Gnotobiotic piglets develop thrombotic microangiopathy after oral infection with enterohemorrhagic Escherichia coli.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Clinical Pathology

• Publication date

  2002-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1309/UMW9-D06Q-M94Q-JGH2PMID 12219778
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Thrombotic microangiopathy, hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: Rare manifestations of Russell’s viper (Daboia russelii) envenoming in Sri Lanka

  2021cited by this paper
• Rapid Detection of Enterohemorrhagic Escherichia coliby Real-Time PCR with Fluorescent Hybridization Probes

  2001cited by this paper
• Response to single and divided doses of Shiga toxin-1 in a primate model of hemolytic uremic syndrome.

  2001cited by this paper
• Thrombotic microangiopathy, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura.

  2001cited by this paper
• Escherichia coli O157:H7 Causes More-Severe Systemic Disease in Suckling Piglets than in Colostrum-Deprived Neonatal Piglets

  2000cited by this paper
• Cattle lack vascular receptors for Escherichia coli O157:H7 Shiga toxins.

  2000cited by this paper
• Escherichia coli 0157:H7 Strains That Express Shiga Toxin (Stx) 2 Alone Are More Neurotropic for Gnotobiotic Piglets Than Are Isotypes Producing Only Stx1 or Both Stx1 and Stx2

  2000cited by this paper
• Characterization of the baboon responses to Shiga-like toxin: descriptive study of a new primate model of toxic responses to Stx-1.

  1999cited by this paper
• EnterohemorrhagicEscherichia coli (EHEC) in Pediatric Hemolytic-Uremic Syndrome: A Prospedtive Study in Germany and Austria*

  1999cited by this paper
• Large Animal Internal Medicine: Diseases of Horses, Cattle, Sheep, and Goats

  1996cited by this paper
• Proposed new nomenclature for SLT (VT) family

  1996cited by this paper
• The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection

  1995cited by this paper
• Escherichia coli 0157:H7: Clinical, Diagnostic, and Epidemiological Aspects of Human Infection

  1995cited by this paper
• Interaction of Verotoxins with Glycosphingolipids

  1993cited by this paper
• Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis.

  1992cited by this paper
• Studies with enteroaggregative Escherichia coli in the gnotobiotic piglet gastroenteritis model

  1992cited by this paper
• Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum

  1992cited by this paper
• Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7

  1989cited by this paper
• Verotoxin receptor glycolipid in human renal tissue.

  1989cited by this paper
• Purification of Shiga toxin and Shiga-like toxins I and II by receptor analog affinity chromatography with immobilized P1 glycoprotein and production of cross-reactive monoclonal antibodies

  1989cited by this paper
• Studies in gnotobiotic piglets on non-O157:H7 Escherichia coli serotypes isolated from patients with hemorrhagic colitis.

  1988cited by this paper
• Illnesses associated with Escherichia coli O157:H7 infections. A broad clinical spectrum.

  1988cited by this paper
• Comparison in Gnotobiotic Pigs of Lesions Caused by Verotoxigenic and Non-verotoxigenic Escherichia coli

  1988cited by this paper
• Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.

  1988cited by this paper
• [Gnotobiotic delivery and raising of piglets of the Göttinger miniature swine breed].

  1988cited by this paper
• Gnotobiotic delivery and raising of piglets of the Göttinger miniature swine breed

  1988cited by this paper
• Escherichia coli strains isolated from pigs with edema disease produce a variant of Shiga-like toxin II

  1987cited by this paper
• Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities

  1986cited by this paper
• Hemorrhagic colitis associated with a rare Escherichia coli serotype.

  1983cited by this paper
• A glycolipid antigen associated with Burkitt lymphoma defined by a monoclonal antibody.

  1983cited by this paper
• Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools.

  1983cited by this paper
• Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines

  1983cited by this paper
• Postnatal development of the pig kidney: ultrastucure of the glomerulus and the proximal tubule.

  1980cited by this paper
• Pathologic changes in edema disease of swine.

  1969cited by this paper

• Gut Microbiota-Based Immunotherapy: Engineered Escherichia coli Nissle 1917 for Oral Delivery of Glypican-1 in Pancreatic Cancer

  2025cites this paper
• Efficacy of EHEC gold nanoparticle vaccines evaluated with the Shiga toxin-producing Citrobacter rodentium mouse model

  2023cites this paper
• Are biters sick? Health status of tail biters in comparison to control pigs

  2023cites this paper
• Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistance

  2023cites this paper
• Targeting the innate repair receptor axis via erythropoietin or pyroglutamate helix B surface peptide attenuates hemolytic-uremic syndrome in mice

  2022cites this paper
• Multi-omics approaches for comprehensive analysis and understanding of the immune response in the miniature pig breed

  2022cites this paper
• A One Health Perspective for Defining and Deciphering Escherichia coli Pathogenic Potential in Multiple hosts.

  2021cites this paper
• Valid Presumption of Shiga Toxin-Mediated Damage of Developing Erythrocytes in EHEC-Associated Hemolytic Uremic Syndrome

  2020cites this paper
• The pig as a model for immunology research

  2020cites this paper
• EFFECT OF POINT MUTATIONS ON THE TOXICITY OF SHIGA TOXIN A1 SUBUNIT

  2019cites this paper
• Development of a Human Primary Intestine Chip and Identification of Species-Specific Microbiome Metabolites Enhancing Enterohemorrhagic E. Coli Pathogenesis

  2019cites this paper
• Modeling Hemolytic-Uremic Syndrome: In-Depth Characterization of Distinct Murine Models Reflecting Different Features of Human Disease

  2018cites this paper
• Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7

  2017influential citation
• Effect of antibiotic, probiotic, and human rotavirus infection on colonisation dynamics of defined commensal microbiota in a gnotobiotic pig model.

  2017cites this paper
• Efficacy of Urtoxazumab (TMA-15 Humanized Monoclonal Antibody Specific for Shiga Toxin 2) Against Post-Diarrheal Neurological Sequelae Caused by Escherichia coli O157:H7 Infection in the Neonatal Gnotobiotic Piglet Model

  2017influential citation
• A phase trial of the oral Lactobacillus casei vaccine polarizes Th2 cell immunity against transmissible gastroenteritis coronavirus infection

  2016cites this paper
• Translational value of animal models of kidney failure.

  2015cites this paper
• Investigating the Contributions of Leukocyte Responses and Kidney Cell Stress on Shiga- Toxin Pathogenesis

  2015cites this paper
• The identification and characterization of bacterial and host epithelial factors involved in the pathogenesis of invasive Francisella tularensis and extracellular enteropathogenic E. coli (EPEC)

  2015cites this paper
• Animal Models of Enterohemorrhagic Escherichia coli Infection

  2014cites this paper
• Neurological involvement in children with E. coli O104:H4-induced hemolytic uremic syndrome

  2014cites this paper
• Probiotics: properties, examples, and specific applications.

  2013cites this paper
• Differential virulence of clinical and bovine-biased enterohemorrahgic E . coli 1 O 157 : H 7 genotypes in piglet and Dutch Belted rabbit models 2 3

  2013cites this paper
• Patterns in early diffusion-weighted MRI in children with haemolytic uraemic syndrome and CNS involvement

  2012cites this paper
• Identification of specific miRNAs targeting proteins of the apical junctional complex that simulate the probiotic effect of E. coli Nissle 1917 on T84 epithelial cells.

  2012cites this paper
• A New Murine Model For Enterohemorrhagic Escherichia coli Infection Reveals That Actin Pedestal Formation Facilitates Mucosal Colonization and Lethal Disease: A Dissertation

  2012cites this paper
• Shiga Toxins and the Pathophysiology of Hemolytic Uremic Syndrome in Humans and Animals

  2012cites this paper
• Shiga toxin in enterohemorrhagic E.coli: regulation and novel anti-virulence strategies

  2012cites this paper
• Differential Virulence of Clinical and Bovine-Biased Enterohemorrhagic Escherichia coli O157:H7 Genotypes in Piglet and Dutch Belted Rabbit Models

  2011cites this paper
• Cross-Talk tra Bifidobacterium e intestino umano: impatto sulle attività health promoting

  2010cites this paper
• Zoonotic enterohemorrhagic Escherichia coli: A One Health perspective.

  2010cites this paper
• ADAMTS13 activity is decreased in a septic porcine model

  2010cites this paper
• Effects of Shiga toxin 2 on isolated porcine granulocytes

  2009influential citation
• Escherichia coli O157:H7 colonization in small domestic ruminants.

  2009influential citation
• Split immune response after oral vaccination of mice with recombinant Escherichia coli Nissle 1917 expressing fimbrial adhesin K88.

  2009cites this paper
• Cloning a Truncated Fragment (stx2a1) of the Shiga-Like Toxin 2A1 Subunit of EHEC O157:H7: Candidate Immunogen for a Subunit Vaccine

  2009cites this paper
• Escherichia coli Nissle 1917 for probiotic use in piglets: evidence for intestinal colonization

  2009influential citation
• Drug-inducible remote control of gene expression by probiotic Escherichia coli Nissle 1917 in intestine, tumor and gall bladder of mice.

  2009cites this paper
• Infections due to Escherichia and Shigella

  2008cites this paper
• Development of an experimental hemolytic uremic syndrome in rats

  2008cites this paper
• Effects of microbiota on GI health: gnotobiotic research.

  2008cites this paper
• Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.

  2008cites this paper
• Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of β-Glucosidase 2

  2007cites this paper
• Molecular mechanisms underlying the probiotic effects of Escherichia coli Nissle 1917 involve ZO‐2 and PKCζ redistribution resulting in tight junction and epithelial barrier repair

  2007cites this paper
• Impact of the rpoS genotype for acid resistance patterns of pathogenic and probiotic Escherichia coli

  2007cites this paper
• Differences in Virulence among Escherichia coli O157:H7 Strains Isolated from Humans during Disease Outbreaks and from Healthy Cattle

  2007influential citation
• Escherichia coli infections

  2006cites this paper
• Modulation of the gastrointestinal barrier function by probiotic Escherichia coli Nissle 1917

  2006cites this paper
• Effect of orally administered probiotic E. coli strain Nissle 1917 on intestinal mucosal immune cells of healthy young pigs.

  2006cites this paper
• The jejunal Peyer's patches are the major inductive sites of the F4-specific immune response following intestinal immunisation of pigs with F4 (K88) fimbriae.

  2006cites this paper
• Haemolytic-uraemic syndrome caused by a non-O157 : H7 Escherichia coli strain in experimentally inoculated dogs.

  2006cites this paper
• Intestinal immunity of Escherichia coli NISSLE 1917: a safe carrier for therapeutic molecules.

  2005cites this paper
• Shiga-Toxigenic Escherichia coli-Inoculated Neonatal Piglets Develop Kidney Lesions That Are Comparable to Those in Humans with Hemolytic-Uremic Syndrome

  2005cites this paper
• Shiga Toxin 1 Causes Direct Renal Injury in Rats

  2005cites this paper
• Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data.

  2005cites this paper
• Enterohaemorrhagic E. coli in veterinary medicine.

  2005cites this paper
• Shiga Toxin Binding to Isolated Porcine Tissues and Peripheral Blood Leukocytes

  2004influential citation
• Antibody Therapy in the Management of Shiga Toxin-Induced Hemolytic Uremic Syndrome

  2004cites this paper
• Lepirudin prevents lethal effects of Shiga toxin in a canine model

  2004cites this paper
• Colonisation and persistence of Escherichia coli 0157:H7 in the bovine gastro-intestinal tract

  2003cites this paper
• Comparative Pathogenicity of Escherichia coli O157 and Intimin-Negative Non-O157 Shiga Toxin-Producing E. coli Strains in Neonatal Pigs

  2003cites this paper
• The effect of inflammation on Shiga toxin absorption in vivo

  2003cites this paper
• Searching for a valid animal model of hemolytic uremic syndrome.

  2002cites this paper