Research status and prospect of stem cells in the treatment of diabetes mellitus

Beta cell mass and function are decreased to varying degrees in diabetes. Islet cell replacement or regenerative therapy may offer great therapeutic promise to people with diabetes. In addition to primary pancreatic β cells, recent studies on regeneration of functional insulin producing cells (IPCs) revealed that several alternative cell sources, including embryonic stem cells, induced pluripotent stem cells and adult stem cells, can generate IPCs by differentiation, reprogramming, and trans-differentiation. In this review, we discuss stem cells as a potential alternative cell source for the treatment of diabetes.

• Publication year

  2013

• Venue

  Science China Life Sciences

• Publication date

  2013-04-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s11427-013-4469-1PMID 23564185
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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