Effects of calcitonin gene-related peptide-(8-37) on withdrawal responses in rats with inflammation.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  European Journal of Pharmacology

• Publication date

  1998-04-24

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0014-2999(98)00102-2PMID 9653894
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The calcitonin gene-related peptide antagonist CGRP8-37 increases the latency to withdrawal responses bilaterally in rats with unilateral experimental mononeuropathy, an effect reversed by naloxone.

  1996cited by this paper
• Intrathecal CGRP8–37‐induced bilateral increase in hindpaw withdrawal latency in rats with unilateral inflammation

  1996cited by this paper
• Calcitonin gene-related peptide (8-37) does not antagonize calcitonin gene-related peptide in rat spinal cord.

  1996cited by this paper
• A calcitonin gene-related peptide receptor antagonist prevents the development of tolerance to spinal morphine analgesia

  1996cited by this paper
• Calcitonin gene-related peptide is involved in the spinal processing of mechanosensory input from the rat's knee joint and in the generation and maintenance of hyperexcitability of dorsal horn-neurons during development of acute inflammation.

  1996cited by this paper
• The spinal contribution of substance P to the generation and maintenance of inflammatory hyperalgesia in the rat

  1996cited by this paper
• Calcitonin gene‐related peptide content, basal outflow and electrically‐evoked release from monoarthritic rat spinal cord in vitro

  1996cited by this paper
• The role of dorsal root reflexes in neurogenic inflammation

  1995cited by this paper
• Tachykinins and calcitonin gene-related peptide (CGRP) as co-transmitters released from peripheral endings of sensory nerves.

  1995cited by this paper
• Spinal cord pharmacology of pain.

  1995cited by this paper
• Opioid antagonists naloxone, beta-funaltrexamine and naltrindole, but not nor-binaltorphimine, reverse the increased hindpaw withdrawal latency in rats induced by intrathecal administration of the calcitonin gene-related peptide antagonist CGRP8-37.

  1995cited by this paper
• Inflammatory mediators of pain.

  1995cited by this paper
• Tachykinins and Calcitonin Gene-Related Peptide

  1995cited by this paper
• Behavioral manifestations of an experimental model for peripheral neuropathy produced by spinal nerve ligation in the primate

  1994cited by this paper
• Substance P-, neurokinin A-, calcitonin gene-related peptide- and neuropeptide Y-like immunoreactivity (-LI) in rat knee joint synovial fluid during acute monoarthritis is not correlated with concentrations of neuropeptide-LI in cerebrospinal fluid and plasma.

  1994cited by this paper
• The calcitonin gene-related peptide antagonist CGRP8-37 increases the latency to withdrawal responses in rats.

  1994cited by this paper
• Inflammation and hyperalgesia: highlighting the team effort.

  1993cited by this paper
• Oxytocin modulates the effects of galanin in carrageenan-induced hyperalgesia in rats.

  1993cited by this paper
• Opioid control of the release of calcitonin gene-related peptide-like material from the rat spinal cord in vivo.

  1993cited by this paper
• Bilateral changes of substance P-, neurokinin A-, calcitonin gene-related peptide- and neuropeptide Y-like immunoreactivity in rat knee joint synovial fluid during acute monoarthritis.

  1993cited by this paper
• Effects of intrathecal antibodies to substance P, calcitonin gene‐related peptide and galanin on repeated cold stress‐induced hyperalgesia: comparison with carrageenan‐induced hyperalgesia

  1992cited by this paper
• Potent anti-inflammatory action of calcitonin gene-related peptide.

  1991cited by this paper
• Calcitonin gene related peptide.

  1991cited by this paper
• Facilitatory role of calcitonin gene-related peptide (CGRP) on excitation induced by substance P (SP) and noxious stimuli in rat spinal dorsal horn neurons. An iontophoretic study in vivo.

  1991cited by this paper
• Further evidence for ‘pain‐related’ behaviours in a model of unilateral peripheral mononeuropathy

  1990cited by this paper
• Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37).

  1989influential reference
• Antinociceptive effect of intrathecally administered antiserum against calcitonin gene-related peptide on thermal and mechanical noxious stimuli in experimental hyperalgesic rats.

  1989influential reference
• Opioid control of the in vitro release of calcitonin gene-related peptide from primary afferent fibres projecting in the rat cervical cord.

  1989cited by this paper
• Interactions between the tachykinins and calcitonin gene‐related peptide lead to the modulation of oedema formation and blood flow in rat skin

  1989cited by this paper
• Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat.

  1988cited by this paper
• A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

  1988cited by this paper
• Survey of distribution of substance P, vasoactive intestinal polypeptide, cholecystokinin, neurotensin, Met-enkephalin, bombesin and PHI in the spinal cord of cat, dog, sloth and monkey.

  1988cited by this paper
• Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat.

  1988cited by this paper
• Neuropeptides, inflammation, and motility

  1988cited by this paper
• Inflammatory oedema induced by synergism between calcitonin gene‐related peptide (CGRP) and mediators of increased vascular permeability

  1985cited by this paper
• Biphasic development of carrageenin edema in rats.

  1969cited by this paper
• Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs

  1962cited by this paper

• Potamotrygon motoro stingray venom induces both neurogenic and inflammatory pain behavior in rodents

  2018cites this paper
• Changes in Spinal Cord Following Inflammatory and Neuropathic Pain and the Effectiveness of Resiniferatoxin

  2016cites this paper
• Involvements of galanin and its receptors in antinociception in nucleus accumbens of rats with inflammatory pain.

  2015cites this paper
• Ablation and Regeneration of Peripheral and Central TRPV1 Expressing Nerve Terminals and the Consequence of Nociception

  2015cites this paper
• Antinociceptive properties of physalins from Physalis angulata.

  2014cites this paper
• Assessment of thermal sensitivity in rats using the thermal place preference test: description and application in the study of oxaliplatin-induced acute thermal hypersensitivity and inflammatory pain models

  2014cites this paper
• Evidence for anti-inflammatory and putative analgesic effects of a monoclonal antibody to calcitonin gene-related peptide.

  2013cites this paper
• Secondary and tertiary sulfonamides: a patent review (2008 – 2012)

  2013cites this paper
• Antagonism of 5-HT(2A) receptors inhibits the expression of pronociceptive mediator and enhances endogenous opioid mechanism in carrageenan-induced inflammation in rats.

  2011cites this paper
• Upregulation of adrenomedullin in the spinal cord and dorsal root ganglia in the early phase of CFA‐induced inflammation in rats

  2009cites this paper
• CGRP in Spinal Cord Pain Mechanisms

  2009cites this paper
• N‐terminal bis‐(2‐Chloroethyl)amino and Fluorosulphonyl Analogues of Calcitonin Gene‐Related Peptide(8‐37): Irreversible Antagonists at Calcitonin Gene‐Related Peptide Receptors

  2007influential citation
• Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain‐related sensitization of amygdala neurons

  2007cites this paper
• Design, Synthesis and Pharmacological Characterization of Novel Calcitonin Gene-Related Peptide Receptor Antagonists

  2006cites this paper
• Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP

  2006cites this paper
• Involvement of spinal neurokinins, excitatory amino acids, proinflammatory cytokines, nitric oxide and prostanoids in pain facilitation induced by Phoneutria nigriventer spider venom.

  2004cites this paper
• Muscle and brain changes of calcitonin gene-related peptide in experimentally induced unilateral rat masseter myositis.

  2004cites this paper
• Efeito nociceptivo induzido por fosfolipases A2 (FLA2 variantes Lys49 e Asp49) isoladas do veneno de serpentes Bothrops asper: caracterização dos mecanismos centrais e determinantes moleculares

  2004cites this paper
• Involvement of oxytocin in spinal antinociception in rats with inflammation.

  2003cites this paper
• Flurbiprofen inhibits capsaicin induced calcitonin gene related peptide release from rat spinal cord via an endocannabinoid dependent mechanism.

  2003cites this paper
• Role of calcitonin gene-related peptide and its antagonist on the evoked discharge frequency of wide dynamic range neurons in the dorsal horn of the spinal cord in rats.

  2002cites this paper
• Anti-nociceptive effect of neuropeptide Y in periaqueductal grey in rats with inflammation.

  2001cites this paper
• Crossed and uncrossed projections to the cat sacrocaudal spinal cord: III. Axons expressing calcitonin gene‐related peptide immunoreactivity

  2001cites this paper
• Functional calcitonin gene-related peptide subtype 2 receptors in porcine coronary arteries are identified as calcitonin gene-related peptide subtype 1 receptors by radioligand binding and reverse transcription-polymerase chain reaction.

  2001cites this paper
• A comparative study of the ability of calcitonin gene‐related peptide and adrenomedullin13–52 to modulate microvascular but not thermal hyperalgesia responses

  2000cites this paper
• Antinociceptive effects of calcitonin gene-related peptide injected into periaqueductal grey of rats with mononeuropathy.

  2000cites this paper
• Anti-nociceptive effects of calcitonin gene-related peptide in nucleus raphe magnus of rats: an effect attenuated by naloxone.

  2000cites this paper
• Effects of intrathecal galanin on nociceptive responses in rats with mononeuropathy.

  1999cites this paper
• Calcitonin gene-related peptide 8-37 inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.

  1999cites this paper