The role of free radicals in canine counterpart of senile dementia of the Alzheimer type.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Experimental Gerontology

• Publication date

  2003-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0531-5565(03)00071-8PMID 12814808
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Oxygen effect in the radiolysis of proteins. IV. Myoglobin.

  2009cited by this paper
• Short-term consumption of a high-sucrose diet has a pro-oxidant effect in rats

  2002cited by this paper
• Short-term consumption of a high-sucrose diet has a pro-oxidant effect in rats.

  2002cited by this paper
• Feeding Fried Oil Changes Antioxidant and Fatty Acid Pattern of Rat and Affects Rat Liver Mitochondrial Respiratory Chain Components

  2002cited by this paper
• Oxidative damage increases with age in a canine model of human brain aging

  2002cited by this paper
• The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses.

  2001cited by this paper
• Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.

  2001cited by this paper
• Say NO to Alzheimer's disease: the putative links between nitric oxide and dementia of the Alzheimer's type.

  2001cited by this paper
• Increased protein glycation in cerebrospinal fluid of Alzheimer's disease.

  2001cited by this paper
• Letter to Neuroscience FIBRILLAR L-AMYLOID EVOKES OXIDATIVE DAMAGE IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE

  2001cited by this paper
• Antioxidant vitamin levels and glutathione peroxidase activity during ischemia/reperfusion in myocardial infarction.

  2001cited by this paper
• Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques

  2001cited by this paper
• Fibrillar β-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer’s disease

  2001cited by this paper
• Chemistry and biochemistry of oxidative stress in neurodegenerative disease.

  2001cited by this paper
• Highly sensitive diagnosis of amyloid and various amyloid syndromes using Congo red fluorescence

  2000cited by this paper
• Oxidative stress in Alzheimer's disease.

  2000cited by this paper
• Vascular and parenchymal Abeta deposition in the aging dog: correlation with behavior.

  2000cited by this paper
• Oxidative stress and Alzheimer disease.

  2000cited by this paper
• Regulation of APP cleavage by alpha-, beta- and gamma-secretases.

  2000cited by this paper
• Oxidative Alterations in Alzheimer's Disease

  1999cited by this paper
• Hypoxia induces free radical damage to rat erythrocytes and spleen: analysis of the fluorescent end-products of lipid peroxidation.

  1999cited by this paper
• Investigations on oxidative stress and therapeutical implications in dementia

  1999cited by this paper
• Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease.

  1999cited by this paper
• Reactive oxygen-mediated protein oxidation in aging and disease.

  1998cited by this paper
• The role of metal-catalyzed oxidation in the formation of advanced glycation end products: an in vitro study on collagen.

  1998cited by this paper
• The generation of superoxide anions in glycation reactions with sugars, osones, and 3-deoxyosones.

  1998cited by this paper
• Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase.

  1997cited by this paper
• Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease.

  1997cited by this paper
• Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

  1997cited by this paper
• Biochemistry and pathology of radical-mediated protein oxidation.

  1997cited by this paper
• Reactive oxygen-mediated protein oxidation in aging and disease.

  1997cited by this paper
• Oxidative damage to protein and alterations to antioxidant levels in human cutaneous thermal injury.

  1997cited by this paper
• Apoptosis in the aged dog brain

  1996cited by this paper
• Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.

  1996cited by this paper
• Biochemical basis of lipofuscin, ceroid, and age pigment-like fluorophores.

  1996cited by this paper
• Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine.

  1996cited by this paper
• Formation of lipofuscin in cultured retinal pigment epithelial cells exposed to pre‐oxidized photoreceptor outer segments

  1996cited by this paper
• Genotypic selection of mitochondrial and oncogenic mutations in human tissue suggests mechanisms of age-related pathophysiology.

  1995cited by this paper
• Measurement of serum lipid peroxidation during exercise using three different methods: diene conjugation, thiobarbituric acid reactive material and fluorescent chromolipids.

  1995cited by this paper
• Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy.

  1995cited by this paper
• Lipid peroxidation and ceroid accumulation in macrophages cultured with oxidized low density lipoprotein.

  1995cited by this paper
• Cortical Cytochrome Oxidase Activity Is Reduced in Alzheimer's Disease

  1994cited by this paper
• Oxidative damage and mitochondrial decay in aging.

  1994cited by this paper
• Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease.

  1993cited by this paper
• β-Amyloid accumulation in aged canine brain: A model of early plaque formation in Alzheimer's disease

  1993cited by this paper
• Oxygen effect in the radiolysis of proteins. III. Haemoglobin.

  1993cited by this paper
• Oxidants, antioxidants, and the degenerative diseases of aging.

  1993cited by this paper
• Morphometric Analysis of Microglia in Alzheimer's Disease

  1993cited by this paper
• Oxidative damage to collagen.

  1992cited by this paper
• Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing.

  1989cited by this paper
• Time course of lipolytic activity and lipid peroxidation after whole-body gamma irradiation of rats.

  1989cited by this paper
• Liver mitochondrial respiratory functions decline with age.

  1989cited by this paper
• Changes of lipofuscin-like pigments in erythrocytes and spleen after whole-body gamma irradiation of rats.

  1989cited by this paper
• Oxygen effect in the radiolysis of proteins. Part 2. Bovine serum albumin.

  1984cited by this paper
• Cytotoxic aldehydes originating from the peroxidation of liver microsomal lipids. Identification of 4,5-dihydroxydecenal.

  1984cited by this paper
• Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes.

  1982cited by this paper
• Is cell aging caused by respiration-dependent injury to the mitochondrial genome?

  1982cited by this paper
• Time-course of changes in lipofuscin-like pigments in rat liver homogenate and mitochondria after whole body gamma irradiation

  1981cited by this paper
• The chromosomal location of phosphatase isozymes of the wheat endosperm

  1981cited by this paper
• Oxygen effect in the radiolysis of proteins. I. Lactate dehydrogenase.

  1980cited by this paper
• Spectrofluorescent detection of in vivo red cell lipid peroxidation in patients treated with diaminodiphenylsulfone.

  1976cited by this paper
• The determination of trace elements in human fingernails by atomic absorption spectroscopy.

  1971cited by this paper
• Synthesis and characterization of the fluorescent products derived from malonaldehyde and amino acids.

  1969cited by this paper
• The anti-oxidant effect of serotonin.

  1957cited by this paper
• Aging: a theory based on free radical and radiation chemistry.

  1956cited by this paper

• Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

  2024cites this paper
• Feline Cognition and the Role of Nutrition: An Evolutionary Perspective and Historical Review

  2024cites this paper
• Lipophilic fluorescent products as a potential biomarker of oxidative stress: A link between central (brain) and peripheral (blood)

  2024cites this paper
• Integrative Nutritional Therapy in Canine Cognitive Dysfunction

  2023cites this paper
• Research Models to Study Ferroptosis’s Impact in Neurodegenerative Diseases

  2023cites this paper
• Assessment of lipophilic fluorescence products in β-amyloid-induced cognitive decline: A parallel track in hippocampus, CSF, plasma and erythrocytes.

  2021cites this paper
• Isoprostanes in Veterinary Medicine: Beyond a Biomarker

  2021cites this paper
• Characterization of lipid peroxidation products formed during ageing of tobacco leaves and effect of manipulated ageing

  2020cites this paper
• Simultaneous exposure to noise and carbon monoxide increases the risk of Alzheimer's disease: a literature review

  2020cites this paper
• Nutraceuticals for Cognitive Dysfunction

  2019cites this paper
• Molecular Chaperones and Protein Quality Control System in the Canine Model of Brain Aging and Neurodegenerative Diseases

  2019cites this paper
• Genetic Pathways of Aging and Their Relevance in the Dog as a Natural Model of Human Aging

  2019cites this paper
• CANINE COGNITIVE DISFUNCTION SYNDROME

  2018cites this paper
• Special Considerations for Diagnosing Behavior Problems in Older Pets.

  2018cites this paper
• The Aged Dog as a Natural Model of Alzheimer’s Disease Progression

  2017cites this paper
• The oil-rich alga Schizochytrium sp. as a dietary source of docosahexaenoic acid improves shape discrimination learning associated with visual processing in a canine model of senescence.

  2017cites this paper
• Pyridoindole SMe1EC2 as cognition enhancer in ageing-related cognitive decline

  2017cites this paper
• Brain Aging in the Dog

  2017cites this paper
• NOVEL TARGETS FOR MITOCHONDRIAL DYSFUNCTION FOLLOWING TRAUMATIC BRAIN INJURY

  2016cites this paper
• Immunohistochemical distribution of the cannabinoid receptor 1 and fatty acid amide hydrolase in the dog claustrum.

  2016cites this paper
• Analysis of lipophilic fluorescent products in blood of Alzheimer's disease patients

  2016cites this paper
• Dogs with Cognitive Dysfunction as a Spontaneous Model for Early Alzheimer’s Disease: A Translational Study of Neuropathological and Inflammatory Markers

  2016cites this paper
• Targeting Mitochondria for Healthy Brain Aging

  2015cites this paper
• Parvalbumin expression in the claustrum of the adult dog. An immunohistochemical and topographical study with comparative notes on the structure of the nucleus.

  2015cites this paper
• Why is the dog an ideal model for aging research?

  2015cites this paper
• Oxidative Stress and Protein Quality Control Systems in the Aged Canine Brain as a Model for Human Neurodegenerative Disorders

  2015cites this paper
• Aging in the canine and feline brain.

  2014cites this paper
• IMMUNOTHERAPY IN COMBINATION WITH BEHAVIORAL ENRICHMENT IN A CANINE MODEL OF AGING

  2014cites this paper
• Prevention approaches in a preclinical canine model of Alzheimer’s disease: benefits and challenges

  2014cites this paper
• Cognitive dysfunction syndrome: updated behavioral and clinical evaluations as a tool to evaluate the well-being of aging dogs Síndrome de disfunción cognitiva: actualización del conocimiento como herramienta para el bienestar animal en perros seniles

  2014cites this paper
• Lipophilic fluorescent products of free radicals.

  2013cites this paper
• An observational study with long-term follow-up of canine cognitive dysfunction: clinical characteristics, survival, and risk factors.

  2013cites this paper
• Rapid improvement of canine cognitive dysfunction with immunotherapy designed for Alzheimer's disease.

  2013cites this paper
• A canine model of human aging and Alzheimer's disease.

  2013cites this paper
• White matter myelin loss in the brains of aged dogs.

  2012cites this paper
• Blood markers of oxidative stress in Alzheimer's disease

  2012cites this paper
• Dogs with cognitive dysfunction syndrome: a natural model of Alzheimer's disease.

  2012cites this paper
• Antioxidants in the canine model of human aging.

  2012cites this paper
• End products of lipid peroxidation in erythrocyte membranes in Alzheimer's disease

  2012cites this paper
• EFEITOS DA CURCUMINA E DO RESVERATROL EM RATOS COM PARKINSONISMO EXPERIMENTAL INDUZIDO POR 6-HIDROXIDOPAMINA: UM ESTUDO COMPORTAMENTAL E NEUROQUÍMICO

  2012cites this paper
• Effects of isoflurane on learning and memory functions of wild‐type and glutamate transporter type 3 knockout mice

  2012cites this paper
• Biogerontology in the Czech Republic

  2011cites this paper
• Neurobiology of the aging dog

  2011cites this paper
• Plasma β-amyloid peptides in canine aging and cognitive dysfunction as a model of Alzheimer's disease.

  2011cites this paper
• Impact of Aging on Brain Structure and Function in Rodents and Canines

  2011cites this paper
• HPLC Separation of Fluorescent Products of Lipid Peroxidation in Erythrocytes and Mitochondria

  2011cites this paper
• Oxidative Stress, Cognitive Dysfunction, and Brain Aging

  2011cites this paper
• The lipid peroxidation products as possible markers of Alzheimer's disease in blood.

  2011cites this paper
• Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging

  2010cites this paper
• Synergistic Effects of Long-Term Antioxidant Diet and Behavioral Enrichment on β-Amyloid Load and Non-Amyloidogenic Processing in Aged Canines

  2010cites this paper
• Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.

  2009cites this paper
• Micronutrient Antioxidants, Cognition, and Neuropathology: A Longitudinal Study in the Canine Model of Human Aging

  2009cites this paper
• Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging.

  2009cites this paper
• CHAPTER 2 – Canine Behavior of Sensory and Neural Origin

  2009cites this paper
• β‐amyloid cortical deposits are accompanied by the loss of serotonergic neurons in the dog

  2009cites this paper
• Oxidative Damage and Cognitive Dysfunction: Antioxidant Treatments to Promote Healthy Brain Aging

  2009cites this paper
• Strategies for improving cognition with aging: insights from a longitudinal study of antioxidant and behavioral enrichment in canines

  2009cites this paper
• Advanced Protocols in Oxidative Stress I

  2008cites this paper
• Oxidative stress, aging, and central nervous system disease in the canine model of human brain aging.

  2008cites this paper
• Aging, Aluminium and Basal Forebrain Lesions Modify Substrate Kinetics of Erythrocyte Membrane Na,K-ATPase in the Rat

  2008cites this paper
• An update on using vitamin E in Alzheimer's disease

  2008cites this paper
• An experimental study of hemolysis induced by onion (Allium cepa) poisoning in dogs.

  2008cites this paper
• Preparation of a multi-antioxidant formulation.

  2008cites this paper
• Region specific neuron loss in the aged canine hippocampus is reduced by enrichment.

  2008cites this paper
• Redox proteomics studies of in vivo amyloid beta‐peptide animal models of Alzheimer's disease: Insight into the role of oxidative stress

  2008cites this paper
• Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine.

  2008cites this paper
• Phosphatidylserine (PS) as a potential nutraceutical for canine brain aging: A review

  2008cites this paper
• Oxidative Stress, Aging and CNS disease in the Canine Model of Human Brain Aging

  2008cites this paper
• The Canine (Dog) Model of Human Aging and Disease: Dietary, Environmental and Immunotherapy Approaches

  2008cites this paper
• Hypercapnia protects erythrocytes against free radical damage induced by hypoxia in exposed rats

  2008cites this paper
• Combining an Antioxidant‐Fortified Diet with Behavioral Enrichment Leads to Cognitive Improvement and Reduced Brain Pathology in Aging Canines

  2007cites this paper
• Canine cognitive dysfunction syndrome: Prevalence, clinical signs and treatment with a neuroprotective nutraceutical

  2007cites this paper
• The effects of reactive oxygen and nitrogen species during yeast replicative ageing

  2006cites this paper
• Silybin reduces lipid peroxidation of rat hepatocyte membrane caused by cyclosporin A

  2006cites this paper
• Therapeutic options for cognitive decline in senior pets.

  2006cites this paper
• Cognitive disturbances in old dogs suffering from the canine counterpart of Alzheimer's disease.

  2006cites this paper
• Nutritional Antioxidant Enrichment and Improved Cognitive Function in Canines

  2005cites this paper
• Nutrition for aging cats and dogs and the importance of body condition.

  2005cites this paper
• Erythrocyte membranes inhibit respiratory burst and protein nitration during phagocytosis by macrophages.

  2005cites this paper
• Therapeutic agents for the treatment of cognitive dysfunction syndrome in senior dogs.

  2005cites this paper
• VALUTAZIONE DELL'EFFETTO E DELLA TOLLERABILITÀ DI UN NUTRACEUTICO NEUROPROTETTIVO CONTENENTE FOSFATIDILSERINA E GINKGO BILOBA SUI SEGNI CLINICI DI INVECCHIAMENTO CEREBRALE NEL CANE: STUDIO PILOTA MULTICENTRICO ✥

  2005cites this paper
• Protein folding pathology in domestic animals.

  2004cites this paper
• Ageing and oxidative stress: A role for dolichol in the antioxidant machinery of cell membranes?

  2004cites this paper
• γ‐aminobutyric acidergic interneuron vulnerability to aging in canine prefrontal cortex

  2004cites this paper
• Erythrocyte aging in neurodegenerative disorders.

  2004cites this paper
• Vitamin E in Neurodegenerative Disorders: Alzheimer's Disease

  2004cites this paper
• Effect of selenium pre-treatment on evoked cortical afterdischarges in young rats.

  2004cites this paper
• Histochemical accumulation of oxidative damage products is associated with Alzheimer-like pathology in the canine

  2004cites this paper
• Protein folding pathology in domestic animals

  2004cites this paper
• Significance of Romhanyi's scientific work to study amyloid and amyloid-related proteins in animals.

  2003cites this paper
• Canine counterpart of senile dementia of the Alzheimer type: amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages

  2003cites this paper
• TRADITION AND MODERNITY IN VETERINARY MEDICINE, 2021, vol. 6, No 2(11): 121–129 OVERVIEW OF COGNITIVE DYSFUNCTION SYNDROME IN AGEING DOGS

  year unknowncites this paper