Compatibility Factors Influencing the Acceptance of Rat Bone Marrow Graft by the Irradiated Mouse **

Studies on marrow from humans, guinea pigs, rats, rabbits, and hamsters showed that rat bone marrow is the only heterologous marrow that is acceptable to the irradiated mouse. Other rodent erythrocytes are basically incompatible in the mouse and are rapidly destroyed even by the irradiated mouse recipient. The implications of the findings in relation to the acceptance of heterologous bone marrow grafts are discussed. One suggestion is the marked antigenic similarity of the mouse and rat erythrocyte. (P.C.H.)

• Publication year

  1958

• Venue

  The Yale Journal of Biology and Medicine

• Publication date

  1958-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 13625738PMCID 2603958
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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