The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphia-positive acute lymphoblastic leukemia: a seven-year update of the GIMEMA 0496 trial.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Haematologica

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 16531262
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Review on

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  2002cited by this paper
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  2002cited by this paper
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  2002influential reference
• BCR/ABL genes and leukemic phenotype: from molecular mechanisms to clinical correlations

  2002cited by this paper
• Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.

  2001cited by this paper
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  1999cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1994cited by this paper
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  1993cited by this paper
• Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance.

  1991cited by this paper
• The molecular genetics of Philadelphia chromosome-positive leukemias.

  1988cited by this paper
• Minimal Residual Disease in Acute Leukemia

  1984cited by this paper
• An international system for human cytogenetic nomenclature

  1978cited by this paper
• Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative Group

  1976cited by this paper

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  2018cites this paper
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  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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