Short Review of Current Research on the Physiology and Pathology of Olfactory Detection

Most concepts related to physiology and pathology of olfaction has been related to abnormalities in neural function related to changes in central nervous system disorders or in disorders of olfactory nerves. While these events have been useful in understanding olfactory physiology and pathology most pathology of olfactory detection lies in problems related to olfactory receptor function not to the neural correlates per se. This brief review introduces pertinent information which relates to the role that olfactory receptors, their physiology and their pathology play in olfactory function.

• Publication year

  2016

• Venue

  Journal of Neurology and Neurophysiology

• Publication date

  2016-03-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4172/2155-9562.1000363
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Spatiotemporal Dynamics

  2017cited by this paper
• Increasing Nasal Mucus Sonic Hedgehog (Shh) Improves Human Olfaction

  2015cited by this paper
• Taste and smell function in chronic disease: a review of clinical and biochemical evaluations of taste and smell dysfunction in over 5000 patients at The Taste and Smell Clinic in Washington, DC.

  2013cited by this paper
• Olfactory Receptors

  2013cited by this paper
• Growth Factors in Olfaction

  2012cited by this paper
• An Open-Label Controlled Trial of Theophylline for Treatment of Patients With Hyposmia

  2009cited by this paper
• cAMP and cGMP in nasal mucus: relationships to taste and smell dysfunction, gender and age.

  2008cited by this paper
• cAMP and cGMP in nasal mucus related to severity of smell loss in patients with smell dysfunction.

  2008cited by this paper
• cGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO.

  2002cited by this paper
• Efficacy of exogenous oral zinc in treatment of patients with carbonic anhydrase VI deficiency.

  1999cited by this paper
• Transduction mechanisms in vertebrate olfactory receptor cells.

  1998cited by this paper
• A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway.

  1997cited by this paper
• Calcium Entry through Cyclic Nucleotide-Gated Channels in Individual Cilia of Olfactory Receptor Cells: Spatiotemporal Dynamics

  1997cited by this paper
• Information coding in the vertebrate olfactory system.

  1996cited by this paper
• Discrimination of molecular signals by the olfactory receptor neuron.

  1994cited by this paper
• Intracellular cyclic GMP receptor proteins

  1993cited by this paper
• Molecular messengers of olfaction.

  1992cited by this paper
• Zinc deficiency decreases the activity of calmodulin regulated cyclic nucleotide phosphodiesterases in vivo in selected rat tissues

  1988cited by this paper
• Zinc localization in taste bud membranes

  1983cited by this paper
• Defects in taste and smell recognition following temporal lobectomy.

  1977cited by this paper
• Hypogeusia, Dysgeusia, Hyposmia, and Dysosmia following Influenza-Like Infection

  1975cited by this paper
• Abnormalities of taste and smell after head trauma

  1974cited by this paper
• Idiopathic hypogeusia with dysgeusia, hyposmia, and dysosmia. A new syndrome.

  1971cited by this paper

• Sweet Taste Sensitivity and Its association with Serum Zinc Levels in Women with Premenstrual Syndrome

  2017cites this paper
• Laboratory Mice in Medical Research

  2016cites this paper