Copper(I) and copper(II) binding to β-amyloid 16 (Aβ16) studied by electrospray ionization mass spectrometry.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Metallomics

• Publication date

  2010-07-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/c004693kPMID 21072347
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Direct quantification of protein-metal ion affinities by electrospray ionization mass spectrometry.

  2010cited by this paper
• Alzheimer's disease, metal ions and metal homeostatic therapy.

  2009cited by this paper
• Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-beta peptide.

  2009cited by this paper
• The role of copper in cysteine oxidation: study of intra- and inter-molecular reactions in mass spectrometry.

  2009cited by this paper
• Interaction of beta-amyloid(1-40) peptide with pairs of metal ions: An electrospray ion trap mass spectrometric model study.

  2009cited by this paper
• Electrochemical and Conformational Consequences of Copper (CuI and CuII) Binding to β‐Amyloid(1–40)

  2009cited by this paper
• Functional electrospray emitters.

  2009cited by this paper
• Photocatalytic redox reactions for in-source peptide fragmentation.

  2009cited by this paper
• Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.

  2008cited by this paper
• Structural studies of copper(I) complexes of amyloid-beta peptide fragments: formation of two-coordinate bis(histidine) complexes.

  2008cited by this paper
• Mechanistic studies of Cu(II) binding to amyloid-beta peptides and the fluorescence and redox behaviors of the resulting complexes.

  2008cited by this paper
• The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptide.

  2008cited by this paper
• Amyloid beta conformation in aqueous environment.

  2008cited by this paper
• On-line electrogeneration of copper-peptide complexes in microspray mass spectrometry

  2008cited by this paper
• Substrate mediated reduction of copper-amyloid-beta complex in Alzheimer's disease.

  2008cited by this paper
• Metal swap between Zn7-metallothionein-3 and amyloid-beta-Cu protects against amyloid-beta toxicity.

  2008cited by this paper
• Amyloid β Conformation in Aqueous Environment

  2008cited by this paper
• The redox chemistry of the Alzheimer's disease amyloid beta peptide.

  2007cited by this paper
• Redox Chemistry of Copper–Amyloid‐β: The Generation of Hydroxyl Radical in the Presence of Ascorbate is Linked to Redox‐Potentials and Aggregation State

  2007cited by this paper
• The redox chemistry of the Alzheimer's disease amyloid β peptide

  2007cited by this paper
• Electrochemical generation of Cu(I) complexes in aqueous solutions studied by on-line mass spectrometry

  2007cited by this paper
• A century-old debate on protein aggregation and neurodegeneration enters the clinic

  2006cited by this paper
• Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis).

  2006cited by this paper
• C alpha-C backbone fragmentation dominates in electron detachment dissociation of gas-phase polypeptide polyanions.

  2005cited by this paper
• The metallobiology of Alzheimer's disease.

  2003cited by this paper
• Neurodegenerative disease: Amyloid pores from pathogenic mutations

  2002cited by this paper
• Climate change (Communication arising): Recent temperature trends in the Antarctic

  2002cited by this paper
• Metals and neuroscience.

  2000cited by this paper
• Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly:  implications for amyloid fibril formation and materials science.

  2000cited by this paper
• Effects of anions on the positive ion electrospray ionization mass spectra of peptides and proteins.

  1994cited by this paper

• Protein-Driven Copper Redox Regulation: Uncovering the Role of Disulphide Bonds and Allosteric Modulation

  2025cites this paper
• Investigating Cu(I) binding to model peptides of N-terminal Aβ isoforms.

  2024cites this paper
• Cu and Zn Interactions with Peptides Revealed by High-Resolution Mass Spectrometry

  2022cites this paper
• Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer's Disease.

  2022cites this paper
• The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer’s-linked amyloid-β oligomers in mice

  2020cites this paper
• Curcumin in Health and Diseases: Alzheimer’s Disease and Curcumin Analogues, Derivatives, and Hybrids

  2020influential citation
• Exploration of the Potential Role for Aβ in Delivery of Extracellular Copper to Ctr1.

  2020cites this paper
• Nitration of amyloid-β peptide (1-42) as a protective mechanism for the amyloid-β peptide (1-42) against copper ion toxicity.

  2019cites this paper
• Cu and Zn interactions with Aβ peptides: consequence of coordination on aggregation and formation of neurotoxic soluble Aβ oligomers.

  2019cites this paper
• Matrix-assisted nanoelectrospray mass spectrometry for soft ionization of metal(i)-protein complexes.

  2019cites this paper
• Using N-Terminal Coordination of Cu(II) and Ni(II) to Isolate the Coordination Environment of Cu(I) and Cu(II) Bound to His13 and His14 in Amyloid-β(4-16).

  2019cites this paper
• Stoichiometry of Heavy Metal Binding to Peptides Involved in Alzheimer's Disease: Mass Spectrometric Evidence.

  2019cites this paper
• An inorganic overview of natural Aβ fragments: Copper(II) and zinc(II)-mediated pathways

  2018cites this paper
• Copper reduction and dioxygen activation in Cu-amyloid beta peptide complexes: insight from molecular modelling.

  2018cites this paper
• Copper Binding Induces Nitration of NPY under Nitrative Stress: Complicating the Role of NPY in Alzheimer's Disease.

  2018cites this paper
• Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

  2017influential citation
• Influence of membrane environments and copper ions on the structural features of amyloidogenic proteins correlated to neurodegeneration

  2016cites this paper
• Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer’s Drug Discovery

  2016cites this paper
• Probing Molecular Interactions in Metal-Abeta Complexes and Supramolecular Coiled Coil Assemblies Using Electron Spin Resonance

  2015cites this paper
• On the generation of OH· radical species from H2O2 by Cu(I) amyloid beta peptide model complexes: a DFT investigation

  2015cites this paper
• Analytical Chemistry at the Laboratoire d'Electrochimie Physique et Analytique.

  2015cites this paper
• Neurodegenerative diseases – Understanding their molecular bases and progress in the development of potential treatments

  2015cites this paper
• Copper(II) and nickel(II) binding sites of peptide containing adjacent histidyl residues.

  2015cites this paper
• Capturing a Reactive State of Amyloid Aggregates

  2014cites this paper
• ESEEM Analysis of Multi-Histidine Cu(II)-Coordination in Model Complexes, Peptides, and Amyloid-β

  2014cites this paper
• Tandem mass spectrometry in metallomics and the involving role of ICP-MS detection: a review.

  2014cites this paper
• Antioxidant promotion of tyrosine nitration in the presence of copper(II).

  2013cites this paper
• Mass spectrometric methods for monitoring redox processes in electrochemical cells

  2013cites this paper
• Electrochemical Pseudo-Titration of Water-Soluble Antioxidants

  2013cites this paper
• Does Aluminium Bind to Histidine? An NMR Investigation of Amyloid β12 and Amyloid β16 Fragments

  2013cites this paper
• Phenol ring nitration induced by the unprecedented reduction of the Cu(II) centre by nitrogen dioxide.

  2013cites this paper
• Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease.

  2013cites this paper
• Copper and oxidative stress in the pathogenesis of Alzheimer's disease.

  2012cites this paper
• Structural characterization of Cu2+, Ni2+ and Zn2+ binding sites of model peptides associated with neurodegenerative diseases

  2012cites this paper
• Inhibitory action of macrocyclic platiniferous chelators on metal-induced Aβ aggregation

  2012cites this paper
• Coordination of redox active metal ions to the amyloid precursor protein and to amyloid-β peptides involved in Alzheimer disease. Part 1: An overview

  2012cites this paper
• Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)

  2012cites this paper
• Aggregation pathways of the amyloid β(1-42) peptide depend on its colloidal stability and ordered β-sheet stacking.

  2012cites this paper
• Copper-catalyzed tyrosine nitration.

  2011cites this paper
• Measurement of the interaction of aqueous copper(II) with a model amyloid-β protein fragment — Interference from buffers

  2011cites this paper
• Interfacial complexation reactions of Sr2+ with octyl(phenyl)-N,N-diisobutylcarbamoylmethylphosphine oxide for understanding its extraction in reprocessing spent nuclear fuels.

  2011cites this paper
• Phosphorylation of α-Synuclein at Y 125 and S 129 Alters Its Metal Binding Properties : Implications for Understanding the Role of α-Synuclein in the Pathogenesis of Parkinson ’ s Disease and Related Disorders

  2011cites this paper
• LEPA: from proteomics to energy conversion.

  2011cites this paper
• Beta-amyloid oligomers: recent developments

  2011cites this paper
• Pushing the frontiers of first-principles based computer simulations of chemical and biological systems.

  2011cites this paper
• Interactions of Zn(II) and Cu(II) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity.

  2011cites this paper
• Phosphorylation of α-Synuclein at Y125 and S129 alters its metal binding properties: implications for understanding the role of α-Synuclein in the pathogenesis of Parkinson's Disease and related disorders.

  2011cites this paper