Transient reduction of the ocular perfusion pressure and the oscillatory potentials of the ERG.

PURPOSE To evaluate the changes of the Oscillatory Potentials (OPs) of Electroretinogram (ERG) caused by short-term hypertension in human subjects, and their relationship with ocular perfusion pressure (OPP). METHODS Suction cup technique in 12 normal volunteers with OPs simultaneously recording. RESULTS Scotopic and photopic OPs were altered during OPP drop. Scotopic OPs showed more sensitiveness, with higher reduction (from 21% to 47%), when compared to the basal value, than in photopic recordings (from 14% to 34%). In both conditions, the relationship between OPP and OPs presented a steady amplitude before the trough after the +30 step, and rapid recovery after OPP normalisation. ANOVA and correlation analysis confirmed the data. CONCLUSION The ERG OPs seemed to reflect the OPP modification. The features of OPs amplitudes suggest involvement of the retinal autoregulation mechanism and support development for further clinical studies.

• Publication year

  2005

• Venue

  Vision Research

• Publication date

  2005-05-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.VISRES.2004.10.027PMID 15733966
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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