Management of Differentiated Thyroid Cancer in Pregnancy

In young women, differentiated thyroid cancer is the second most common malignancy diagnosed around the time of pregnancy. Management of thyroid cancer during pregnancy poses distinct challenges due to concerns regarding maternal and fetal well-being. In most cases surgery can be safely delayed until after delivery and with adequate management and outcome of pregnancy in women with thyroid cancer is excellent. Ideally these patients should be managed by a multidisciplinary team, and management plan should be determined by a consensus between the patient and the healthcare team.

• Publication year

  2011

• Venue

  Journal of Thyroid Research

• Publication date

  2011-05-25

• Fields of study

  Medicine

• Identifiers
  DOI 10.4061/2011/549609PMID 21687597PMCID 3112517
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CA : A Cancer Journal for Clinicians

  2011cited by this paper
• Clinical and molecular features of differentiated thyroid cancer diagnosed during pregnancy.

  2010cited by this paper
• Care of the pregnant thyroid cancer patient

  2010cited by this paper
• Evaluation of the thyroid function of healthy pregnant women by five different hormone assays.

  2010cited by this paper
• Thyroid and parathyroid surgery in pregnancy

  2010cited by this paper
• Thyroid hormone early adjustment in pregnancy (the THERAPY) trial.

  2010cited by this paper
• Higher maternal TSH levels in pregnancy are associated with increased risk for miscarriage, fetal or neonatal death.

  2009cited by this paper
• Outcomes following thyroid and parathyroid surgery in pregnant women.

  2009cited by this paper
• Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer

  2009influential reference
• Correlations of free thyroid hormones measured by tandem mass spectrometry and immunoassay with thyroid-stimulating hormone across 4 patient populations.

  2009cited by this paper
• Free T4 immunoassays are flawed during pregnancy.

  2009cited by this paper
• Therapeutic Administration of 131I for Differentiated Thyroid Cancer: Radiation Dose to Ovaries and Outcome of Pregnancies

  2008cited by this paper
• Free thyroid hormones in serum by direct equilibrium dialysis and online solid-phase extraction--liquid chromatography/tandem mass spectrometry.

  2008cited by this paper
• Differentiated Thyroid Cancer: Radiation Dose to Ovaries and Outcome of Pregnancies

  2008cited by this paper
• Risk of thyroid cancer after exposure to fertility drugs: results from a large Danish cohort study.

  2007cited by this paper
• Cancer Statistics, 2007

  2007cited by this paper
• Subclinical Hyperthyroidism and Pregnancy Outcomes

  2006cited by this paper
• Subclinical Hypothyroidism and Pregnancy Outcomes

  2005cited by this paper
• Induction of Thyroid Papillary Carcinoma Cell Proliferation by Estrogen Is Associated with an Altered Expression of Bcl‐xL

  2005cited by this paper
• Thyroid-Stimulating Hormone in Singleton and Twin Pregnancy: Importance of Gestational Age–Specific Reference Ranges

  2005cited by this paper
• Timing and Magnitude of Increases in Levothyroxine Requirements During Pregnancy in Women With Hypothyroidism

  2005cited by this paper
• Trimester-Specific Changes in Maternal Thyroid Hormone, Thyrotropin, and Thyroglobulin Concentrations During Gestation: Trends and Associations Across Trimesters in Iodine Sufficiency

  2004cited by this paper
• The reference range and within-person variability of thyroid stimulating hormone during the first and second trimesters of pregnancy

  2004cited by this paper
• Cancer associated with obstetric delivery: results of linkage with the California cancer registry.

  2003cited by this paper
• Improving outcomes in head and neck cancer.

  2003cited by this paper
• Procedure guideline for therapy of thyroid disease with (131)iodine.

  2002cited by this paper
• Patterns of care for patients with primary differentiated carcinoma of the thyroid gland treated in Germany during 1996

  2000cited by this paper
• Reproductive and hormonal risk factors for thyroid cancer in Los Angeles County females.

  1999cited by this paper
• Radioiodine and Pregnancy

  1999cited by this paper
• Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child.

  1999cited by this paper
• A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985‐1995

  1998cited by this paper
• An audit of the management of thyroid cancer in a district general hospital

  1998cited by this paper
• Outcome of differentiated thyroid cancer diagnosed in pregnant women.

  1997cited by this paper
• Exposure to radioactive iodine-131 for scintigraphy or therapy does not preclude pregnancy in thyroid cancer patients.

  1996cited by this paper
• Regulatory analysis on criteria for the release of patients administered radioactive material

  1994cited by this paper
• Positive correlation between parity and incidence of thyroid cancer: New evidence based on complete Norwegian birth cohorts

  1991cited by this paper
• Increased need for thyroxine during pregnancy in women with primary hypothyroidism

  1990cited by this paper
• Cancer statistics

  1989cited by this paper
• In vitro effects of estrogen on tgb and c-myc gene expression in normal and neoplastic human thyroids.

  1989cited by this paper
• Thyroid cancer among young women related to prior thyroid disease and pregnancy history.

  1987cited by this paper
• Decreased serum thyroglobulin levels in the late stage of pregnancy.

  1986cited by this paper
• Incidence of thyroid cancer in women in relation to reproductive and hormonal factors.

  1984cited by this paper
• Theoretical consideration of the effects of dilution on estimates of free thyroid hormones in serum.

  1984cited by this paper
• Surgery during pregnancy and fetal outcome.

  1980cited by this paper

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  2022cites this paper
• A narrative review of pregnancy after malignancies in young women that don't originate in the female genital organs or in the breast.

  2021cites this paper
• Agreement between thyroid nodules ultrasound and cytology of fine needle aspiration (FNA) based on TIRADS and Bethesda system

  2021cites this paper
• Impact of pregnancy on papillary thyroid carcinoma prognosis

  2021influential citation
• Management of Endocrinopathies in Pregnancy: A Review of Current Evidence

  2019cites this paper
• Pregnancy in papillary thyroid cancer survivors

  2018cites this paper
• Clinical therapy and management of differentiated thyroid cancer in pregnant women

  2018influential citation
• Thyroid Disease During Pregnancy

  2017cites this paper
• Thyroid Cancer and Pregnancy

  2016cites this paper
• Program for Absorbed Dose Evaluation and Risk Assessment of Fetus Following Maternal Radioiodine Therapy

  2016cites this paper
• Timing of Surgical Management of Papillary Thyroid Cancer Diagnosed during Pregnancy

  2016cites this paper
• A review on thyroid cancer during pregnancy: Multitasking is required

  2016cites this paper
• Progesterone Upregulates Gene Expression in Normal Human Thyroid Follicular Cells

  2015cites this paper
• Thyroid Papillary Cancer Triggered by Pregnancy: Case Report

  2014cites this paper
• Clinical guidelines for management of thyroid nodule and cancer during pregnancy.

  2014cites this paper
• Clinical guidelines for management of thyroid nodule and cancer during pregnancy

  2014cites this paper
• Synchrotron pair halo and echo emission from blazars in the cosmic web: application to extreme TeV blazars

  2014cites this paper
• Papillary thyroid cancer in a gravid woman.

  2014cites this paper
• Guía clínica para el manejo del nódulo tiroideo y cáncer de tiroides durante el embarazo

  2013cites this paper
• Maternal Tumours Associated with and Influenced by Pregnancy

  2012cites this paper
• ENDOCRINOLOGÍA Y NUTRICIÓN

  year unknowncites this paper