In situ induction of dendritic cell–based T cell tolerance in humanized mice and nonhuman primates

K. Jung,Chung-Gyu Park,Yoo Kyung Jeon,H. Park,Young Larn Ban,H. Min,Eun Ji Kim,Ju ng-Hyun Kim,Byung Hyun Kang,Seung Pyo Park,Y. Bae,Il‐Hee Yoon,Yong-Hee Kim,Jae-Il Lee,Jung‐Sik Kim,Jun-Seop Shin,J. Yang,Sung Joo Kim,Emily Rostlund,W. Muller,S. Park

Published 2011 in Journal of Experimental Medicine

ABSTRACT

Administration of an ICAM-1–specific antibody arrests dendritic cells in a semi-immature state and facilitates antigen-specific T cell tolerance to islet allografts in humanized mice and Rhesus monkeys.

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