Beneficial effects of long-term selective endothelin type A receptor blockade in canine experimental heart failure.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Cardiovascular Research

• Publication date

  1998-09-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0008-6363(98)00169-2PMID 9861299
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelin-1

  2020cited by this paper
• Discovery

  2008cited by this paper
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  1997cited by this paper
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  1996cited by this paper
• Short-term hemodynamic effects of endothelin receptor blockade in dogs with chronic heart failure.

  1996cited by this paper
• Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart.

  1996cited by this paper
• Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists.

  1996cited by this paper
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  1996cited by this paper
• Inhibition of myocardial endothelin pathway improves long-term survival in heart failure

  1996cited by this paper
• Biatrial appendage hypertrophy but not ventricular hypertrophy: a unique feature of canine pacing-induced heart failure.

  1996cited by this paper
• Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure.

  1995cited by this paper
• Atrial wall tension changes and the release of atrial natriuretic factor on relief of cardiac tamponade.

  1995cited by this paper
• Both ETA and ETB receptors mediate contraction to endothelin-1 in human blood vessels.

  1994cited by this paper
• Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan).

  1994cited by this paper
• Report of the Task Force on Research in Heart Failure.

  1994cited by this paper
• Recovery of attenuated baroreflex sensitivity in conscious dogs after reversal of pacing induced heart failure.

  1994cited by this paper
• Endothelin-stimulated secretion of natriuretic peptides by rat atrial myocytes is mediated by endothelin A receptors.

  1994cited by this paper
• Endothelin in human congestive heart failure.

  1994cited by this paper
• Left ventricular myocardial blood flow, metabolism, and effects of treatment with enalapril: further insights into the mechanisms of canine experimental pacing-induced heart failure.

  1993cited by this paper
• Endothelin in thoracic inferior vena caval constriction model of heart failure.

  1992cited by this paper
• Elevated Endothelin‐1 in Heart Failure and Loss of Normal Response to Postural Change

  1992cited by this paper
• The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo.

  1992cited by this paper
• Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor.

  1992cited by this paper
• Low-dose endothelin-1 potentiates volume-induced secretion of atrial natriuretic factor.

  1992cited by this paper
• Evaluation of indices of left ventricular contractility and relaxation in evolving canine experimental heart failure.

  1992cited by this paper
• Impact of enalapril therapy on in vitro coronary artery responsiveness in pacing-induced heart failure.

  1992cited by this paper
• Response of Atrial Natriuretic Factor to Acute and Chronic Increases of Atrial Pressures in Experimental Heart Failure in Dogs: Role of Changes in Heart Rate, Atrial Dimension, and Cardiac Tissue Concentration

  1991cited by this paper
• Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.

  1991cited by this paper
• Sequential echocardiographic-Doppler assessment of left ventricular remodelling and mitral regurgitation during evolving experimental heart failure.

  1991cited by this paper
• Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

  1990cited by this paper
• Endothelin in experimental congestive heart failure in the anesthetized dog.

  1990cited by this paper
• Increased endothelin in experimental heart failure.

  1990cited by this paper
• Cloning and expression of a cDNA encoding an endothelin receptor

  1990cited by this paper
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  1989cited by this paper
• The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

  1989cited by this paper
• Recovery from heart failure: structural and functional analysis in a canine model.

  1988cited by this paper
• Early recovery from heart failure: insights into the pathogenesis of experimental chronic pacing-induced heart failure.

  1988cited by this paper
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  1988cited by this paper
• Positive chronotropic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide

  1988cited by this paper
• A novel potent vasoconstrictor peptide produced by vascular endothelial cells

  1988cited by this paper
• Rapid ventricular pacing in the dog: pathophysiologic studies of heart failure.

  1986cited by this paper
• Canine left ventricular mass estimation by two-dimensional echocardiography.

  1983cited by this paper
• Two-dimensional echocardiographic determination of left atrial emptying volume: a noninvasive index in quantifying the degree of nonrheumatic mitral regurgitation.

  1983cited by this paper
• Cross-sectional echocardiography

  1982cited by this paper
• Cross‐sectional Echocardiography 1. Analysis of Mathematic Models for Quantifying Mass of the Left Ventricle in Dogs

  1979cited by this paper

• Management of Chronic Congestive Heart Failure Caused by Myxomatous Mitral Valve Disease in Dogs: A Narrative Review from 1970 to 2020

  2022cites this paper
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  2017cites this paper
• Clinical and Hemodynamic Effects of Endothelin Receptor Antagonists in Patients With Heart Failure.

  2017cites this paper
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• Autonomic Dysregulation as a Therapeutic Target for Acute HF

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  2012cites this paper
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  2010cites this paper
• Calcium Signaling: Receptors, Effectors, and Other Signaling Pathways

  2010cites this paper
• Endothelin Receptor Antagonists and Acute Heart Failure Syndromes

  2008cites this paper
• Cardiac sympathetic nerve terminal function in congestive heart failure

  2007cites this paper
• Endothelin receptor antagonists.

  2006cites this paper
• Tachycardia‐Induced Cardiomyopathy: A Review of Literature

  2005cites this paper
• Clinical effects of endothelin receptor antagonism with bosentan in patients with severe chronic heart failure: results of a pilot study.

  2005cites this paper
• Endothelin Receptor Antagonists: Clinical Realities and Future Directions

  2005cites this paper
• New Pharmacological Strategies in Chronic Heart Failure

  2004cites this paper
• Significance of recently identified peptides in hypertension: endothelin, natriuretic peptides, adrenomedullin, leptin.

  2004cites this paper
• The potential of endothelin antagonism as a therapeutic approach

  2004cites this paper
• New Pharmacological Strategies in Chronic Heart Failure

  2004cites this paper
• Will endothelin receptor antagonists have a role in heart failure?

  2003cites this paper
• The endothelin system and its role in acute myocardial infarction.

  2003cites this paper
• Role of endothelins in congestive heart failure.

  2003cites this paper
• [New expansion of endothelin research: perspectives for clinical application of endothelin-receptor antagonists].

  2003cites this paper
• The endothelin system in pulmonary hypertension.

  2003cites this paper
• Selective endothelin receptor blockade reverses mitochondrial dysfunction in canine heart failure.

  2002cites this paper
• The role of endothelin in the pathogenesis of heart failure

  2002cites this paper
• Role of endothelin-1 in cardiac and vascular dysfunction in streptozotocin-diabetic rats : effects of chronic endothelin receptor blockade

  2002cites this paper
• Hemodynamic and Neurohumoral Effects of Selective Endothelin A (ETA) Receptor Blockade in Chronic Heart Failure: The Heart Failure ETA Receptor Blockade Trial (HEAT)

  2002cites this paper
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  2002cites this paper
• Reversal of left ventricular remodeling: role of the endothelin pathway.

  2002cites this paper
• Chronic endothelin-1 blockade reduces sympathetic nerve activity in rabbits with heart failure.

  2001cites this paper
• Endothelin Receptor Antagonists and Cardiovascular Diseases of Aging

  2001cites this paper
• Endothelin A Receptor Antagonists in Congestive Heart Failure: Blocking the Beast while Leaving the Beauty Untouched?

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• Overview: The Role of Potassium Channels in Cardiac Arrhythmias

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• Endothelin-1 and Pulmonary Hypertension

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• Endothelins Within the Liver and the Gastrointestinal System

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  2001cites this paper
• Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension

  2001cites this paper
• Endothelin receptor antagonists in congestive heart failure: a new therapeutic principle for the future?

  2001cites this paper
• The role of endothelin receptor antagonists in cardiovascular pharmacotherapy

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• Basic and therapeutic relevance of endothelin-mediated regulation.

  2001cites this paper
• Therapeutic Potential for Endothelin Receptor Antagonists in Cardiovascular Disorders

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• Endothelin and Its Inhibitors

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• The Regulation of Sympathetic Outflow in Heart Failure

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• The role of endothelins and their receptors in heart failure.

  2001cites this paper
• Endothelins and Endothelin Receptor Antagonists: Therapeutic Considerations for a Novel Class of Cardiovascular Drugs

  2000cites this paper
• Chronic therapy with an ET receptor antagonist in conscious dogs A / B during progression of congestive heart failure 2 1 Intracellular Ca regulation and nitric oxide mediated coronary relaxation

  2000cites this paper
• Endothelin receptor antagonists and their developing role in cardiovascular therapeutics.

  2000cites this paper
• An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis.

  2000cites this paper
• Chronic endothelin blockade in dogs with pacing-induced heart failure: possible modulation of sympathoexcitation.

  2000cites this paper
• Chronic therapy with an ET(A/B) receptor antagonist in conscious dogs during progression of congestive heart failure. Intracellular Ca(2+) regulation and nitric oxide mediated coronary relaxation.

  2000cites this paper
• Activation of cardiorenal and pulmonary tissue endothelin-1 in experimental heart failure.

  2000cites this paper
• Endothelin-1 and endothelin receptor antagonists in cardiovascular remodeling.

  1999cites this paper
• Cardiac endothelin and big endothelin in right-heart hypertrophy due to monocrotaline-induced pulmonary hypertension in rat.

  1999cites this paper
• Pacing-induced heart failure: a model to study the mechanism of disease progression and novel therapy in heart failure.

  1999influential citation
• Pharmacology of the EndothelinA Receptor Antagonist: LU 135252

  1998cites this paper