LAMP, a new imaging assay of gap junctional communication unveils that Ca2+ influx inhibits cell coupling

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Nature Methods

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1038/nmeth730PMID 15782161
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nature Methods

  2007cited by this paper
• Permeance of novikoff hepatoma gap junctions: Quantitative video analysis of dye transfer

  2005cited by this paper
• New caged coumarin fluorophores with extraordinary uncaging cross sections suitable for biological imaging applications.

  2004cited by this paper
• Electrical coupling and neuronal synchronization in the Mammalian brain.

  2004cited by this paper
• Beyond the gap: functions of unpaired connexon channels

  2003cited by this paper
• Cardiac Gap Junction Channels Show Quantitative Differences in Selectivity

  2002cited by this paper
• Conformational changes in surface structures of isolated connexin 26 gap junctions

  2002cited by this paper
• Gap junctions, homeostasis, and injury

  2002cited by this paper
• Emerging issues of connexin channels: biophysics fills the gap

  2001cited by this paper
• Calmodulin Directly Gates Gap Junction Channels*

  2000cited by this paper
• Gap junctions : molecular basis of cell communication in health and disease

  2000cited by this paper
• Structure/activity relationships

  1998cited by this paper
• High micromolar Ca2+ beneath the plasma membrane in stimulated neutrophils.

  1998cited by this paper
• Domains of high Ca2+ beneath the plasma membrane of living A7r5 cells

  1997cited by this paper
• Connexins, connexons, and intercellular communication.

  1996cited by this paper
• Modification of gap junction conductance by divalent cations and protons in neonatal rat heart cells.

  1995cited by this paper
• Inositol trisphosphate and calcium signalling

  1993cited by this paper
• Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells.

  1993cited by this paper
• Hemi‐gap‐junction channels in solitary horizontal cells of the catfish retina.

  1992cited by this paper
• Limitations of the dual voltage clamp method in assaying conductance and kinetics of gap junction channels.

  1992cited by this paper
• Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells.

  1990cited by this paper
• Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores.

  1989cited by this paper
• Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane.

  1989cited by this paper
• Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships.

  1988cited by this paper
• Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea‐pig.

  1987cited by this paper
• A fluorescence photobleaching assay of gap junction-mediated communication between human cells.

  1986cited by this paper
• A new generation of Ca2+ indicators with greatly improved fluorescence properties.

  1985cited by this paper
• Two configurations of a channel-forming membrane protein

  1984cited by this paper
• Nuclear envelope permeability measured by fluorescence microphotolysis of single liver cell nuclei.

  1983cited by this paper
• Gap junctional conductance: comparison of sensitivities to H and Ca ions.

  1982cited by this paper
• Intracellular pH in early Xenopus embryos: its effect on current flow between blastomeres.

  1980cited by this paper
• On the Effects of Divalent Cations Ethylene Glycol-bis-(/3-Aminoethyl N,N,N',N'-Tetraacetate on Action Potential Duration in Frog Heart and Ether)

  1978cited by this paper
• Junctional membrane permeability

  1971cited by this paper
• Junctional membrane permeability

  1971cited by this paper
• A DNA-Binding Protein Induced by Bacteriophage T7

  year unknowncited by this paper

• History of Gap Junction Architecture and Potential Role of Calmodulin in Channel Arrays

  2025cites this paper
• Calcium Role in Gap Junction Channel Gating: Direct Electrostatic or Calmodulin-Mediated?

  2024cites this paper
• DNA nanostructures for exploring cell-cell communication.

  2024cites this paper
• Gap Junction Channel Regulation: A Tale of Two Gates—Voltage Sensitivity of the Chemical Gate and Chemical Sensitivity of the Fast Voltage Gate

  2024cites this paper
• A Blue Light and Two-Photon Activatable Rhodamine Fluorophore.

  2023cites this paper
• A new player in circadian networks: Role of electrical synapses in regulating functions of the circadian clock

  2022influential citation
• Calmodulin-Connexin Partnership in Gap Junction Channel Regulation-Calmodulin-Cork Gating Model

  2021cites this paper
• OptoGap is an optogenetics-enabled assay for quantification of cell–cell coupling in multicellular cardiac tissue

  2021cites this paper
• Programming cell communications with pH-responsive DNA nanodevices.

  2021cites this paper
• Connexins: Key Players in the Control of Vascular Plasticity and Function.

  2020cites this paper
• Calmodulin-Mediated Regulation of Gap Junction Channels

  2020cites this paper
• Calmodulin-Cork Model of Gap Junction Channel Gating—One Molecule, Two Mechanisms

  2020cites this paper
• Simultaneous eco-toxicity assessment technique using an online monitoring system: effects of different environmental factors on swimming behavior of zebrafish (Danio rerio).

  2020cites this paper
• Programming Cell-Cell Communications with engineered cell origami clusters.

  2020cites this paper
• References

  2019cites this paper
• Gap-Junction-Dependent Labeling of Nascent Proteins in Multicellular Networks.

  2019cites this paper
• PARIS, an optogenetic method for functionally mapping gap junctions

  2018influential citation
• Gap Junctions in the Nervous System: Probing Functional Connections Using New Imaging Approaches

  2018cites this paper
• Impedance-Based Analysis of the Cellular Response to Microparticles: Theory, Assay Development and Model Study

  2017cites this paper
• A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopy.

  2017cites this paper
• Photoactivatable aggregation-induced emission of triphenylmethanol.

  2017cites this paper
• Gap junctional signaling in pattern regulation: Physiological network connectivity instructs growth and form

  2017cites this paper
• Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications

  2017cites this paper
• Behavior persistence in defining threshold switch in stepwise response of aquatic organisms exposed to toxic chemicals.

  2016cites this paper
• Scrape Loading/Dye Transfer Assay.

  2016cites this paper
• Calcium Wave Propagation Triggered by Local Mechanical Stimulation as a Method for Studying Gap Junctions and Hemichannels.

  2016cites this paper
• Tracking Dynamic Gap Junctional Coupling in Live Cells by Local Photoactivation and Fluorescence Imaging.

  2016cites this paper
• Obtaining More Accurate Signals: Spatiotemporal Imaging of Cancer Sites Enabled by a Photoactivatable Aptamer-Based Strategy.

  2016cites this paper
• Investigating intercellular calcium waves by microfluidic gated pinched-flow

  2016cites this paper
• Models and methods for in vitro testing of hepatic gap junctional communication.

  2015cites this paper
• Fluorescent Photochromic Diarylethene That Turns on with Visible Light.

  2015cites this paper
• Cell-Autonomous Ca(2+) Flashes Elicit Pulsed Contractions of an Apical Actin Network to Drive Apical Constriction during Neural Tube Closure.

  2015cites this paper
• Building Biomedical Materials using Photochemical Bond Cleavage

  2015cites this paper
• Étude de l'implication de la Connexine 43 dans le processus d'invasion des glioblastomes humains

  2015cites this paper
• Genetic targeting of a small fluorescent zinc indicator to cell surface for monitoring zinc secretion.

  2015cites this paper
• Block-Cell-Printing for live single-cell printing

  2014cites this paper
• Controlling cell–cell interactions using surface acoustic waves

  2014cites this paper
• Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans

  2014influential citation
• Photoactivatable fluorescein derivatives caged with a (3-hydroxy-2-naphthalenyl)methyl group.

  2014cites this paper
• Photoactivatable Fluorophores

  2014cites this paper
• Photoactivatable synthetic fluorophores.

  2013cites this paper
• Connexin targeting peptides as inhibitors of voltage- and intracellular Ca2+-triggered Cx43 hemichannel opening.

  2013cites this paper
• A microdevice for studying intercellular electromechanical transduction in adult cardiac myocytes.

  2013cites this paper
• Microengineered Platforms For Assessing Cell-Cell Communication and Single-Cell Influences on Adult Neural Stem Cell Fate

  2012cites this paper
• Image‐Predicated Sorting of Adherent Cells Using Photopatterned Hydrogels

  2012cites this paper
• Regulation of intercellular calcium signaling through calcium interactions with connexin-based channels.

  2012cites this paper
• Intercellular Ca(2+) waves: mechanisms and function.

  2012cites this paper
• Coordination of calcium signals by pituitary endocrine cells in situ.

  2012cites this paper
• Photoactivatable fluorophores and techniques for biological imaging applications

  2012cites this paper
• Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans

  2012influential citation
• Role of Integrative Signaling Through Gap Junctions in Toxicology

  2011cites this paper
• Floating Skeleton Concept

  2011cites this paper
• Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis : focus on the soluble factor angiopoietin-1 and direct contact via lamimim-1/α6β1 integrin and connexin 43 as new targets for brain repair

  2011cites this paper
• Assay for molecular transport across gap junction channels in one-dimensional cell arrays.

  2011cites this paper
• Chloral hydrate decreases gap junction communication in rat liver epithelial cells

  2011cites this paper
• Visualising the Inter- and Extra-cellular Diffusion Pathways In Rodent Lenses

  2011cites this paper
• ocyte triplet pairing for electrophysiological investigation of gap junctional oupling

  2010cites this paper
• Photoactive molecules for applications in molecular imaging and cell biology.

  2010cites this paper
• Inexpensive technologies enabling widespread utilization of image-predicated cell sorting

  2010influential citation
• Non-invasive microfluidic gap junction assay.

  2010cites this paper
• Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts.

  2010cites this paper
• Oocyte triplet pairing for electrophysiological investigation of gap junctional coupling.

  2010cites this paper
• Coumarin-caged rosamine probes based on a unique intramolecular carbon-carbon spirocyclization.

  2010cites this paper
• Quantitation of green fluorescent protein using a gel-based imaging method.

  2009cites this paper
• Calcium spikes in a leech nonspiking neuron

  2009cites this paper
• Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity

  2009cites this paper
• Assaying dynamic cell–cell junctional communication using noninvasive and quantitative fluorescence imaging techniques: LAMP and infrared-LAMP

  2009cites this paper
• Function of connexins in the renal circulation.

  2008cites this paper
• Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMP

  2008cites this paper
• In situ bipolar electroporation for localized cell loading with reporter dyes and investigating gap junctional coupling.

  2008cites this paper
• Calcium cycling and signaling in cardiac myocytes.

  2008cites this paper
• Regulation of Connexin40 Gap Junctions

  2008influential citation
• Advantages and limitations of commonly used methods to assay the molecular permeability of gap junctional intercellular communication.

  2008influential citation
• Hindered diffusion through an aqueous pore describes invariant dye selectivity of Cx43 junctions.

  2008cites this paper
• Nature Methods

  2007cites this paper
• Unitary permeability of gap junction channels to second messengers measured by FRET microscopy

  2007cites this paper
• Gap junctional communication in morphogenesis.

  2007cites this paper
• Propagation of the cardiac impulse in the diabetic rat heart: reduced conduction reserve

  2007cites this paper
• Hormonal, pH, and Calcium Regulation of Connexin 43–Mediated Dye Transfer in Osteocytes in Chick Calvaria

  2007cites this paper
• Photoactivatable and water soluble FRET dyes with high uncaging cross section.

  2007cites this paper
• Intracellular calcium regulation of connexin43.

  2007influential citation
• The gap junction cellular internet: connexin hemichannels enter the signalling limelight.

  2006cites this paper
• Intracellular calcium changes trigger connexin 32 hemichannel opening

  2006cites this paper
• Effect of Adrenalin, Adrenochrome, and Adrenolutin on Connexin Proteins in the Cardiovasculature

  2006influential citation
• Local Ca2+ Rise Near Store Operated Ca2+ Channels Inhibits Cell Coupling During Capacitative Ca2+ Influx

  2006influential citation
• Chemistry comes to the cell: ASCB 2005

  2006cites this paper
• Flow cytometry analysis of gap junction‐mediated cell–cell communication: Advantages and pitfalls

  2006cites this paper
• Shapes of astrocyte networks in the juvenile brain.

  2006cites this paper
• Infrared-LAMP: two-photon uncaging and imaging of gap junctional communication in three dimensions

  2006cites this paper
• Optical molecular imaging for systems biology: from molecule to organism

  2006cites this paper
• Functional connexin “hemichannels”: A critical appraisal

  2006cites this paper
• A Three‐Dimensional Model of Intercellular Calcium Signaling in Epithelial Cells

  2005cites this paper
• Quantification of gap junction selectivity.

  2005cites this paper
• Two‐Photon Excitation Microscopy for the Study of Living Cells and Tissues

  2003influential citation
• Intercellular Calcium Signaling in a Gap Junction- Coupled Cell Network Establishes Asymmetric Neuronal Fates in C. Elegans Repository Citation Intercellular Calcium Signaling in a Gap Junction-coupled Cell Network Establishes Asymmetric Neuronal Fates in C. Elegans

  year unknowncites this paper