  2011cites this paper
• Gene Interaction Network Regulates Plasma Cell Differentiation

  2011cites this paper
• Murine Pancreatic Adenocarcinoma Dampens SHIP-1 Expression and Alters MDSC Homeostasis and Function

  2011cites this paper
• Ikaros isoforms: The saga continues.

  2011cites this paper
• Zinc finger structure-function in Ikaros World Journal of Biological Chemistry

  2011cites this paper
• The Ikaros gene family: transcriptional regulators of hematopoiesis and immunity.

  2011cites this paper
• Role of SHIP in cancer.

  2011cites this paper
• Zinc finger structure-function in Ikaros Marvin A Payne.

  2011cites this paper
• Signaling Proteins and Transcription Factors in Normal and Malignant Early B Cell Development

  2011cites this paper
• Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs.

  2011cites this paper
• Alternate pathways for Bcl6‐mediated regulation of B cell to plasma cell differentiation

  2011cites this paper
• Genetic regulatory networks in avian B cells

  2010cites this paper