Chronic blockade of angiotensin II AT1-receptors increased cell-to-cell communication, reduced fibrosis and improved impulse propagation in the failing heart

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of the Renin-Angiotensin-Aldosterone System

• Publication date

  2006-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.3317/jraas.2006.038PMID 17318788
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence.

  2006cited by this paper
• Working outside the system: an update on the unconventional behavior of the renin-angiotensin system components.

  2005cited by this paper
• Heart failure: how important is cellular sequestration? The role of the renin-angiotensin-aldosterone system.

  2004cited by this paper
• Gap junction alterations in human cardiac disease.

  2004cited by this paper
• Heart failure: how important is cellular sequestration? The role of the renin-angiotensin-aldosterone system.

  2004cited by this paper
• Effects of angiotensin II type 1 receptor antagonist on electrical and structural remodeling in atrial fibrillation.

  2003cited by this paper
• The Cardiac Syncytium; An Overview

  2002cited by this paper
• Chronic effects of endothelin‐1 and angiotensin‐II on gap junctions and intercellular communication in cardiac cells

  2002cited by this paper
• Prorenin-Induced Myocyte Proliferation: No Role for Intracellular Angiotensin II

  2002cited by this paper
• Regulation of Cardiac Collagen: Angiotensin and Cross-Talk With Local Growth Factors

  2001cited by this paper
• The angiotensin II type 1 receptor and receptor-associated proteins

  2001cited by this paper
• Chronic administration of losartan plus hydrochlorothiazide improves vascular status in young cardiomyopathic hamsters.

  2001cited by this paper
• Cardiac arrhythmias: the possible role of the renin-angiotensin system

  2001cited by this paper
• Gap junction remodeling in hypertrophied left ventricles of aortic-banded rats: prevention by angiotensin II type 1 receptor blockade.

  2001cited by this paper
• Drug therapy

  2000cited by this paper
• Angiotensin II mediated signal transduction. Important role of tyrosine kinases.

  2000cited by this paper
• Chapter 27: Gap Junctional Communication in the Failing Heart

  1999cited by this paper
• Functional role of c-Src in gap junctions of the cardiomyopathic heart.

  1999cited by this paper
• Quantitative analysis of dual whole-cell voltage-clamp determination of gap junctional conductance

  1998cited by this paper
• Effects of angiotensin II on expression of the gap junction channel protein connexin43 in neonatal rat ventricular myocytes.

  1998cited by this paper
• Electrophysiologic and morphologic abnormalities in the failing heart: effect of enalapril on the electrical properties.

  1997cited by this paper
• Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block.

  1997cited by this paper
• Renin-angiotensin system and cell communication in the failing heart.

  1996cited by this paper
• Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts.

  1995cited by this paper
• Spontaneously active cells isolated from the sino-atrial and atrio-ventricular nodes of the rabbit heart.

  1981influential reference
• A rapid technique for the isolation and purification of adult cardiac muscle cells having respiratory control and a tolerance to calcium.

  1976cited by this paper

• The electrophysiology of ventricular cell pairs

  2025cites this paper
• AI-based Predictive Signaling Pathway Profiling in Cardiac Fibrosis Suggests a Novel Combinatorial Treatment Strategy

  2025cites this paper
• Myocardial Recovery in Recent Onset Dilated Cardiomyopathy: Role of CDCP1 and Cardiac Fibrosis

  2023cites this paper
• Hypertension Induces Pro-arrhythmic Cardiac Connexome Disorders: Protective Effects of Treatment

  2023cites this paper
• Retinol exerts therapeutic effect on myocardial infarction through regulation of immune inflammatory cells and Cx43 expression

  2022cites this paper
• ‘Youthful’ phenotype of c-Kit+ cardiac fibroblasts

  2022cites this paper
• Fibroblast‐mediated intercellular crosstalk in the healthy and diseased heart

  2021cites this paper
• Phosphorylation of GATA4 at serine 105 is required for left ventricular remodelling process in angiotensin II‐induced hypertension in rats

  2020cites this paper
• Antihypertensive and Antifibrosis Effects of Acupuncture at PC6 Acupoints in Spontaneously Hypertensive Rats and the Underlying Mechanisms

  2020cites this paper
• Gap-134, a Connexin43 activator, prevents age-related development of ventricular fibrosis in Scn5a+/- mice.

  2020cites this paper
• Cardiac Tissue Remodeling in Healthy Aging: The Road to Pathology.

  2020cites this paper
• Chronic Intermittent Hypoxia Triggers a Senescence-like Phenotype in Human White Preadipocytes

  2020cites this paper
• A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity.

  2020cites this paper
• Effects of losartan and atorvastatin on the development of early posttraumatic joint stiffness in a rat model

  2019cites this paper
• Modulation of connective tissue growth factor and activin receptor 2b function in cardiac hypertrophy and fibrosis

  2019cites this paper
• DDDT_A_204135 2603..2618

  2019cites this paper
• Angiotensin peptide synthesis and cyclic nucleotide modulation in sympathetic stellate ganglia

  2019cites this paper
• Cardiac fibrosis: new insights into the pathogenesis

  2018cites this paper
• Renin Angiotensin Aldosterone System and Heart Function

  2017cites this paper
• Serum level of transforming growth factor beta 1 is associated with left atrial voltage in patients with chronic atrial fibrillation

  2017cites this paper
• Myocardial fibrosis in congenital and pediatric heart disease

  2017influential citation
• Na+-H+ exchanger and proton channel in heart failure associated with Becker and Duchenne muscular dystrophies.

  2017cites this paper
• Invited Commentary.

  2017cites this paper
• Vascular Endothelial Growth Factor Prevents Endothelial-to-Mesenchymal Transition in Hypertrophy.

  2017cites this paper
• The Role of β-adrenergic Signalling and Natriuretic Peptide Receptors in Cardiac Myofibroblast Proliferation and Differentiation

  2016cites this paper
• Integrins and integrin-related proteins in cardiac fibrosis.

  2016cites this paper
• Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

  2016cites this paper
• Antifibrotic therapies to control cardiac fibrosis

  2016cites this paper
• Can heart function lost to disease be regenerated by therapeutic targeting of cardiac scar tissue?

  2016cites this paper
• May the fibrosis be with you: Is discoidin domain receptor 2 the receptor we have been looking for?

  2016cites this paper
• Myocardial Regenerative Medicine

  2016cites this paper
• Managing dystrophinopathic cardiomyopathy

  2016cites this paper
• Molecular basis and functional significance of Angiotensin II-induced increase in Discoidin Domain Receptor 2 gene expression in cardiac fibroblasts.

  2016cites this paper
• Can we protect from malignant arrhythmias by modulation of cardiac cell-to-cell coupling?

  2015cites this paper
• X-Linked Dilated Cardiomyopathy: A Cardiospecific Phenotype of Dystrophinopathy

  2015cites this paper
• The role of extracellular matrix in age-related conduction disorders: a forgotten player?

  2015cites this paper
• Getting to the heart of the matter: new insights into cardiac fibrosis.

  2015cites this paper
• Atrial fibrillation and obesity: characterization of electro-structural atrial substrate with sustained obesity and reversal upon weight reduction.

  2014cites this paper
• Enhanced Angiotensin II-Induced Cardiac and Aortic Remodeling in ACE2 Knockout Mice

  2013cites this paper
• An Anthelmintic Drug, Pyrvinium Pamoate, Thwarts Fibrosis and Ameliorates Myocardial Contractile Dysfunction in a Mouse Model of Myocardial Infarction

  2013cites this paper
• Combined effects of up- and downstream therapies on atrial fibrillation in a canine rapid stimulation model.

  2012cites this paper
• Reduced Cx43 Expression Triggers Increased Fibrosis Due to Enhanced Fibroblast Activity

  2012cites this paper
• Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43

  2011cites this paper
• δ-Sarcoglycan-deficient muscular dystrophy: from discovery to therapeutic approaches

  2011cites this paper
• Novel aspects of angiotensin II action in the heart. Implications to myocardial ischemia and heart failure.

  2011cites this paper
• Renin angiotensin system and cardiovascular disease

  2010cites this paper
• Potential Therapeutic Targets for Cardiac Fibrosis: TGF&bgr;, Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation

  2010cites this paper
• Chapter 2 – Neuroendocrine control of cardiovascular function: Physiology and pharmacology

  2010cites this paper
• Andrew Leask CCN 2 , and PDGF , Partners in Fibroblast Activation , Angiotensin , Endothelin , β Potential Therapeutic Targets for Cardiac Fibrosis : TGF

  2010cites this paper
• Potential Therapeutic Targets for Cardiac Fibrosis TGF (cid:1) , Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation

  2010cites this paper
• Potential Therapeutic Targets for Cardiac Fibrosis TGF (cid:1) , Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation

  2010cites this paper
• Potential Therapeutic Targets for Cardiac Fibrosis TGF (cid:1) , Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation

  2010cites this paper
• Potential Therapeutic Targets for Cardiac Fibrosis TGF (cid:1) , Angiotensin, Endothelin, CCN2, and PDGF, Partners in Fibroblast Activation

  2010cites this paper
• Influência do inibidor da enzima conversora da angiotensina na remodelação cardíaca induzida pela exposição à fumaça do cigarro

  2009cites this paper
• Opposite effects of angiotensin II and angiotensin (1-7) on impulse propagation, excitability and cardiac arrhythmias. Is the overexpression of ACE2 arrhythmogenic?

  2009cites this paper
• Structural and Electrophysiological Remodeling of the Failing Heart

  2009influential citation
• Current understanding and management of dilated cardiomyopathy in Duchenne and Becker muscular dystrophy

  2009cites this paper
• Targeting the angiotensin pathway in idiopathic pulmonary fibrosis.

  2008cites this paper
• Anti-arrhythmic Drug Therapy for Atrial Fibrillation: Current Anti-arrhythmic Drugs, Investigational Agents, and Innovative Approaches

  2008cites this paper
• The Effects of Renin–angiotensin System Inhibition on Regression of Encapsulating Peritoneal Sclerosis

  2008cites this paper
• Anti-arrhythmic drug therapy for atrial fibrillation: current anti-arrhythmic drugs, investigational agents, and innovative approaches.

  2008cites this paper
• The left atrium, atrial fibrillation, and the risk of stroke in hypertensive patients with left ventricular hypertrophy

  2008cites this paper
• Targeting the angiotensin pathway in idiopathic pulmonary fibrosis

  2008cites this paper
• Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

  2008cites this paper
• Research progress in mechanism and treatment of myocardial fibrosis

  year unknowncites this paper